Search Results - "Kulkarni, Rohan"

Early Growth Response Factor 1 in Aging Hematopoietic Stem Cells and Leukemia by Kulkarni, Rohan

“…Aging is associated with various hematological disorders and a higher risk of myeloproliferative disorders. An aged hematopoietic system can be characterized…”
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Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing by Valentine, Charles C., Young, Robert R., Fielden, Mark R., Kulkarni, Rohan, Williams, Lindsey N., Li, Tan, Minocherhomji, Sheroy, Salk, Jesse J.

“…The ability to accurately measure mutations is critical for basic research and identifying potential drug and chemical carcinogens. Current methods for in vivo…”
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Physiological Cues Involved in the Regulation of Adhesion Mechanisms in Hematopoietic Stem Cell Fate Decision by Kulkarni, Rohan, Kale, Vaijayanti

“…Hematopoietic stem cells (HSC) could have several fates in the body; viz. self-renewal, differentiation, migration, quiescence, and apoptosis. These fate…”
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The efficient synthesis and purification of 2′3’- cGAMP from Escherichia coli by Kulkarni, Rohan, Maranholkar, Vijay, Nguyen, Nam, Cirino, Patrick C., Willson, Richard C., Varadarajan, Navin

“…Agonists of the stimulator of interferon genes (STING) pathway are being explored as potential immunotherapeutics for the treatment of cancer and as vaccine…”
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Examining Historical Data to Inform Future Preparedness: Systematic Review of the Effects of Prone Positioning on Oxygen Levels in Nonintubated COVID-19 Patients by Kulkarni, Rohan, Padwal, Siddharth, More, Prashant, Patil, Salil

“…Abstract Over time, there has been a significant increase in the utilization of prone positioning (PP) as a strategy to improve oxygen levels in patients…”
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Induction and Detection of Autophagy in Aged Hematopoietic Stem Cells by Exposing Them to Microvesicles Secreted by HSC-Supportive Mesenchymal Stromal Cells by Kulkarni, Rohan S, Bajaj, Manmohan S, Kale, Vaijayanti P

“…Autophagy is an important cellular process for maintenance of quality and functionality of cells. This happens through repair and renewal of cellular…”
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COVID-associated acute limb ischemia during the Delta surge and the effect of vaccines by Xie, Bowen, Semaan, Dana B., Binko, Mary A., Agrawal, Nishant, Kulkarni, Rohan N., Andraska, Elizabeth A., Sachdev, Ulka, Chaer, Rabih A., Eslami, Mohammad H., Makaroun, Michel S., Sridharan, Natalie

“…Hypercoagulability is common in severe acute respiratory syndrome coronavirus 2 and has been associated with arterial thrombosis leading to acute limb ischemia…”
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Multi-antigen intranasal vaccine protects against challenge with sarbecoviruses and prevents transmission in hamsters by Leekha, Ankita, Saeedi, Arash, Sefat, K M Samiur Rahman, Kumar, Monish, Martinez-Paniagua, Melisa, Damian, Adrian, Kulkarni, Rohan, Reichel, Kate, Rezvan, Ali, Masoumi, Shalaleh, Liu, Xinli, Cooper, Laurence J. N., Sebastian, Manu, Sands, Courtney M., Das, Vallabh E., Patel, Nimesh B., Hurst, Brett, Varadarajan, Navin

“…Immunization programs against SARS-CoV-2 with commercial intramuscular vaccines prevent disease but are less efficient in preventing infections. Mucosal…”
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An intranasal nanoparticle STING agonist protects against respiratory viruses in animal models by Leekha, Ankita, Saeedi, Arash, Kumar, Monish, Sefat, K. M. Samiur Rahman, Martinez-Paniagua, Melisa, Meng, Hui, Fathi, Mohsen, Kulkarni, Rohan, Reichel, Kate, Biswas, Sujit, Tsitoura, Daphne, Liu, Xinli, Cooper, Laurence J. N., Sands, Courtney M., Das, Vallabh E., Sebastian, Manu, Hurst, Brett L., Varadarajan, Navin

“…Respiratory viral infections cause morbidity and mortality worldwide. Despite the success of vaccines, vaccination efficacy is weakened by the rapid emergence…”
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Three cases of acute venous thromboembolism in females after vaccination for coronavirus disease 2019 by Andraska, Elizabeth A., Kulkarni, Rohan, Chaudhary, Mirnal, Sachdev, Ulka

“…Since December 2020, four vaccines for SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) have been developed, and three have been approved for…”
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Methylation-dependent antioxidant-redox imbalance regulates hypertensive kidney injury in aging by Pushpakumar, Sathnur, Ren, Lu, Juin, Subir Kumar, Majumder, Suravi, Kulkarni, Rohan, Sen, Utpal

“…The prevalence of hypertension increases with age, and oxidative stress is a major contributing factor to the pathogenesis of hypertension-induced kidney…”
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Journey of Natural Killer Cells and their Role in Liver Diseases by Buch, Archana, Kulkarni, Rohan S, Kulkarni, Saagar S, Bhandari, Parul

“…Natural Killer (NK) cells are the key lymphocyte subset of the natural immune system that arbitrates antiviral and anticancer responses. In the human body NK…”
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Brain Computer Interface for Emotion Recognition Based on EEG Signal by Shilaskar, Swati, Bhatlawande, Shripad, Kulkarni, Rohan, Lonkar, Tanmay

“…This paper presents an emotion recognition system based on electroencephalography (EEG) signals. This system helps medical practitioners to analyse the mental…”
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Decoding the mechanisms of chimeric antigen receptor (CAR) T cell-mediated killing of tumors: insights from granzyme and Fas inhibition by Montalvo, Melisa J., Bandey, Irfan N., Rezvan, Ali, Wu, Kwan-Ling, Saeedi, Arash, Kulkarni, Rohan, Li, Yongshuai, An, Xingyue, Sefat, K M Samiur Rahman, Varadarajan, Navin

“…Chimeric antigen receptor (CAR) T cell show promise in cancer treatments, but their mechanism of action is not well understood. Decoding the mechanisms used by…”
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Structural Remodeling of the Extracellular Matrix in Arteriogenesis: A Review by Kulkarni, Rohan, Andraska, Elizabeth, McEnaney, Ryan

“…Lower extremity arterial occlusive disease (AOD) results in significant morbidity and mortality for the population, with up to 10% of patients ultimately…”
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Targeting BRD4 in acute myeloid leukemia with partial tandem duplication of the MLL gene by Bill, Marius, Goda, Chinmayee, Pepe, Felice, Ozer, Hatice Gulcin, McNeil, Betina, Zhang, Xiaoli, Karunasiri, Malith, Kulkarni, Rohan, Kalyan, Sonu, Papaioannou, Dimitrios, Ferenchak, Gregory, Garzon, Ramiro, Bradner, James E, Marcucci, Guido, Caligiuri, Michael A, Dorrance, Adrienne M

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The Aim2 Inflammasome Deters Myogenic Potential of Muscle Satellite Cells Affected by Peripheral Artery Disease and Is a Therapeutic Target to Attenuate Myopathy by Xie, Bowen, Assaf, Edwyn, Ferrari, Ricardo, Kulkarni, Rohan, McEnaney, Ryan, Sachdev, Ulka

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Neuropilin-1 Is an Important Niche Component and Exerts Context-Dependent Effects on Hematopoietic Stem Cells by Ghode, Suprita S, Bajaj, Manmohan S, Kulkarni, Rohan S, Limaye, Lalita S, Shouche, Yogesh S, Kale, Vaijayanti P

“…Marrow adipocytes pose a significant problem in post-transplant regeneration of hematopoiesis owing to their negative effects on regeneration of hematopoiesis…”
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Development and performance analysis of solar photovoltaic–thermal (PVT) systems by Kulkarni, Rohan S, Talange, Dhananjay B, Dharme, Anjali A, Mate, Nitant V

“…The photovoltaic–thermal (PVT) systems have been established for providing both electricity and heat using the existing photovoltaic (PV) system set-up. The…”
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Simultaneous Upregulation of Elastolytic and Elastogenic Factors Are Necessary for Regulated Collateral Diameter Expansion by Andraska, Elizabeth, Skirtich, Nolan, McCreary, Dylan, Kulkarni, Rohan, Tzeng, Edith, McEnaney, Ryan

“…During arteriogenesis, outward remodeling of the arterial wall expands luminal diameter to produce increased conductance in developing collaterals. We have…”
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