Search Results - "Kulkarni, Manohar V"
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Synthesis and biological evaluation of novel angularly fused polycyclic coumarins
Published in Bioorganic & medicinal chemistry letters (01-08-2005)“…Novel angularly fused pentacyclic heterocycles with coumarin and benzofuran fused to the pyridine ring were synthesized and show promising anti-inflammatory…”
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One pot Click chemistry: A three component reaction for the synthesis of 2-mercaptobenzimidazole linked coumarinyl triazoles as anti-tubercular agents
Published in Bioorganic & medicinal chemistry letters (01-10-2016)“…[Display omitted] •One pot synthesis and characterization of mercapto-coumarinyl triazoles.•Formation of 1,4 isomer under Cu(I) Click…”
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3
Crystal structure of 4-(4b,8a-di-hydro-9H-pyrido[3,4-b]indol-1-yl)-7-methyl-2H-chromen-2-one
Published in Acta crystallographica. Section E, Crystallographic communications (01-01-2017)“…The title compound, C21H14N2O2, was prepared by Pictet-Spengler cyclization of tryptamine and 4-formyl coumarin. In the mol-ecule, the dihedral angle between…”
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Click chemistry approach for the regioselective synthesis of iso-indoline-1,3-dione-linked 1,4 and 1,5 coumarinyl 1,2,3-triazoles and their photophysical properties
Published in Synthetic communications (03-04-2017)“…Copper-catalyzed reaction of N-propargyl isoindoline-1,3-dione and 4-azidomethyl coumarins / 4-azidomethyl-1-aza coumarins under click chemistry conditions…”
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A click chemistry approach for the synthesis of mono and bis aryloxy linked coumarinyl triazoles as anti-tubercular agents
Published in European journal of medicinal chemistry (13-11-2015)“…A series of mono and bis-triazole coumarin hybrids 6a–u and 9a–f respectively have been synthesized using 4-(azidomethyl)-2H-chromen-2-ones 5a–i and aryl…”
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A click chemistry approach for the synthesis of cyclic ureido tethered coumarinyl and 1-aza coumarinyl 1,2,3-triazoles as inhibitors of Mycobacterium tuberculosis H37Rv and their in silico studies
Published in Bioorganic & medicinal chemistry (15-10-2019)“…[Display omitted] •Cyclic ureido based mono/bis-coumarin ‘click triazoles’ have been synthesized.•Newly synthesized triazoles inhibited Mycobacterium…”
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Crystal Structure of 6-Methyl-4-[(quinolin-8-yloxy)methyl]-2H-chromen-2-one
Published in X-ray Structure Analysis Online (2013)“…The title compound, 6-methyl-4-[(quinolin-8-yloxy)methyl]-2H-chromen-2-one, crystallizes under a monoclinic system with space group P21/c. The unit cell…”
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Synthesis and antimicrobial studies on novel sulfonamides containing 4-azidomethyl coumarin
Published in European journal of medicinal chemistry (01-03-2010)“…A series of new and novel coumarin-6-sulfonamides with a free C4-azidomethyl group have been synthesized as antimicrobials in three steps starting from…”
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Transition metal complexes of a potential anticancer quinazoline ligand
Published in Transition metal chemistry (Weinheim) (01-04-2009)“…A new heterocycle, namely 2-(furyl)-3-(furfuralimino)-1,2-dihydroquinazolin-4(3H)-one (ffdq) was formed by the condensation of 2-aminobenzoylhydrazide with…”
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Rhodium-Catalyzed Regioselective Synthesis of Isocoumarins through Benzothiadiazine-Fused Frameworks
Published in Organic letters (05-08-2016)“…An unprecedented two-step, one-pot synthesis of benzimidazothiadiazine 5,5-dioxides is presented. Reaction condition based regioselectivity has been achieved…”
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Role of Substituent Position in Coumarin Derivatives during their Interaction with TiO2 Nano Particles
Published in Journal of fluorescence (01-05-2021)“…The effect of position of benzo group in coumarin derivatives, 5,6 benzo-4-azidomethyl coumarin (5BAMC) and 7,8 benzo-4-azidomethyl coumarin (7BAMC) during…”
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12
Crystal Structure of 1-((Bis(2-hydroxyethyl)amino)methyl)-3H-benzo[f]chromen-3-one
Published in X-ray Structure Analysis Online (2012)“…The title compound, 1-((bis(2-hydroxyethyl)amino)methyl)-3H-benzo[f]chromen-3-one, crystallizes in triclinic systems, with space group P1. The unit-cell…”
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Cu (I) Catalyzed One Pot SN‐Click Reactions of Halogenated Coumarins and 1‐aza‐coumarins
Published in Journal of heterocyclic chemistry (01-02-2018)“…A one pot three component, copper catalyzed azide‐alkyne cycloaddition reaction has been employed for the synthesis of bis‐coumarinyl triazoles (A–D) using…”
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6-Chloro-4-(4-methyl-phen-oxy-meth-yl)-2H-chromen-2-one
Published in Acta crystallographica. Section E, Structure reports online (01-07-2011)“…In the title compound, C(17)H(13)ClO(3), the coumarin and phen-oxy moieties are essentially co-planar, making a dihedral angle of 1.99 (7)°. The phen-oxy…”
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Recent advances in coumarins and 1-azacoumarins as versatile biodynamic agents
Published in Current medicinal chemistry (01-10-2006)“…Coumarins, also referred as benzopyran-2-ones, and their corresponding nitrogen counterpart, 1-azacoumarins also referred to as carbostyrils, are a family of…”
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Synthesis, biological evaluation and docking studies of 4-aryloxymethyl coumarins derived from substructures and degradation products of vancomycin
Published in European journal of medicinal chemistry (01-12-2013)“…Two series of 4-aryloxymethyl coumarins derived from the reaction of 4-bromomethyl coumarins with ethyl gallate and ethyl ester of N-Benzoyl tyrosine have been…”
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Click Chemistry Approach for Bis-Chromenyl Triazole Hybrids and Their Antitubercular Activity
Published in Chemical biology & drug design (01-10-2012)“…1,4‐Disubstituted bis‐chromenyl triazole hybrids 5a–m have been synthesized in a three‐step reaction sequence from 4‐(bromomethyl)‐2H‐chromen‐2‐ones 3a–m. The…”
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18
Novel One-Pot Synthesis for 2,5-Diaryl and 5-Aryl-pyridazin-3(2H)-ones
Published in Synthetic communications (01-09-2011)“…A novel method for the synthesis of 2-phenyl-5-(o-hydroxyphenyl)-pyridazin-3(2H)-ones and 5-(o-hydroxyphenyl)-pyridazin-3(2H)-ones has been found during the…”
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19
Modified Riemschneider reaction as a new route for the synthesis of coumarinyl and 1-aza coumarinyl thioethers
Published in Journal of sulfur chemistry (02-01-2019)“…Reaction of 4-thiocyanatomethyl-coumarins/1-aza-coumarins with alcohols has been investigated. In the case of primary and secondary alcohols, the reaction…”
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Syntheses and Crystal Structures of Three 4-((Quinolin-8-yloxy)methyl)-2H-chromen-2-one Derivatives
Published in Journal of chemical crystallography (01-12-2018)“…Three coumarin and 8-hydroxyquinoline hybrids each linked by a methylene bridge were synthesized under Pechmann cyclisation conditions and crystals were grown…”
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