Search Results - "Kulikova, L E"

Selection of progesterone derivatives specific to membrane progesterone receptors by Polikarpova, A. V., Maslakova, A. A., Levina, I. S., Kulikova, L. E., Kuznetsov, Y. V., Guseva, A. A., Shchelkunova, T. A., Zavarzin, I. V., Smirnova, O. V.

“…The search of selective agonists and antagonists of membrane progesterone receptors (mPRs) is a starting point for the study of progesterone signal…”
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Approaches to the design of selective ligands for membrane progesterone receptor alpha by Lisanova, O. V., Shchelkunova, T. A., Morozov, I. A., Rubtsov, P. M., Levina, I. S., Kulikova, L. E., Smirnov, A. N.

“…A number of progesterone derivatives were assayed in terms of their affinity for recombinant human membrane progesterone receptor alpha (mPRα) in comparison…”
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Cytotoxic activity and molecular modeling of progestins, pregna-D′-pentaranes by Scherbakov, A. M., Levina, I. S., Kulikova, L. E., Fedyushkina, I. V., Skvortsov, V. S., Veselovsky, A. V., Kuznetsov, Yu. V., Zavarzin, I. V.

“…The cytotoxic activity of synthetic progestins (pregna-D′-pentaranes II–V), full agonists of the progesterone receptor (PR), has been investigated towards…”
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Synthesis of 4-hetero-16α,17α-cyclohexanopregnanes and evaluation of their cytotoxicity against the HeLa cell line by Levina, I. S., Kulikova, L. E., Semeikin, A. V., Zavarzin, I. V.

“…The oxidation of the ring A of 16α,17α-cyclohexanoprogesterone gave 5-oxo-A-nor-3,5-secopregnan-3-oic acid. The subsequent ring A closure in the latter…”
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THE LEFT VENTRICLE DIASTOLIC FUNCTION IN PATIENTS WITH HYPERTENSION UNDER THE USE OF DIFFERENT DRUG GROUPS by Budnevskij, A. V., Ovsjannikov, E. S., Kulikova, L. E.

“…The objective: To assess the prevalence of diastolic dysfunction in patients with hypertension and preserved left ventricular ejection fraction under…”
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Agonistic and Antagonistic Effects of Progesterone Derivatives on the Transcriptional Activity of Nuclear Progesterone Receptor B in Yeast Model System by Michurina, A. O., Polikarpova, A. V., Levina, I. S., Kulikova, L. E., Zavarzin, I. V., Guseva, A. A., Morozov, I. A., Rubtsov, P. M., Smirnova, O. V., Shchelkunova, T. A.

“…Identification of progesterone selective agonists and antagonists that act through one of the nuclear progesterone receptor isoforms is of particular…”
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The size and/or configuration of the cycloalkane D′ ring in pentacyclic progesterone derivatives are crucial for their high-affinity binding to a protein in addition to progesterone receptor in rat uterine cytosol by Smirnov, Alexander N, Pokrovskaya, Elena V, Kogteva, Galina S, Shevchenko, Valery P, Levina, Inna S, Kulikova, Lidiya E, Kamernitzky, Alexey V

“…[ 3H]labeled progesterone and a number of its 16α,17α-cycloalkano derivatives with an additional three to six-membered D′ ring were investigated for mutual…”
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Synthesis and Cytostatic Activity of some Pregna-D′-Pentaranes on HeLa Cell Culture by Semeikin, A. V., Fedotcheva, T. A., Levina, I. S., Kulikova, L. E., Zavarzin, I. V., Tikhonov, D. A., Kareva, E. N., Shimanovskii, N. L.

“…The effects of nine new pregnane steroids containing substituents in the 16α,17α- and/or 3-, 6-, and 19-positions of the steroid framework on the viability of…”
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synthesis of O-substituted 3-oximes of 6α -methyl-16α,17α-cyclohexanopregn-4-ene-3,20-diones tritium-labeled in the 1,2-position by Shevchenko, V. P, Nagaev, I. Yu, Levina, I. S, Kulikova, L. E, Myasoedov, N. F, Kamernitzky, A. V

“…1,2-Tritium-labeled 3-(O-carboxypropyl)- and 3-(O-carbomethoxypropyl)-oximes of 6α-methyl-16α,17α-cyclohexanopregn-4-ene-3,20-diones were obtained by the…”
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The synthesis of O-substituted 3-oximes of 6alpha-methyl-16alpha,17alpha-cyclohexanopregn-4-ene-3,20-dione tritium-labeled in 1 and 2 positions by Shevchenko, V P, Nagaev, I Iu, Levina, I S, Kulikova, L E, Miasoedov, N F, Kamernitzkiĭ, A V

“…1,2-Tritium-labeled 3-(O-carboxypropyl)- and 3-(O-carbomethoxypropyl)-oximes of 6alpha-methyl-16alpha,17alpha-cyclohexanopregn-4-ene-3,20-diones were obtained…”
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Synthesis of 19-substituted steroids of the 16α,17α-cyclohexanopregnane series and study of their interactions with rat uterine cytosol and blood serum proteins by Levina, I. S., Kulikova, L. E., Kamernitsky, A. V., Pokrovskaya, E. V., Smirnov, A. N.

“…New 16α,17α-cyclohexanopregnanes (pregna-D′6-pentaranes) containing alkyl or heteroatomic substituents in position 19, namely, 19-methylidene-, 19-methyl-,…”
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Substituted 16alpha,17alpha-cyclohexanopregnanes: the anionic oxy-Cope rearrangement of 3beta-tert-butyldimethylsilyloxy-19-hydroxy-19-vinyl-16alpha,17alpha-cyclohexapregn-5-en-20-one by Levina, I S, Kulikova, L E, Shashkov, A S, Galakhova, T N, Kamernitskiĭ, A V

“…(19R)- and (19S)-tert-Butyldimethylsilyl (TBS) ethers of 19-hydroxy-19-vinyl-16alpha,17alpha-cyclohexanopregn-5-en-20-ones were synthesized. These compounds…”
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Synthesis of tritium-labelled biologically active analogues of progesterone by selective hydrogenation of 16α,17α-cyclohex-3′-en-pregna-1,4-dien-3,20-dione by Shevchenko, V. P., Nagaev, I. Yu, Potapova, A. V., Myasoedov, N. F., Kamernitsky, A. V., Levina, I. S., Kulikova, L. E., Smirnov, A. N.

“…The procedure of selective hydrogenation with gaseous tritium of 16α,17α‐cyclohex‐3′‐en‐pregna‐1,4‐dien‐3,20‐dione (St0) has been elaborated, and isotropically…”
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Structural Features of Pregna-D′-pentaranes Determining Their Interaction with Three Rat Proteins by Pokrovskaya, E. V., Levina, I. S., Kulikova, L. E., Kamernitsky, A. V., Smirnov, A. N.

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Pregna-D'-pentaranes - a new class of active gestagenes by Kamernitzky, A V, Levina, I S, Kulikova, L E, Ignatov, V N, Korkhov, V V, Nikitina, G V, Terekhina, A I

“…A new class of modified progesterones with an additional ring in the 16 alpha , 17 alpha-position (pregna-D'-pentaranes) are described. Compounds containing 4-…”
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Reaction of 5β,6β-epoxy-16α,17α-cyclohexapregnane with methylmagnesium iodide by Levina, I. S., Kulikova, L. E., Kachala, V. V., Khemchyan, L. L.

“…On treatment with methylmagnesium iodide, 3β-acetoxy-5β,6β-epoxy-16α,17α-cyclo-hexapregnan-20-one undergoes 3- O -deacetylation along with the opening of the…”
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Synthesis, structutre and biological activity of substituted [16α,17α]cyclopropapregn-4-ene-3,20-diones by Levina, I. S., Kulikova, L. E., Shulishov, E. V., Tomilov, Yu. V., Smirnov, A. N.

“…Aryldiazomethanes generated by vacuum thermolysis of arenecarbaldehyde tosylhydrazone sodium salts react stereospecifically with 16-dehydropregnenolone…”
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Cytotoxic activity and molecular modeling of progestins - pregna-D'-pentarans by Scherbakov, A M, Levina, I S, Kulikova, L E, Fedyushkina, I V, Skvortsov, V S, Veselovsky, A V, Kuznetsov, Y V, Zavarzin, I V

“…The cytotoxic activity of synthetic progestins (pregna-D'-pentaranes) II-V full agonists of the progesterone receptor (PR) for PR-positive and PR-negative…”
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Bioactive 5-reduced 16 alpha,17 alpha-cyclohexanoprogesterone derivatives weakly interact with proteins of the soluble uterine fraction by Smirnov, A N, Pokrovskaya, E V, Levina, I S, Kulikova, L E, Kamernitskii, A V, Shevchenko, V P

“…We studied competitive activities of 16 alpha,17 alpha-cyclohexano-5 alpha- and 5 beta-dihydroprogesterone in replacing(3)H-progesterone and(3)H-16 alpha,17…”
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Synthesis of [3H]-cycloalkanoprogesterones (pregna-d'-pentaranes) and study of their interaction with a progesterone receptor by Kamernitsky, A. V., Levina, I. S., Kulikova, L. E., Galakhova, T. N., Shevchenko, V. P., Nagaev, I. Yu, Myasoedov, N. F., Smirnov, A. N., Pokrovskaya, E. V., Schelkunova, T. A.

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