Search Results - "Kulik, Michael J"

Regulation of CTCF loop formation during pancreatic cell differentiation by Lyu, Xiaowen, Rowley, M. Jordan, Kulik, Michael J., Dalton, Stephen, Corces, Victor G.

“…Transcription reprogramming during cell differentiation involves targeting enhancers to genes responsible for establishment of cell fates. To understand the…”
Get full text

Directed differentiation of human pluripotent cells to neural crest stem cells by Menendez, Laura, Kulik, Michael J, Page, Austin T, Park, Sarah S, Lauderdale, James D, Cunningham, Michael L, Dalton, Stephen

“…Multipotent neural crest stem cells (NCSCs) have the potential to generate a wide range of cell types including melanocytes; peripheral neurons; and smooth…”
Get full text

Dynamic changes in replication timing and gene expression during lineage specification of human pluripotent stem cells by Rivera-Mulia, Juan Carlos, Buckley, Quinton, Sasaki, Takayo, Zimmerman, Jared, Didier, Ruth A, Nazor, Kristopher, Loring, Jeanne F, Lian, Zheng, Weissman, Sherman, Robins, Allan J, Schulz, Thomas C, Menendez, Laura, Kulik, Michael J, Dalton, Stephen, Gabr, Haitham, Kahveci, Tamer, Gilbert, David M

“…Duplication of the genome in mammalian cells occurs in a defined temporal order referred to as its replication-timing (RT) program. RT changes dynamically…”
Get full text

Activin A Efficiently Specifies Definitive Endoderm from Human Embryonic Stem Cells Only When Phosphatidylinositol 3‐Kinase Signaling Is Suppressed by McLean, Amanda B., D'Amour, Kevin A., Jones, Karen L., Krishnamoorthy, Malini, Kulik, Michael J., Reynolds, David M., Sheppard, Alan M., Liu, Huiqing, Xu, Ying, Baetge, Emmanuel E., Dalton, Stephen

“…Human ESCs (hESCs) respond to signals that determine their pluripotency, proliferation, survival, and differentiation status. In this report, we demonstrate…”
Get full text

Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages by Gasimli, Leyla, Hickey, Anne Marie, Yang, Bo, Li, Guoyun, dela Rosa, Mitche, Nairn, Alison V, Kulik, Michael J, Dordick, Jonathan S, Moremen, Kelley W, Dalton, Stephen, Linhardt, Robert J

“…Proteoglycans are found on the cell surface and in the extracellular matrix, and serve as prime sites for interaction with signaling molecules. Proteoglycans…”
Get full text

Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment by Dileep, Vishnu, Wilson, Korey A., Marchal, Claire, Lyu, Xiaowen, Zhao, Peiyao A., Li, Ben, Poulet, Axel, Bartlett, Daniel A., Rivera-Mulia, Juan Carlos, Qin, Zhaohui S., Robins, Allan J., Schulz, Thomas C., Kulik, Michael J., McCord, Rachel Patton, Dekker, Job, Dalton, Stephen, Corces, Victor G., Gilbert, David M.

“…The temporal order of DNA replication is regulated during development and is highly correlated with gene expression, histone modifications and 3D genome…”
Get full text

Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 synthase deficiency variants by Dookwah, Michelle, Wagner, Shannon K, Ishihara, Mayumi, Yu, Seok-Ho, Ulrichs, Heidi, Kulik, Michael J, Zeltner, Nadja, Dalton, Stephen, Strauss, Kevin A, Aoki, Kazuhiro, Steet, Richard, Tiemeyer, Michael

“…Abstract GM3 Synthase Deficiency (GM3SD) is a neurodevelopmental disorder resulting from pathogenic variants in the ST3GAL5 gene, which encodes GM3 synthase, a…”
Get full text

Allogeneic Cell Therapy for the Treatment of Liver Disease by Ludlow, John W., Bruce, Andrew T., Kulik, Michael J., Meheux, Sonya O., McCoy, Darell W., Asfeldt, Thomas M.

“…The scarcity of human organs available for transplantation is clearly evident. Efforts to maximize the use of available organs and to increase the number of…”
Get full text

Cloning and characterization of cDNAs encoding two forms of avian stem cell factor by Petitte, James N., Kulik, Michael J.

“…Stem cell factor (SCF), also known as Steel factor, is a transmembrane cytokine involved in several developmental processes and the ligand for the receptor…”
Get full text

EXPRESSION AND PURIFICATION OF BIOLOGICALLY ACTIVE RECOMBINANT QUAIL STEM CELL FACTOR IN E. COLI by D'Costa, Susan, Kulik, Michael J., Petitte, James N.

“…Stem cell factor (SCF) is a multifunctional cytokine involved in hematopoiesis, melanogenesis and gametogenesis. Previous studies have demonstrated that avian…”
Get full text