Search Results - "Kulig, Katherine M."

Liver cell therapy and tissue engineering for transplantation by Vacanti, Joseph P., MD, Kulig, Katherine M

“…Abstract Liver transplantation remains the only definitive treatment for liver failure and is available to only a tiny fraction of patients with end-stage…”
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Successful creation of tissue-engineered autologous auricular cartilage in an immunocompetent large animal model by Bichara, David A, Pomerantseva, Irina, Zhao, Xing, Zhou, Libin, Kulig, Katherine M, Tseng, Alan, Kimura, Anya M, Johnson, Matthew A, Vacanti, Joseph P, Randolph, Mark A, Sundback, Cathryn A

“…Tissue-engineered cartilage has historically been an attractive alternative treatment option for auricular reconstruction. However, the ability to reliably…”
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In vitro evaluation of decellularized ECM-derived surgical scaffold biomaterials by Luo, Xiao, Kulig, Katherine M, Finkelstein, Eric B, Nicholson, Margaret F, Liu, Xiang-Hong, Goldman, Scott M, Vacanti, Joseph P, Grottkau, Brian E, Pomerantseva, Irina, Sundback, Cathryn A, Neville, Craig M

“…Decellularized extracellular matrix (ECM) biomaterials are increasingly used in regenerative medicine for abdominal tissue repair. Emerging ECM biomaterials…”
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Three-Dimensional Microfluidic Tissue-Engineering Scaffolds Using a Flexible Biodegradable Polymer by Bettinger, C. J., Weinberg, E. J., Kulig, K. M., Vacanti, J. P., Wang, Y., Borenstein, J. T., Langer, R.

“…Three‐dimensional microfluidic networks using a flexible biodegradable polymer have been fabricated using modified microfabrication processes tailored…”
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In vitro analysis of a hepatic device with intrinsic microvascular-based channels by Carraro, Amedeo, Hsu, Wen-Ming, Kulig, Katherine M., Cheung, Wing S., Miller, Mark L., Weinberg, Eli J., Swart, Eric F., Kaazempur-Mofrad, Mohammad, Borenstein, Jeffrey T., Vacanti, Joseph P., Neville, Craig

“…A novel microfluidics-based bilayer device with a discrete parenchymal chamber modeled upon hepatic organ architecture is described. The microfluidics network…”
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Biologic properties of surgical scaffold materials derived from dermal ECM by Kulig, Katherine M, Luo, Xiao, Finkelstein, Eric B, Liu, Xiang-Hong, Goldman, Scott M, Sundback, Cathryn A, Vacanti, Joseph P, Neville, Craig M

“…Abstract Surgical scaffold materials manufactured from donor human or animal tissue are increasingly being used to promote soft tissue repair and regeneration…”
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Engineering ear constructs with a composite scaffold to maintain dimensions by Zhou, Libin, Pomerantseva, Irina, Bassett, Erik K, Bowley, Chris M, Zhao, Xing, Bichara, David A, Kulig, Katherine M, Vacanti, Joseph P, Randolph, Mark A, Sundback, Cathryn A

“…Engineered cartilage composed of a patient's own cells can become a feasible option for auricular reconstruction. However, distortion and shrinkage of…”
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Conditions for seeding and promoting neo-auricular cartilage formation in a fibrous collagen scaffold by Zhao, Xing, Bichara, David A, Zhou, Libin, Kulig, Katherine M, Tseng, Alan, Bowley, Christopher M, Vacanti, Joseph P, Pomerantseva, Irina, Sundback, Cathryn A, Randolph, Mark A

“…Abstract Background Carved autologous costal cartilage and porous polyethylene implants (Medpor) are the most common approaches for total ear reconstruction,…”
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Liver-Assist Device With a Microfluidics-Based Vascular Bed in an Animal Model by HSU, Wen-Ming, CARRARO, Amedeo, VACANTI, Joseph P, NEVILLE, Craig, KULIG, Katherine M, MILLER, Mark L, KAAZEMPUR-MOFRAD, Mohammad, WEINBERG, Eli, ENTABI, Fateh, ALBADAWI, Hassan, WATKINS, Michael T, BORENSTEIN, Jeffrey T

“…This study evaluates a novel liver-assist device platform with a microfluidics-modeled vascular network in a femoral arteriovenous shunt in rats. Liver-assist…”
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Hepatic tissue engineering by Kulig, Katherine M., Vacanti, Joseph P.

“…Fulminant hepatic failure (FHF) attributes to rising medical cost and accounts for many deaths each year in the United States. Currently, the only solution is…”
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A bilayer small diameter in vitro vascular model for evaluation of drug induced vascular injury by Hoganson, David M., Finkelstein, Eric B., Owens, Gwen E., Hsiao, James C., Eng, Kurt Y., Kulig, Katherine M., Kim, Ernest S., Kniazeva, Tatiana, Pomerantseva, Irina, Neville, Craig M., Turk, James R., Fermini, Bernard, Borenstein, Jeffrey T., Vacanti, Joseph P.

“…In pre-clinical safety studies, drug-induced vascular injury (DIVI) is defined as an adverse response to a drug characterized by degenerative and hyperplastic…”
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Ovine Model for Auricular Reconstruction: Porous Polyethylene Implants by Hohman, Marc H., Lindsay, Robin W., Pomerantseva, Irina, Bichara, David A., Zhao, Xing, Johnson, Matthew, Kulig, Katherine M., Sundback, Cathryn A., Randolph, Mark A., Vacanti, Joseph P., Cheney, Mack L., Hadlock, Theresa A.

“…Objectives: We developed a large animal model for auricular reconstruction with engineered cartilage frameworks and evaluated the performance of porous…”
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Nanofabricated collagen-inspired synthetic elastomers for primary rat hepatocyte culture by Bettinger, Christopher J, Kulig, Katherine M, Vacanti, Joseph P, Langer, Robert, Borenstein, Jeffrey T

“…Synthetic substrates that mimic the properties of extracellular matrix proteins hold significant promise for use in systems designed for tissue engineering…”
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A Nanofiber Membrane Maintains the Quiescent Phenotype of Hepatic Stellate Cells by Eda, Hiroyuki, Kulig, Katherine M., Steiner, Toni A., Shimada, Hideaki, Patel, Krupali, Park, Eric, Kim, Ernest S., Borenstein, Jeffrey T., Neville, Craig M., Keller, Bradley T.

“…Background Hepatic stellate cells (HSC) play a major role in the progression of liver fibrosis. Aim The aim of our study was to investigate whether rat HSC…”
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