Search Results - "Kulhanek, Jaromir"
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Formulation of hyaluronan grafted with dodecanoic acid as a potential ophthalmic treatment
Published in Carbohydrate polymers (15-10-2020)“…[Display omitted] •Amphiphilic hyaluronan (HAC12) can be used for artificial tears formulation.•The molecular weight and degree of substitution of HAC12 play…”
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Retinoic acid grafted to hyaluronan for skin delivery: Synthesis, stability studies, and biological evaluation
Published in Carbohydrate polymers (01-03-2020)“…[Display omitted] •The stability of HA-ATRA is a function of the degree of substitution.•The use of morin increased the photostability of HA-ATRA.•HA-ATRA…”
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Lauroyl hyaluronan films for local drug delivery: Preparation and factors influencing the release of small molecules
Published in International journal of pharmaceutics (25-10-2021)“…[Display omitted] •Safe and biodegradable films from lauroyl hyaluronan for local drug delivery.•Films successfully loaded with both hydrophobic and…”
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Antimicrobial nanofibrous mats with controllable drug release produced from hydrophobized hyaluronan
Published in Carbohydrate polymers (01-09-2021)“…Due to their large active surface, high loading efficiency, and tunable dissolution profiles, nanofibrous mats are often cited as promising drug carriers or…”
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Influence of serum albumin on intracellular delivery of drug-loaded hyaluronan polymeric micelles
Published in International journal of pharmaceutics (10-09-2016)“…[Display omitted] Polymeric micelles are attractive drug delivery systems for intravenously administered nonpolar drugs. Although physical parameters like…”
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Insight into the Lubrication and Adhesion Properties of Hyaluronan for Ocular Drug Delivery
Published in Biomolecules (Basel, Switzerland) (30-09-2021)“…Hyaluronan (HA) is widely used for eye drops as lubricant to counteract dry eye disease. High and low molecular weight HA are currently used in ophthalmology…”
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Linolenic acid grafted hyaluronan: Process development, structural characterization, biological assessing, and stability studies
Published in Carbohydrate polymers (05-11-2016)“…•Amphiphilic hyaluronan was prepared by linking alpha linolenic acid (ALA).•Thermostability of linolenyl-grafted-HA was influenced by the way of drying.•Spray…”
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Effects of emulsion, dispersion, and blend electrospinning on hyaluronic acid nanofibers with incorporated antiseptics
Published in International journal of biological macromolecules (01-01-2022)“…Nanofibrous materials are used in drug delivery as carriers of active ingredients. These can be incorporated into the materials with various electrospinning…”
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Hyaluronic Acid Fibres in Solid Phase Peptide Synthesis — Their Properties, Morphology and Stability
Published in Fibers and polymers (01-12-2020)“…Different methods and materials can be used for peptide synthesis. One of the most common approaches is synthesis on a solid phase. In this paper, we describe…”
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Water-insoluble thin films from palmitoyl hyaluronan with tunable properties
Published in Carbohydrate polymers (25-06-2016)“…•We developed water-insoluble thin films from palmitoyl hyaluronan (pHA).•Insolubility by improved pHA synthesis: higher substitution degrees now…”
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Synthesis and Physicochemical Characterization of Undecylenic Acid Grafted to Hyaluronan for Encapsulation of Antioxidants and Chemical Crosslinking
Published in Polymers (24-12-2019)“…In this work, a new amphiphilic derivative made of 10-undecylenic acid grafted to hyaluronan was prepared by mixed anhydrides. The reaction conditions were…”
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Retinoic Acid Grafted to Hyaluronic Acid Activates Retinoid Gene Expression and Removes Cholesterol from Cellular Membranes
Published in Biomolecules (Basel, Switzerland) (25-01-2022)“…All-trans-retinoic acid (atRA) is a potent ligand that regulates gene expression and is used to treat several skin disorders. Hyaluronic acid (HA) was…”
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Electrospinning of Fibrous Layers Containing an Antibacterial Chlorhexidine/Kaolinite Composite
Published in ACS applied bio materials (18-05-2020)“…The aim of this study was to prepare self-supporting homogeneous nano/microfibrous layers with a content of the clay mineral kaolinite and kaolinite modified…”
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14
Cryptococcus laurentii Extracellular Biopolymer Production for Application in Wound Management
Published in Applied biochemistry and biotechnology (01-10-2014)“…Cryptococcus laurentii growth and extracellular polysaccharide (EPS) production in bioreactor were studied. Biomass yield 14.3 g/L and EPS synthesis 4.3 g/L in…”
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Characterization of Hyaluronan-Degrading Enzymes from Yeasts
Published in Applied biochemistry and biotechnology (01-10-2015)“…Hyaluronidases (HAases) from yeasts were characterized for the first time. The study elucidated that hyaluronate 4-glycanohydrolase and hyaluronan (HA) lyase…”
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Fabrication of biodegradable textile scaffold based on hydrophobized hyaluronic acid
Published in International journal of biological macromolecules (01-02-2017)“…In this work, we report on the preparation of a novel biodegradable textile scaffold made of palmitoyl-hyaluronan (palHA). Monofilament fibres of palHA with a…”
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Preparation, characterization and cytotoxicity studies of a novel bioconjugate hyaluronan and a-linolenic acid
Published in Frontiers in bioengineering and biotechnology (2016)“…Abstract only…”
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In situ formed aldehyde-modified hyaluronic acid hydrogel with polyelectrolyte complexes of aldehyde-modified chondroitin sulfate and gelatin: An approach for minocycline delivery
Published in Carbohydrate polymers (01-11-2024)“…Polysaccharides like hyaluronan (HA) and chondroitin sulfate (CS) are native of the brain's extracellular matrix crucial for myelination and brain maturation…”
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