Search Results - "Kulemzin, S. V."

shp-2 gene knockout upregulates CAR-driven cytotoxicity of YT NK cells by Subrakova, V G, Kulemzin, S V, Belovezhets, T N, Chikaev, A N, Chikaev, N A, Koval, O A, Gorchakov, A A, Taranin, A V

“…In Russia, cancer is the second leading cause of death following cardiovascular diseases. Adoptive transfer of NK cells is a promising approach to fight…”
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Combination of Oncolytic Virotherapy and CAR T/NK Cell Therapy for the Treatment of Cancer by Kochneva, G. V., Sivolobova, G. F., Tkacheva, A. V., Gorchakov, A. A., Kulemzin, S. V.

“…Multiple lines of evidence indicate that CAR-T cell based therapy and oncolytic virotherapy display robust performance in both immunocompetent and…”
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Enhanced Natural Killers with CISH and B2M Gene Knockouts Reveal Increased Cytotoxicity in Glioblastoma Primary Cultures by Yusubalieva, G. M., Dashinimaev, E. B., Gorchakov, A. A., Kulemzin, S. V., Brovkina, O. A., Kalinkin, A. A., Vinokurov, A. G., Shirmanova, M. V., Taranin, A. V., Baklaushev, V. P.

“…In an experimental study using the CRISPR/Cas9 system, “enhanced” NK cell lines with knockout of CISH , the gene for the CIS protein (a negative regulator of…”
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CAR T-cell therapy: Balance of efficacy and safety by Kulemzin, S. V., Kuznetsova, V. V., Mamonkin, M., Taranin, A. V., Gorchakov, A. A.

“…Early results from clinical trials of autologous chimeric antigen receptor (CAR)-expressing T cells for the therapy of B-cell malignancies have encouraged…”
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Engineering Chimeric Antigen Receptors by Kulemzin, S V, Kuznetsova, V V, Mamonkin, M, Taranin, A V, Gorchakov, A A

“…Chimeric antigen receptors (CARs) are recombinant protein molecules that redirect cytotoxic lymphocytes toward malignant and other target cells. The high…”
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Modular lentiviral vector system for chimeric antigen receptor design optimization by Kulemzin, S. V., Chikaev, N. A., Volkova, O. Y., Kuznetsova, V. V., Taranin, A. V., Gorchakov, A. A.

“…The article reports the development of a collection of lentiviral vector constructs enabling time-efficient production and testing of different variants of…”
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Comparative analysis of lactaptin activity when produced in bacterial or eukaryotic expression systems by Koval, O. A., Volkova, O. Y., Gorchakov, A. A., Kulemzin, S. V., Tkachenko, A. V., Nushtaeva, A. A., Kuligina, E. V., Richter, V. A., Taranin, A. V.

“…Despite the multitude of anticancer cytostatic drugs available to oncologists today, most of such drugs have serious side effects that may preclude their use…”
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Evaluation of virus-neutralizing antibody level after novel coronavirus infection COVID-19: development of an instant assay assessing protective antibodies using a pseudovirus-based reaction by Funtikov, Andrey A., Litvinova, N. A., Zuev, Evgenii V., Kulemzin, Sergey V., Shukurov, Rachim R.

“…The continued emergence of SARS-CoV-2 variants with immune evasion properties of concern, such as Delta (B.1.617.2) and Omicron (B.1.1.529), calls into…”
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Combination of Oncolytic Virotherapy and CAR T/NK Cell Therapy for the Treatment of Cancer by Kochneva, G V, Sivolobova, G F, Tkacheva, A V, Gorchakov, A A, Kulemzin, S V

“…Multiple lines of evidence indicate that CAR-T cell based therapy and oncolytic virotherapy display robust performance in both immunocompetent and…”
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COVID-19. Etiology, pathogenesis, diagnosis and treatment by Baklaushev, Vladimir, Kulemzin, Sergey V, Gorchakov, Andrey A., Sotnikova, Anna G., Averyanov, Alexandr V.

“…COVID-19 is a new epidemic infectious disease characterized by a relatively high contagiousness and the likelihood of life-threatening complications in the…”
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FCRLA is a resident endoplasmic reticulum protein that associates with intracellular Igs, IgM, IgG and IgA by Santiago, Teresa, Kulemzin, Sergei V, Reshetnikova, Evdokia S, Chikaev, Nikolai A, Volkova, Olga Y, Mechetina, Ludmila V, Zhao, Meina, Davis, Randall S, Taranin, Alexander V, Najakshin, Alexander M, Hendershot, Linda M, Burrows, Peter D

“…Fc receptor-like A (FCRLA) is an unusual member of the extended Fc receptor family. FCRLA has homology to receptors for the Fc portion of Ig (FCR) and to other…”
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