Search Results - "Kulasekara, Hemantha D."

The Acinetobacter baumannii Mla system and glycerophospholipid transport to the outer membrane by Kamischke, Cassandra, Fan, Junping, Bergeron, Julien, Kulasekara, Hemantha D, Dalebroux, Zachary D, Burrell, Anika, Kollman, Justin M, Miller, Samuel I

“…The outer membrane (OM) of Gram-negative bacteria serves as a selective permeability barrier that allows entry of essential nutrients while excluding toxic…”
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Evidence for induction of integron-based antibiotic resistance by the SOS response in a clinical setting by Hocquet, Didier, Llanes, Catherine, Thouverez, Michelle, Kulasekara, Hemantha D, Bertrand, Xavier, Plésiat, Patrick, Mazel, Didier, Miller, Samuel I

“…Bacterial resistance to β-lactams may rely on acquired β-lactamases encoded by class 1 integron-borne genes. Rearrangement of integron cassette arrays is…”
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Asymmetrical Distribution of the Second Messenger c-di-GMP upon Bacterial Cell Division by Christen, Matthias, Kulasekara, Hemantha D, Christen, Beat, Kulasekara, Bridget R, Hoffman, Lucas R, Miller, Samuel I

“…The bacterial second messenger cyclic diguanosine monophosphate (c-di-GMP) regulates cellular motility and the synthesis of organelles and molecules that…”
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A broadly distributed toxin family mediates contact-dependent antagonism between gram-positive bacteria by Whitney, John C, Peterson, S Brook, Kim, Jungyun, Pazos, Manuel, Verster, Adrian J, Radey, Matthew C, Kulasekara, Hemantha D, Ching, Mary Q, Bullen, Nathan P, Bryant, Diane, Goo, Young Ah, Surette, Michael G, Borenstein, Elhanan, Vollmer, Waldemar, Mougous, Joseph D

“…The Firmicutes are a phylum of bacteria that dominate numerous polymicrobial habitats of importance to human health and industry. Although these communities…”
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In vivo protein interaction network analysis reveals porin-localized antibiotic inactivation in Acinetobacter baumannii strain AB5075 by Wu, Xia, Chavez, Juan D., Schweppe, Devin K., Zheng, Chunxiang, Weisbrod, Chad R., Eng, Jimmy K., Murali, Ananya, Lee, Samuel A., Ramage, Elizabeth, Gallagher, Larry A., Kulasekara, Hemantha D., Edrozo, Mauna E., Kamischke, Cassandra N., Brittnacher, Mitchell J., Miller, Samuel I., Singh, Pradeep K., Manoil, Colin, Bruce, James E.

“…The nosocomial pathogen Acinetobacter baumannii is a frequent cause of hospital-acquired infections worldwide and is a challenge for treatment due to its…”
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Pyomelanin-producing Pseudomonas aeruginosa selected during chronic infections have a large chromosomal deletion which confers resistance to pyocins by Hocquet, Didier, Petitjean, Marie, Rohmer, Laurence, Valot, Benoît, Kulasekara, Hemantha D., Bedel, Elodie, Bertrand, Xavier, Plésiat, Patrick, Köhler, Thilo, Pantel, Alix, Jacobs, Michael A., Hoffman, Lucas R., Miller, Samuel I.

“…Summary When bacterial lineages make the transition from free‐living to permanent association with hosts, they can undergo massive gene losses, for which the…”
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c-di-GMP heterogeneity is generated by the chemotaxis machinery to regulate flagellar motility by Kulasekara, Bridget R, Kamischke, Cassandra, Kulasekara, Hemantha D, Christen, Matthias, Wiggins, Paul A, Miller, Samuel I

“…Individual cell heterogeneity is commonly observed within populations, although its molecular basis is largely unknown. Previously, using FRET-based…”
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Nutrient availability as a mechanism for selection of antibiotic tolerant Pseudomonas aeruginosa within the CF airway by Hoffman, Lucas R, Richardson, Anthony R, Houston, Laura S, Kulasekara, Hemantha D, Martens-Habbena, Willm, Klausen, Mikkel, Burns, Jane L, Stahl, David A, Hassett, Daniel J, Fang, Ferric C, Miller, Samuel I

“…Microbes are subjected to selective pressures during chronic infections of host tissues. Pseudomonas aeruginosa isolates with inactivating mutations in the…”
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Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients by D'Argenio, David A, Wu, Manhong, Hoffman, Lucas R, Kulasekara, Hemantha D, Déziel, Eric, Smith, Eric E, Nguyen, Hai, Ernst, Robert K, Larson Freeman, Theodore J, Spencer, David H, Brittnacher, Mitchell, Hayden, Hillary S, Selgrade, Sara, Klausen, Mikkel, Goodlett, David R, Burns, Jane L, Ramsey, Bonnie W, Miller, Samuel I

“…The opportunistic pathogen Pseudomonas aeruginosa undergoes genetic change during chronic airway infection of cystic fibrosis (CF) patients. One common change…”
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A novel two‐component system controls the expression of Pseudomonas aeruginosa fimbrial cup genes by Kulasekara, Hemantha D., Ventre, Isabelle, Kulasekara, Bridget R., Lazdunski, Andrée, Filloux, Alain, Lory, Stephen

“…Summary Biofilm formation by the opportunistic pathogen Pseudomonas aeruginosa requires the expression of a number of surface adhesive components. The…”
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Discovery of coordinately regulated pathways that provide innate protection against interbacterial antagonism by Ting, See-Yeun, LaCourse, Kaitlyn D, Ledvina, Hannah E, Zhang, Rutan, Radey, Matthew C, Kulasekara, Hemantha D, Somavanshi, Rahul, Bertolli, Savannah K, Gallagher, Larry A, Kim, Jennifer, Penewit, Kelsi M, Salipante, Stephen J, Xu, Libin, Peterson, S Brook, Mougous, Joseph D

“…Bacterial survival is fraught with antagonism, including that deriving from viruses and competing bacterial cells. It is now appreciated that bacteria mount…”
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Acquisition and Evolution of the exoU Locus in Pseudomonas aeruginosa by KULASEKARA, Bridget R, KULASEKARA, Hemantha D, WOLFGANG, Matthew C, STEVENS, Lisa, FRANK, Dara W, LORY, Stephen

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Transposon mutagenesis by Kulasekara, Hemantha D

“…Transposon-based mutagenesis of bacterial genomes is a powerful method to identify genetic elements that control specific phenotypes. The most frequently used…”
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The bacterial second messenger c‐di‐GMP: mechanisms of signalling by Mills, Erez, Pultz, Ingrid S., Kulasekara, Hemantha D., Miller, Samuel I.

“…Summary Cyclic‐di‐GMP (c‐di‐GMP) regulates many important bacterial processes. Freely diffusible intracellular c‐di‐GMP is determined by the action of…”
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Precursor Acquisition Independent From Ion Count: How to Dive Deeper into the Proteomics Ocean by Panchaud, Alexandre, Scherl, Alexander, Shaffer, Scott A, von Haller, Priska D, Kulasekara, Hemantha D, Miller, Samuel I, Goodlett, David R

“…Data-dependent precursor ion selection is widely used in shotgun proteomics to profile the protein components of complex samples. Although very popular, this…”
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Conditional toxicity and synergy drive diversity among antibacterial effectors by LaCourse, Kaitlyn D., Peterson, S. Brook, Kulasekara, Hemantha D., Radey, Matthew C., Kim, Jungyun, Mougous, Joseph D.

“…Bacteria in polymicrobial habitats contend with a persistent barrage of competitors, often under rapidly changing environmental conditions 1 . The direct…”
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Pseudomonas aeruginosa In Vitro Phenotypes Distinguish Cystic Fibrosis Infection Stages and Outcomes by MAYER-HAMBLETT, Nicole, ROSENFELD, Margaret, KULASEKARA, Bridget R, KHAN, Umer, BURNS, Jane L, MILLER, Samuel I, HOFFMAN, Lucas R, GIBSON, Ronald L, RAMSEY, Bonnie W, KULASEKARA, Hemantha D, RETSCH-BOGART, George Z, MORGAN, Wayne, WOLTER, Daniel J, POPE, Christopher E, HOUSTON, Laura S

“…Pseudomonas aeruginosa undergoes phenotypic changes during cystic fibrosis (CF) lung infection. Although mucoidy is traditionally associated with transition to…”
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Pseudomonas aeruginosa lasR mutants are associated with cystic fibrosis lung disease progression by Hoffman, Lucas R, Kulasekara, Hemantha D, Emerson, Julia, Houston, Laura S, Burns, Jane L, Ramsey, Bonnie W, Miller, Samuel I

“…Abstract Background Pseudomonas aeruginosa with mutations in the transcriptional regulator LasR chronically infect the airways of people with cystic fibrosis…”
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Pseudomonas aeruginosa Phenotypes Associated With Eradication Failure in Children With Cystic Fibrosis by Mayer-Hamblett, Nicole, Ramsey, Bonnie W., Kulasekara, Hemantha D., Wolter, Daniel J., Houston, Laura S., Pope, Christopher E., Kulasekara, Bridget R., Armbruster, Catherine R., Burns, Jane L., Retsch-Bogart, George, Rosenfeld, Margaret, Gibson, Ronald L., Miller, Samuel I., Khan, Umer, Hoffman, Lucas R.

“…Background. Pseudomonas aeruginosa is a key respiratory pathogen in people with cystic fibrosis (CF). Due to its association with lung disease progression,…”
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Identification of Small‐Molecule Modulators of Diguanylate Cyclase by FRET‐Based High‐Throughput Screening by Christen, Matthias, Kamischke, Cassandra, Kulasekara, Hemantha D., Olivas, Kathleen C., Kulasekara, Bridget R., Christen, Beat, Kline, Toni, Miller, Samuel I.

“…The bacterial second messenger cyclic diguanosine monophosphate (c‐di‐GMP) is a key regulator of cellular motility, the cell cycle, and biofilm formation with…”
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