Search Results - "Kulagin, Alexander D"

Efficacy and safety of nivolumab combined with brentuximab vedotin after nivolumab monotherapy failure in patients with relapsed and refractory classic Hodgkin lymphoma by Fedorova, Liudmila V., Lepik, Kirill V., Volkov, Nikita P., Kotselyabina, Polina V., Borzenkova, Evgenia S., Popova, Marina O., Beynarovich, Anastasia V., Baykov, Vadim V., Kozlov, Andrey V., Moiseev, Ivan S., Mikhailova, Natalia B., Kulagin, Alexander D.

“…Objectives Therapy of patients with relapsed and refractory classic Hodgkin lymphoma (r/r cHL) after PD-1 inhibitors failure remains an unresolved issue. The…”
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Incidence of Common Herpesviruses in Colonic Mucosal Biopsies Following Hematopoietic Stem Cell Transplantation by Goloshchapov, Oleg V, Shvetsov, Alexander N, Chukhlovin, Alexey B, Spiridonova, Anna A, Vladovskaya, Maria D, Zubarovskaya, Ludmila S, Kulagin, Alexander D

“…Intestinal complications are common after allogeneic hematopoietic stem cell transplantation (allo-HSCT). However, only scarce data concern herpesvirus…”
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Time-Dependent Shifts in Intestinal Bacteriome, Klebsiella Colonization and Incidence of Antibiotic-Resistance Genes after Allogeneic Hematopoietic Stem Cell Transplantation by Goloshchapov, Oleg V, Chukhlovin, Alexey B, Polev, Dmitrii E, Eismont, Yury A, Bug, Dmitry S, Kusakin, Alexey V, Kosarev, Oleg V, Klementeva, Ruslana V, Gostev, Vladimir V, Ageevets, Vladimir A, Volkov, Nikita P, Ipatova, Anastasia S, Moiseev, Ivan S, Spiridonova, Anna A, Sidorenko, Sergey V, Kulagin, Alexander D

“…Dose-intensive cytostatic therapy and antibiotic treatment in allogeneic hematopoietic stem cell transplantation (allo-HSCT) cause severe abnormalities in a…”
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A Phase 2 Study of Nivolumab Using a Fixed Dose of 40 mg (Nivo40) in Patients With Relapsed/Refractory Hodgkin Lymphoma by Lepik, Kirill V., Fedorova, Liudmila V., Kondakova, Elena V., Zalyalov, Yuri R., Babenko, Elena V., Lepik, Elena E., Kotselyabina, Polina V., Beynarovich, Anastasia V., Popova, Marina O., Volkov, Nikita P., Stelmakh, Lilia V., Baykov, Vadim V., Moiseev, Ivan S., Mikhailova, Natalia B., Kulagin, Alexander D., Afanasyev, Boris V.

“…Supplemental Digital Content is available in the text The introduction of nivolumab has changed the landscape of relapsed/refractory classical Hodgkin lymphoma…”
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Pharmacokinetic and pharmacodynamic effects of ravulizumab and eculizumab on complement component 5 in adults with paroxysmal nocturnal haemoglobinuria: results of two phase 3 randomised, multicentre studies by Peffault de Latour, Régis, Brodsky, Robert A., Ortiz, Stephan, Risitano, Antonio M., Jang, Jun H., Hillmen, Peter, Kulagin, Alexander D., Kulasekararaj, Austin G., Rottinghaus, Scott T., Aguzzi, Rasha, Gao, Xiang, Wells, Richard A., Szer, Jeff

“…Ravulizumab, a novel long‐acting complement component 5 (C5) inhibitor administered every 8 weeks (q8w), was non‐inferior to eculizumab for all efficacy…”
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Impact of prior COVID‐19 infection on allogeneic hematopoietic stem cell transplantation outcomes by Siniaev, Aleksandr, Popova, Marina, Rogacheva, Yulia, Ianbukhtina, Valeria, Kulagin, Egor, Vladovskaya, Maria, Bondarenko, Sergey, Moiseev, Ivan, Kulagin, Alexander D.

“…There are limited data on outcomes of allogeneic hematopoietic stem cell transplantation (allo‐HSCT) in recipients with prior COVID‐19 infection. This…”
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Second haploidentical stem cell transplantation (HAPLO-SCT2) after relapse from a first HAPLO-SCT in acute leukaemia—a study on behalf of the Acute Leukaemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (EBMT) by Filippini Velázquez, Giuliano, Labopin, Myriam, Tischer, Johanna, Raiola, Anna Maria, Angelucci, Emanuele, Kulagin, Alexander D., Galieni, Piero, Bermúdez, Arancha, Bulabois, Claude-Eric, Kröger, Nicolaus, Díez-Martín, José Luis, Kwon, Mi, Nagler, Arnon, Schmid, Christoph, Ciceri, Fabio, Mohty, Mohamad

“…For patients with acute myeloid and lymphoblastic leukaemia (AML/ALL) lacking a matched sibling or unrelated donor, haploidentical stem cell transplantation…”
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Effect of eculizumab treatment in patients with paroxysmal nocturnal hemoglobinuria with or without high disease activity: Real‐world findings from the International Paroxysmal Nocturnal Hemoglobinuria Registry by Höchsmann, Britta, Fontbrune, Flore Sicre, Lee, Jong Wook, Kulagin, Alexander D., Hillmen, Peter, Wilson, Amanda, Marantz, Jing L., Schrezenmeier, Hubert

“…Background The effects of eculizumab treatment in paroxysmal nocturnal hemoglobinuria (PNH) patients with or without high‐disease activity (HDA), defined by…”
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Relationship of paroxysmal nocturnal hemoglobinuria (PNH) granulocyte clone size to disease burden and risk of major vascular events in untreated patients: results from the International PNH Registry by Dingli, David, Maciejewski, Jaroslaw P., Larratt, Loree, Go, Ronald S., Höchsmann, Britta, Zu, Ke, Gustovic, Philippe, Kulagin, Alexander D.

“…Paroxysmal nocturnal hemoglobinuria (PNH) is caused by acquired gene mutations resulting in deficiency of glycosylphosphatidylinositol (GPI)–anchored…”
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Randomized multicenter noninferiority phase III clinical trial of the first biosimilar of eculizumab by Kulagin, Alexander D., Ptushkin, Vadim V., Lukina, Elena A., Davydkin, Igor L., Korobkin, Alexander V., Shamrai, Vladimir S., Konstantinova, Tatyana S., Kaporskaya, Tatyana S., Mitina, Tatyana A., Ksenzova, Tatyana I., Zuev, Evgeny V., Markova, Oksana A., Gapchenko, Elena V., Kudlay, Dmitry A.

“…Currently, eculizumab is the main effective treatment for paroxysmal nocturnal hemoglobinuria (PNH). The aim of this randomized multicenter noninferiority…”
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Safety, Feasibility, and Advantages of Oral Microbiota Transplantation: The First Clinical Case by Goloshchapov, Oleg V, Chukhlovin, Alexey B, Bug, Dmitrii S, Polev, Dmitriy E, Kosarev, Oleg V, Klementeva, Ruslana V, Izmailova, Ekaterina A, Kazantsev, Ilya V, Khalipskaia, Margarita S, Goloshchapova, Мaria О, Yudintseva, Olesya S, Barkhatov, Ildar M, Petukhova, Natalia V, Zubarovskaya, Ludmila S, Kulagin, Alexander D, Moiseev, Ivan S

“…The pilot clinical study presented demonstrates the possibility, safety, and effectiveness of oral microbiota transplantation from a healthy donor to a patient…”
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Pregnancy in paroxysmal nocturnal hemoglobinuria: from survival to life by Vinogradova, Maria A., Kulagin, Alexander D., Shmakov, Roman G.

“…Background. Pregnancy in paroxysmal nocturnal hemoglobinuria (PNH) patients has historically been a high-risk situation. The combination of chronic…”
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Conversion from calcineurin inhibitors to sirolimus in transplant‐associated thrombotic microangiopathy by Kanunnikov, Mikhail M., Rakhmanova, Zhemal Z., Levkovsky, Nikita V., Vafina, Aliya I., Goloshapov, Oleg V., Shchegoleva, Tatiana S., Vlasova, Julia J., Paina, Olesya V., Morozova, Elena V., Zubarovskaya, Ludmilla, Kulagin, Alexander D., Moiseev, Ivan

“…Transplant‐associated thrombotic microangiopathy (TA‐TMA) is a specific complication of allogeneic hematopoietic cell transplantation with a multifactorial…”
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Cerebrovascular complications of hematopoetic stem cell transplantation in patients with hematologic malignancies by Polushin, Alexey Yu, Skiba, Iaroslav B., Bakin, Evgeny A., Vladovskaya, Maria D., Yakovleva, Victoria A., Moiseev, Ivan S., Yanishevskiy, Stanislav N., Voznyuk, Igor A., Kulagin, Alexander D.

“…Introduction. Modern transplantation and biological therapy methods are associated with a wide range of adverse events and complications. Incidence and variety…”
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Stroke before a haematopoietic stem cell transplantation is a potential risk factor for poor response to therapy in patients with blood cancer by Polushin, Alexey Yu, Skiba, Iaroslav B., Bakin, Evgeny A., Vladovskaya, Maria D., Moiseev, Ivan S., Voznyuk, Igor A., Kulagin, Alexander D.

“…Introduction. More than 50,000 haematopoietic stem cell transplantations (HSCTs) are performed worldwide each year to treat malignant blood cancers, solid…”
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High-dose immunosuppressive therapy with autologous hematopoietic stem cell transplantation as a treatment option in multiple sclerosis by Shevchenko, Yury L, Novik, Andrei A, Kuznetsov, Aleksey N, Afanasiev, Boris V, Lisukov, Igor A, Kozlov, Vladimir A, Rykavicin, Oleg A, Ionova, Tatyana I, Melnichenko, Vladimir Y, Fedorenko, Denis A, Kulagin, Alexander D, Shamanski, Sergei V, Ivanov, Roman A, Gorodokin, Gary

“…High-dose immunosuppressive therapy (HDIT) with autologous hematopoietic stem cell transplantation (auto-HSCT) is a new and promising approach to the treatment…”
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An inter-laboratory comparison of PNH clone detection by high-sensitivity flow cytometry in a Russian cohort by Sipol, Alexandra A, Babenko, Elena V, Borisov, Vyacheslav I, Naumova, Elena V, Boyakova, Elena V, Yakunin, Dimitry I, Glazanova, Tatyana V, Chubukina, Zhanna V, Pronkina, Natalya V, Popov, Alexander M, Saveliev, Leonid I, Lugovskaya, Svetlana A, Lisukov, Igor A, Kulagin, Alexander D, Illingworth, Andrea J

“…Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal stem cell disorder characterized by partial or absolute deficiency of…”
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Predictive Model and Factors of Relapse after Allogeneic Stem Cell Transplantation in Adults with Ph-Positive Acute Lymphoblastic Leukemia by Afanaseva, Kseniia S., Bakin, Evgeny A., Pirogova, Olga V., Morozova, Elena V., Barkhatov, Ildar M., Smirnova, Anna G., Bondarenko, Sergey N., Moiseev, Ivan S., Kulagin, Alexander D.

“…Background: Relapses after allo-HSCT remain an unsolved problem in Ph-positive acute lymphoblastic leukemia (ALL) patients, especially in patients with…”
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Long-Term Outcome of Second Allogeneic Stem Cell Transplantation (HSCT2) for Primary Graft Failure in Patients with Acute Leukemia in Remission: A Study on Behalf of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation by Nagler, Arnon, Labopin, Myriam, Kulagin, Alexander D., Velardi, Andrea, Sanz, Jaime, Labussière-Wallet, Hélène, Potter, Victoria, Kuball, Jurgen, Sica, Simona, Parovichnikova, Elena N., Bethge, Wolfgang, Leleu, Xavier, Platzbecker, Uwe, Stölzel, Friedrich, Ciceri, Fabio, Mohty, Mohamad

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A Second Haploidentical Stem Cell Transplantation (HAPLO-SCT2) after Relapse from First Haplo-SCT Is Feasible and Produces Results That Are Comparable to Data Reported after Second SCT in an HLA-Matched Setting - a Study on Behalf of the Acute Leukaemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (EBMT) by Filippini Velazquez, Giuliano, Labopin, Myriam, Tischer, Johanna, Angelucci, Emanuele, Kulagin, Alexander D., Galieni, Piero, Bermúdez, Arancha, Bulabois, Claude-Eric, Kröger, Nicolaus, Díez-Martin, José Luis, Nagler, Arnon, Schmid, Christoph, Ciceri, Fabio, Mohty, Mohamad

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