Search Results - "Kukic, Ira"

Zinc-dependent lysosomal enlargement in TRPML1-deficient cells involves MTF-1 transcription factor and ZnT4 (Slc30a4) transporter by Kukic, Ira, Lee, Jeffrey K, Coblentz, Jessica, Kelleher, Shannon L, Kiselyov, Kirill

“…Zinc is critical for a multitude of cellular processes, including gene expression, secretion and enzymatic activities. Cellular zinc is controlled by…”
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The IN/OUT assay: a new tool to study ciliogenesis by Kukic, Ira, Rivera-Molina, Felix, Toomre, Derek

“…Nearly all cells have a primary cilia on their surface, which functions as a cellular antennae. Primary cilia assembly begins intracellularly and eventually…”
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A protocol for retrospective translational science case studies of health interventions by Dodson, Sara E, Kukic, Ira, Scholl, Linda, Pelfrey, Clara M, Trochim, William M

“…The critical processes driving successful research translation remain understudied. We describe a mixed-method case study protocol for analyzing translational…”
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Altered dynamics of a lipid raft associated protein in a kidney model of Fabry disease by Labilloy, Anatália, Youker, Robert T., Bruns, Jennifer R., Kukic, Ira, Kiselyov, Kirill, Halfter, Willi, Finegold, David, Monte, Semiramis Jamil Hadad do, Weisz, Ora A.

“…Accumulation of globotriaosylceramide (Gb3) and other neutral glycosphingolipids with galactosyl residues is the hallmark of Fabry disease, a lysosomal storage…”
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Zinc Dependent Lysosomal Enlargement in TRPML1-Deficient Cells Involves MTF1 Transcription Factor and ZnT4 (Slca4) Transporter by Kukic, Ira

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Zn2+ efflux through lysosomal exocytosis prevents Zn2+-induced toxicity by Kukic, Ira, Kelleher, Shannon L, Kiselyov, Kirill

“…Zn(2+) is an essential micronutrient and an important ionic signal whose excess, as well as scarcity, is detrimental to cells. Free cytoplasmic Zn(2+) is…”
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Zinc efflux through lysosomal exocytosis prevents zinc-induced toxicity by Kukic, Ira, Kelleher, Shannon L., Kiselyov, Kirill

“…Zinc (Zn2+) is an essential micronutrient and an important ionic signal, whose excess as well as scarcity are detrimental to cells. Free cytoplasmic Zn2+ is…”
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Unclogging the zinc sink: Examining the role of zinc trafficking in Mucolipidosis type IV and lysosomes by Kukic, Ira

“…Zinc is an essential micronutrient that regulates many cellular processes. Deficits or excessive abundance in zinc concentration have catastrophic consequences…”
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Altered dynamics of a lipid raft associated protein in a kidney model of Fabry disease by Labilloy, Anatália, Youker, Robert T., Bruns, Jennifer R., Kukic, Ira, Kiselyov, Kiril, Halfter, Willi, Finegold, David N., Monte, Semiramis Jamil Hadad do, Weisz, Ora A.

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