Search Results - "Kuitert, L M"

Clinical Immunology Review Series: An approach to the management of pulmonary disease in primary antibody deficiency by Tarzi, M.D, Grigoriadou, S, Carr, S.B, Kuitert, L.M, Longhurst, H.J

“…The sinopulmonary tract is the major site of infection in patients with primary antibody deficiency syndromes, and structural lung damage arising from repeated…”
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Leukotriene receptor antagonists: useful in acute asthma? by KUITERT, L M, BARNES, N C

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Eicosanoid mediator expression in mononuclear and polymorphonuclear cells in normal subjects and patients with atopic asthma and cystic fibrosis by Kuitert, L. M., Newton, R., Barnes, N. C., Adcock, I. M., Barnes, P. J.

“…BACKGROUND: Eicosanoids such as leukotrienes, prostaglandins, lipoxins, and 15-hydroperoxyeicosatetraenoic acid (15-HETE) cause bronchoconstriction, increased…”
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Pneumocystis carinii pneumonia as a complication of methotrexate treatment of asthma by Kuitert, L M, Harrison, A C

“…A 32 year old man with chronic severe asthma, requiring maintenance oral corticosteroids, was started on a weekly dose of methotrexate. Eleven weeks later he…”
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Effect of a novel potent platelet-activating factor antagonist, modipafant, in clinical asthma by Kuitert, L M, Angus, R M, Barnes, N C, Barnes, P J, Bone, M F, Chung, K F, Fairfax, A J, Higenbotham, T W, O'Connor, B J, Piotrowska, B

“…Platelet-activating factor (PAF), proposed as an important inflammatory mediator in asthma, reproduces several of the features of asthma, such as microvascular…”
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Beta agonists in asthma--state of the art: report on a Royal Society of Medicine seminar by Kuitert, L M

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Risk of severe life threatening asthma by Barnes, N C, Kuitert, L M

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Intravenous magnesium sulfate in acute, life-threatening asthma by Kuitert, L M, Kletchko, S L

“…Magnesium, a physiologic calcium antagonist, is known to have a direct effect on calcium uptake in smooth muscle, resulting in smooth muscle relaxation…”
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Use of a chronic disease management programme in COPD to reduce hospital admissions by Pushparajah, S, McClellan, R, Henry, A, Kuitert, L M E

“…Chronic obstructive pulmonary disease (COPD) accounts for a large number of hospital admissions and numerous interventions have attempted to reduce…”
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Outcome of untreated Mycobacterium avium-intracellulare complex infection in AIDS by Kuitert, L M, Thomas, M G, Ellis-Pegler, R B

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Antibiotic restriction policies in public hospitals by Kuitert, L M, Thomas, M G

“…We surveyed annual expenditure on antimicrobial agents and the use of antimicrobial restriction policies. Restriction policies were in use in 25 of 27 of the…”
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Drugs affecting the leukotriene pathway in asthma by Barnes, N C, Kuitert, L M

“…Drugs affecting the leukotriene pathway are emerging as a new class of asthma treatment--the first for more than 20 years. Development of these leukotriene…”
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Effect of the platelet-activating factor antagonist UK-74,505 on the early and late response to allergen by Kuitert, L M, Hui, K P, Uthayarkumar, S, Burke, W, Newland, A C, Uden, S, Barnes, N C

“…The effect of UK-74,505, a specific platelet-activating factor (PAF) antagonist, on the early (EAR) and late asthmatic response (LAR) to inhaled allergen was…”
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The lung in diabetes--yet another target organ? by Kuitert, L M E

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Cytokine induction of cytosolic phospholipase A2 and cyclooxygenase-2 mRNA is suppressed by glucocorticoids in human epithelial cells by Newton, R., Kuitert, L.M., Slater, D.M., Adcock, I.M., Barnes, P.J.

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Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA by Newton, R, Seybold, J, Kuitert, L M, Bergmann, M, Barnes, P J

“…The two cyclooxygenase (COX) isoforms convert arachidonic acid to precursor prostaglandins (PGs). Up-regulation of COX-2 is responsible for increased PG…”
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Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta by Newton, R, Kuitert, L M, Bergmann, M, Adcock, I M, Barnes, P J

“…The cyclooxygenase (COX) isoforms COX-1 and COX-2 convert arachidonic acid to prostaglandin (PG) precursors and are a limiting step in PG production…”
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Cytokine induction of cytosolic phospholipase A2 and cyclooxygenase-2 mRNA is suppressed by glucocorticoids in human epithelial cells by Newton, R, Kuitert, L M, Slater, D M, Adcock, I M, Barnes, P J

“…Prostaglandin (PG) release, which is increased in vivo by inflammatory conditions and in vitro by pro-inflammatory cytokines, is decreased by glucocorticoids…”
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