Search Results - "Kuiken, Thijs"
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Broadening the aims of avian influenza surveillance according to the One Health approach
Published in mBio (16-10-2024)“…The ongoing outbreak of the Goose/Guangdong/1/1996 (Gs/Gd) H5 lineage of highly pathogenic avian influenza (HPAI) viruses has caused higher mortality than all…”
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Is low pathogenic avian influenza virus virulent for wild waterbirds?
Published in Proceedings of the Royal Society. B, Biological sciences (22-07-2013)“…Although low pathogenic avian influenza virus (LPAIV) is traditionally considered to have adapted to its wild waterbird host to become avirulent, recent…”
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Implications of Transformative Changes for Research on Emerging Zoonoses
Published in EcoHealth (01-09-2021)Get full text
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Pathogenesis of influenza-induced acute respiratory distress syndrome
Published in The Lancet infectious diseases (2014)“…Summary Acute respiratory distress syndrome (ARDS) is a fatal complication of influenza infection. In this Review we provide an integrated model for its…”
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Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model
Published in Science (American Association for the Advancement of Science) (29-05-2020)“…The current pandemic coronavirus, severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), was recently identified in patients with an acute respiratory…”
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High-throughput sequencing reveals inbreeding depression in a natural population
Published in Proceedings of the National Academy of Sciences - PNAS (11-03-2014)“…Proxy measures of genome-wide heterozygosity based on approximately 10 microsatellites have been used to uncover heterozygosity fitness correlations (HFCs) for…”
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Pathology and virology of natural highly pathogenic avian influenza H5N8 infection in wild Common buzzards (Buteo buteo)
Published in Scientific reports (18-01-2022)“…Highly pathogenic avian influenza (HPAI) in wild birds is a major emerging disease, and a cause of increased mortality during outbreaks. The Common buzzard (…”
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Role of Endothelial Cells in the Pathogenesis of Influenza in Humans
Published in The Journal of infectious diseases (22-10-2019)Get full text
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Influenza virus damages the alveolar barrier by disrupting epithelial cell tight junctions
Published in The European respiratory journal (01-03-2016)“…A major cause of respiratory failure during influenza A virus (IAV) infection is damage to the epithelial-endothelial barrier of the pulmonary alveolus. Damage…”
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Presence of coronaviruses in the common pipistrelle (P. pipistrellus) and Nathusius´ pipistrelle (P. nathusii) in relation to landscape composition
Published in PloS one (29-11-2023)“…Changes in land use can modify habitat and roosting behaviour of bats, and therefore the transmission dynamics of viruses. Within bat roosts the density and…”
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A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection
Published in Nature communications (30-07-2021)“…SARS-CoV-2, the causative agent of COVID-19 1 , features a receptor-binding domain (RBD) for binding to the host cell ACE2 protein 1 – 6 . Neutralizing…”
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Evolution of highly pathogenic H5N1 influenza A virus in the central nervous system of ferrets
Published in PLoS pathogens (01-03-2023)“…Central nervous system (CNS) disease is the most common extra-respiratory tract complication of influenza A virus infections in humans. Remarkably, zoonotic…”
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Deaths among Wild Birds during Highly Pathogenic Avian Influenza A(H5N8) Virus Outbreak, the Netherlands
Published in Emerging infectious diseases (01-12-2017)“…During autumn-winter 2016-2017, highly pathogenic avian influenza A(H5N8) viruses caused mass die-offs among wild birds in the Netherlands. Among the ≈13,600…”
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SARS-CoV-2 Neutralizing Human Antibodies Protect Against Lower Respiratory Tract Disease in a Hamster Model
Published in The Journal of infectious diseases (15-06-2021)“…Abstract Effective clinical intervention strategies for coronavirus disease 2019 (COVID-19) are urgently needed. Although several clinical trials have…”
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Avian influenza overview December 2022 – March 2023
Published in EFSA journal (01-03-2023)“…Between 3 December 2022 and 1 March 2023 highly pathogenic avian influenza (HPAI) A(H5N1) virus, clade 2.3.4.4b, was reported in Europe in domestic (522) and…”
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Mass Mortality Caused by Highly Pathogenic Influenza A(H5N1) Virus in Sandwich Terns, the Netherlands, 2022
Published in Emerging infectious diseases (01-12-2022)“…We collected data on mass mortality in Sandwich terns (Thalasseus sandvicensis) during the 2022 breeding season in the Netherlands. Mortality was associated…”
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Distribution patterns of influenza virus receptors and viral attachment patterns in the respiratory and intestinal tracts of seven avian species
Published in Veterinary research (Paris) (10-04-2012)“…This study assessed the presence of sialic acid α-2,3 and α-2,6 linked glycan receptors in seven avian species. The respiratory and intestinal tracts of the…”
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The Potential for Respiratory Droplet-Transmissible A/H5N1 Influenza Virus to Evolve in a Mammalian Host
Published in Science (American Association for the Advancement of Science) (22-06-2012)“…Avian A/H5N1 influenza viruses pose a pandemic threat. As few as five amino acid substitutions, or four with reassortaient, might be sufficient for…”
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Avian influenza overview June – September 2022
Published in EFSA journal (01-10-2022)“…The 2021–2022 highly pathogenic avian influenza (HPAI) epidemic season is the largest HPAI epidemic so far observed in Europe, with a total of 2,467 outbreaks…”
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Adaptive pathways of zoonotic influenza viruses: From exposure to establishment in humans
Published in Vaccine (22-06-2012)“…Highlights ► Pandemic influenza viruses all have their origins in animal reservoirs. ► Adaptive changes characterize animal influenza viruses crossing species…”
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