Search Results - "Kuijpers, RWAM"
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Mast cells are major contributors to the pathophysiology of Graves’ Ophthalmopathy (GO)
Published in Journal of translational medicine (25-11-2010)“…Conclusion Mast cells are important in the pathophysiology of GO, as their numbers are increased in GO orbital tissue and their products histamine and tryptase…”
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Efficacy of adalimumab in sarcoidosis
Published in Journal of translational medicine (25-11-2010)“…From: 5th European Workshop on Immune-Mediated Inflammatory Diseases Sitges-Barcelona, Spain 1-3 December 2010 Author details 1-Dept. of Internal Medicine,…”
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3
Orbit-Infiltrating Mast Cells, Monocytes, and Macrophages Produce PDGF Isoforms that Orchestrate Orbital Fibroblast Activation in Graves' Ophthalmopathy
Published in The journal of clinical endocrinology and metabolism (01-03-2012)“…Purpose: Platelet-derived growth factors (PDGF) are regulators of fibroblast activity that may be involved in the pathophysiology of Graves' ophthalmopathy…”
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Anti-TNF-α therapy for sight threatening uveitis
Published in British journal of ophthalmology (01-05-2005)“…Aim: To describe the effect of additional treatment with anti-TNF-α therapy in a case series of 13 patients with serious sight threatening uveitis. Methods: 13…”
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Insulin-like Growth Factor-I and its Receptor in Neovascular Age-Related Macular Degeneration
Published in Investigative ophthalmology & visual science (01-05-2003)“…The insulin-like growth factor (IGF)-I protein is a growth-promoting polypeptide that can act as an angiogenic agent in the eye. The purpose of the current…”
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Somatostatin and somatostatin receptors in retinal diseases
Published in European journal of endocrinology (01-10-2000)Get full text
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Somatostatin Receptor 2A Expression in Choroidal Neovascularization Secondary to Age-Related Macular Degeneration
Published in Investigative ophthalmology & visual science (01-07-2000)“…The growth of ocular neovascularization is regulated by a balance between stimulating and inhibiting growth factors. Somatostatin affects angiogenesis by…”
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8
Adult respiratory distress syndrome after experimental intravenous γ-globulin concentrate and monocyte-reactive IgG antibodies
Published in The Lancet (British edition) (14-11-1998)Get full text
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9
Autoantibodies to photoreceptor membrane proteins and outer plexiform layer in patients with cancer‐associated retinopathy
Published in Clinical and experimental immunology (01-06-2002)“…SUMMARY Cancer‐associated retinopathy (CAR) is a paraneoplastic syndrome that is characterized by degeneration of the retina as a remote effect of cancer…”
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Experience with cyclosporine in endogenous uveitis posterior
Published in Transplantation proceedings (01-03-2004)“…Treatment with cyclosporine (CsA) has considerably improved the visual prognosis of patients suffering from endogenous posterior uveitis (EPU). However, the…”
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Treatment of Cystoid Macular Edema with Octreotide
Published in The New England journal of medicine (26-02-1998)“…To the Editor: Idiopathic cystoid macular edema is an uncommon form of retinal edema that is refractory to treatment with drugs such as acetazolamide 1 that…”
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Role of fas-ligand in age-related maculopathy not established
Published in American journal of ophthalmology (01-09-2001)“…PURPOSE: Fas-ligand expression on retinal pigment epithelium is hypothesized to have an inhibitory effect on human ocular neovascularization. METHODS: We…”
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13
Radiotherapy of exudative age-related macular degeneration; a clinical and pathologic study
Published in Graefe's archive for clinical and experimental ophthalmology (01-07-2001)“…Radiotherapy has recently been employed to treat patients with exudative macular degeneration in order to prevent severe visual loss. Radiotherapy affects the…”
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14
Single Point Mutation in Human Glycoprotein IIIa Is Associated With a New Platelet-Specific Alloantigen (Mo) Involved in Neonatal Alloimmune Thrombocytopenia
Published in Blood (01-01-1993)“…Here we describe a new platelet-specific alloantigen that was identified in a case of neonatal alloimmune thrombocytopenia. This antigen has provisionally been…”
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Adhesion molecules in iris biopsy specimens from patients with uveitis
Published in British journal of ophthalmology (01-04-1998)“…BACKGROUND/AIMS Earlier studies on intraocular tissue have demonstrated that T lymphocytes play a major role in the pathogenesis of uveitis. Adhesion molecules…”
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Maternal Genomic Neutrophil FcRIII Deficiency Leading to Neonatal Isoimmune Neutropenia
Published in Blood (15-11-1990)“…The healthy mother of a child with transient immune neutropenia was found to be “NA-null.” The mother’s neutrophils did not react with anti-NA1 and anti-NA2…”
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Apoptosis is present in the primate macula at all ages
Published in Graefe's archive for clinical and experimental ophthalmology (01-06-2000)“…It has become increasingly clear that apoptosis is a main event in photoreceptor cell death in a variety of retinal degenerations. We investigated the role of…”
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A case of severe neonatal thrombocytopenia with schizencephaly associated with anti-HPA-1b and anti-HPA-2a
Published in British journal of haematology (01-07-1994)“…We report a family with a neonate who was severely damaged by intracranial haemorrhages. These probably occurred before the 20th week of gestation. The neonate…”
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Localization of the platelet-specific HPA-2 (Ko) alloantigens on the N- terminal globular fragment of platelet glycoprotein Ib alpha
Published in Blood (01-01-1992)“…The human platelet-specific alloantigens HPA-2a and HPA-2b (= Kob and Koa) together constitute a biallelic antigen system. The HPA-2 antigens have not, to…”
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NH sub(2)-terminal globular domain of human platelet glycoprotein Ib alpha has a methionine super(145)/threonine super(145) amino acid polymorphism, which is associated with the HPA-2 (Ko) alloantigens
Published in The Journal of clinical investigation (01-01-1992)“…The glycoprotein (GP) Ib/IX complex, a prominent platelet GP complex, is the primary receptor for vWF. Previously, we have established that an antigenic…”
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