Search Results - "Kuijk, Loes"

Schistosoma mansoni Soluble Egg Antigens Induce Expression of the Negative Regulators SOCS1 and SHP1 in Human Dendritic Cells via Interaction with the Mannose Receptor by Klaver, Elsenoor J, Kuijk, Loes M, Lindhorst, Thisbe K, Cummings, Richard D, van Die, Irma

“…Schistosomiasis is a common debilitating human parasitic disease in (sub)tropical areas, however, schistosome infections can also protect against a variety of…”
Get full text

Trichuris suis-induced modulation of human dendritic cell function is glycan-mediated by Klaver, Elsenoor J., Kuijk, Loes M., Laan, Lisa C., Kringel, Helene, van Vliet, Sandra J., Bouma, Gerd, Cummings, Richard D., Kraal, Georg, van Die, Irma

“…[Display omitted] ► Trichuris suis soluble products (SP) modulate human dendritic cell (DC) function. ► Trichuris suis SP suppress LPS and TNF-α-induced…”
Get full text

Inflammasome Components NALP 1 and 3 Show Distinct but Separate Expression Profiles in Human Tissues Suggesting a Site-specific Role in the Inflammatory Response by Kummer, J. Alain, Broekhuizen, Roel, Everett, Helen, Agostini, Laetitia, Kuijk, Loes, Martinon, Fabio, van Bruggen, Robin, Tschopp, Jurg

“…Several autoinflammatory disorders such as Muckle-Wells syndrome are characterized by mutations in the NALP3/cryopyrin gene. NALP3 and NALP1 proteins can…”
Get full text

Worms to the rescue: Can worm glycans protect from autoimmune diseases? by Kuijk, Loes M., van Die, Irma

“…Autoimmune and autoinflammatory diseases represent a significant health burden, especially in Western societies. For the majority of these diseases, no cure…”
Get full text

Soluble helminth products suppress clinical signs in murine experimental autoimmune encephalomyelitis and differentially modulate human dendritic cell activation by Kuijk, Loes M., Klaver, Elsenoor J., Kooij, Gijs, van der Pol, Susanne M.A., Heijnen, Priscilla, Bruijns, Sven C.M., Kringel, Helene, Pinelli, Elena, Kraal, Georg, de Vries, Helga E., Dijkstra, Christine D., Bouma, Gerd, van Die, Irma

“…► Soluble products of T. suis and T. spiralis suppress clinical signs in murine EAE. ► Soluble products of T. suis, T. spiralis and S. mansoni modulate human…”
Get full text

Notch controls generation and function of human effector CD8+ T cells by Kuijk, Loes M., Verstege, Marleen I., Rekers, Niels V., Bruijns, Sven C., Hooijberg, Erik, Roep, Bart O., de Gruijl, Tanja D., van Kooyk, Yvette, Unger, Wendy W.J.

“…The generation of effector CD8+ T cells with lytic capacity is crucial for tumor control. Dendritic cells (DCs) provide important signals to promote naive CD8+…”
Get full text

Effective treatment of a colchicine-resistant familial Mediterranean fever patient with anakinra by Kuijk, Loes M, Govers, Anita M A P, Hofhuis, Willem J D, Frenkel, Joost

“…The patient was admitted to hospital and after confirmation of colchicine-resistant FMF, the patient and parents gave written informed consent for a trial of…”
Get full text

Statin synergizes with LPS to induce IL-1β release by THP-1 cells through activation of caspase-1 by Kuijk, Loes M., Mandey, Saskia H., Schellens, Ingrid, Waterham, Hans R., Rijkers, Ger T., Coffer, Paul J., Frenkel, Joost

“…Mevalonate kinase deficiency (MKD) is a hereditary syndrome characterized by recurring episodes of fever and inflammation. Peripheral blood mononuclear cells…”
Get full text

HMG-CoA reductase inhibition induces IL-1β release through Rac1/PI3K/PKB-dependent caspase-1 activation by Kuijk, Loes M., Beekman, Jeffrey M., Koster, Janet, Waterham, Hans R., Frenkel, Joost, Coffer, Paul J.

“…Mevalonate kinase deficiency (MKD) is an autoinflammatory disorder characterized by recurring fever episodes and results from disturbed isoprenoid…”
Get full text

A role for geranylgeranylation in interleukin‐1β secretion by Mandey, Saskia H. L., Kuijk, Loes M., Frenkel, Joost, Waterham, Hans R.

“…Objective Mevalonate kinase deficiency (MKD) is an autosomal‐recessive disorder characterized by recurring episodes of inflammation. MK catalyzes the…”
Get full text

Schistosoma mansoni Soluble Egg Antigens Induce Expression of the Negative Regulators SOCS1 and SHP1 in Human Dendritic Cells via Interaction with the Mannose Receptor: e0124089 by Klaver, Elsenoor J, Kuijk, Loes M, Lindhorst, Thisbe K, Cummings, Richard D, Die, Irma van

“…Schistosomiasis is a common debilitating human parasitic disease in (sub)tropical areas, however, schistosome infections can also protect against a variety of…”
Get full text

HMG-CoA reductase inhibition induces IL-1β release through Rac1/PBK/PKB-dependent caspase-1 activation by KUIJK, Loes M, BEEKMAN, Jeffrey M, KOSTER, Janet, WATERHAM, Hans R, FRENKEL, Joost, COFFER, Paul J

Get full text

Statin synergizes with LPS to induce IL-1beta release by THP-1 cells through activation of caspase-1 by Kuijk, Loes M, Mandey, Saskia H, Schellens, Ingrid, Waterham, Hans R, Rijkers, Ger T, Coffer, Paul J, Frenkel, Joost

“…Mevalonate kinase deficiency (MKD) is a hereditary syndrome characterized by recurring episodes of fever and inflammation. Peripheral blood mononuclear cells…”
Get full text

ANAKINRA IN COLCHICINE RESISTANT FAMILIAL MEDITERRANEAN FEVER by Frenkel, Joost, Kuijk, Loes, Hofhuis, Willem, Govers, Abita

Get full text

HMG-CoA reductase inhibition induces IL-1beta release through Rac1/PI3K/PKB-dependent caspase-1 activation by Kuijk, Loes M, Beekman, Jeffrey M, Koster, Janet, Waterham, Hans R, Frenkel, Joost, Coffer, Paul J

“…Mevalonate kinase deficiency (MKD) is an autoinflammatory disorder characterized by recurring fever episodes and results from disturbed isoprenoid…”
Get full text

A role for geranylgeranylation in interleukin-1beta secretion by Mandey, Saskia H L, Kuijk, Loes M, Frenkel, Joost, Waterham, Hans R

“…Mevalonate kinase deficiency (MKD) is an autosomal-recessive disorder characterized by recurring episodes of inflammation. MK catalyzes the phosphorylation of…”
Get full text

Effective treatment of a colchicine-resistant familial Mediterranean fever patient with anakinra by Kuijk, Loes M, Govers, Anita M A P, Frenkel, Joost, Hofhuis, Willem J D

Get full text