Search Results - "Kuick, R D"

Hsp27 expression in neuroblastoma: correlation with disease stage by Ungar, D R, Hailat, N, Strahler, J R, Kuick, R D, Brodeur, G M, Seeger, R C, Reynolds, C P, Hanash, S M

“…The 27-kd heat shock protein (Hsp27) is differentially expressed in some malignancies, including breast carcinoma, leukemia, and malignant fibrous…”
Get more information

Differential expression of Hsp27 in normal oesophagus, Barrett's metaplasia and oesophageal adenocarcinomas by SOLDES, O. S, KUICK, R. D, THOMPSON, I. A, HUGHES, S. J, ORRINGER, M. B, LANNETTONI, M. D, HANASH, S. M, BEER, D. G

“…The protein expression patterns of normal, metaplastic and malignant oesophageal tissues were analysed by two-dimensional polyacrylamide gel electrophoresis…”
Get full text

Similarity of Spontaneous Germinal and in vitro Somatic Cell Mutation Rates in Humans: Implications for Carcinogenesis and for the Role of Exogenous Factors in "Spontaneous" Germinal Mutagenesis by Kuick, R. D., Neel, J. V., Strahler, J. R., Chu, E. H. Y., Bargal, R., Fox, D. A., Hanash, S. M.

“…The rate of spontaneous mutation resulting in electrophoretic variants per cell generation in a human lymphoblastoid cell line, on the basis of experiments…”
Get full text

Estimation of Mutation Rates Based on the Analysis of Polypeptide Constituents of Cultured Human Lymphoblastoid Cells by Chu, EHY, Boehnke, M, Hanash, S. M, Kuick, R. D, Lamb, B. J, Neel, J. V, Niezgoda, W, Pivirotto, S, Sundling, G

“…A subclone of a human diploid lymphoblastoid cell line, TK-6, with consistently high cloning efficiency has been used to estimate the rates of somatic…”
Get full text

Activation of resting peripheral blood lymphocytes through the T cell receptor induces rapid phosphorylation of Op18 by Strahler, JR, Hailat, N, Lamb, BJ, Rogers, KP, Underhill, JA, Melhem, RF, Keim, DR, Zhu, X, Kuick, RD, Fox, DA

“…Op18 is a highly conserved major cytosolic phosphoprotein that has been implicated in signal transduction in a wide variety of cell types. Freshly isolated…”
Get full text

Nonrandom Distribution of Structural Mutants in Ethylnitrosourea-Treated Cultured Human Lymphoblastoid Cells by Hanash, Samir M., Boehnke, Michael, Ernest H. Y. Chu, Neel, James V., Kuick, Rork D.

“…Two-dimensional polyacrylamide gel electrophoresis has been used to detect somatic cell gene mutations altering protein structure, following ethylnitrosourea…”
Get full text

Proteomic analysis of eIF-5A in lung adenocarcinomas by Chen, Guoan, Gharib, Tarek G., Thomas, Dafydd G., Huang, Chiang-Ching, Misek, David E., Kuick, Rork D., Giordano, Thomas J., Iannettoni, Mark D., Orringer, Mark B., Hanash, Samir M., Beer, David G.

“…We examined the eIF‐5A protein expression in 93 lung adenocarcinomas and 10 uninvolved lung samples using quantitative two‐dimensional polyacrylamide gel…”
Get full text

Identification and characterization of a 19q12 amplicon in esophageal adenocarcinomas reveals Cyclin E as the best candidate gene for this amplicon by LIN LIN, PRESCOTT, Michael S, ZHOUQIN ZHU, PUJA SINGH, CHUN, Sang Y, KUICK, Rork D, HANASH, Samir M, ORRINGER, Mark B, GLOVER, Thomas W, BEER, David G

“…Genomic DNA amplification in tumors is frequently associated with an increased gene copy number of oncogenes or other cancer-related genes. We have used a…”
Get full text

Monocyte-dependent regulation of T lymphocyte activation through CD98 by Diaz, Jr, L A, Friedman, A W, He, X, Kuick, R D, Hanash, S M, Fox, D A

“…CD98 is a 125 kDa heterodimer, which is strongly expressed on the surface of activated and proliferating cells. Its expression is strikingly regulated during T…”
Get full text

Genetic p53 Deficiency Partially Rescues the Adrenocortical Dysplasia Phenotype at the Expense of Increased Tumorigenesis by Else, Tobias, Trovato, Alessia, Kim, Alex C., Wu, Yipin, Ferguson, David O., Kuick, Rork D., Lucas, Peter C., Hammer, Gary D.

“…Telomere dysfunction and shortening induce chromosomal instability and tumorigenesis. In this study, we analyze the adrenocortical dysplasia ( acd) mouse,…”
Get full text

A two-dimensional electrophoresis-related laboratory information processing system: spot matching by Kuick, R D, Skolnick, M M, Hanash, S M, Neel, J V

“…An approach for the computer-assisted analysis of two-dimensional gels has been developed as a part of our laboratory information processing system (LIPS)…”
Get more information

Podocyte hypertrophy, adaptation, and decompensation associated with glomerular enlargement and glomerulosclerosis in the aging rat : Prevention by calorie restriction by WIGGINS, Jocelyn E, GOYAL, Meera, SANDEN, Silja K, WHARRAM, Bryan L, SHEDDEN, Kerby A, MISEK, David E, KUICK, Rork D, WIGGINS, Roger C

“…Whether podocyte depletion could cause the glomerulosclerosis of aging in Fischer 344 rats at ages 2, 6, 17, and 24 mo was evaluated. Ad libitum-fed rats…”
Get full text

Somatic mutation studies in human lymphoid cells: the detectability of quantitative genetic variants in two-dimensional gels by Kuick, R D, Hanash, S M, Strahler, J R

“…The feasibility of detecting quantitative genetic variants based on a decrease in the integrated intensity of polypeptide spots in two-dimensional…”
Get more information

Nonrandom distribution of structural mutants in ethylnitrosoureatreated cultured human lymphoblastoid cells by HANASH, S. M, BOEHNKE, M, CHU, E. H. Y, NEEL, J. V, KUICK, R. D

Get full text

Nonrandom distribution of structural mutants in ethylnitrosourea-treated cultured human lymphoblastoid cells by Hanash, S M, Boehnke, M, Chu, E H, Neel, J V, Kuick, R D

“…Two-dimensional polyacrylamide gel electrophoresis has been used to detect somatic cell gene mutations altering protein structure, following ethylnitrosourea…”
Get full text