Search Results - "Kuhnell, Damaris"
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Rapid and label-free isolation of small extracellular vesicles from biofluids utilizing a novel insulator based dielectrophoretic device
Published in Lab on a chip (07-11-2019)“…Exosomes are nano-scale membrane-encapsulated vesicles produced by the majority of cells and have emerged as a rich source of biomarkers for a wide variety of…”
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Rapid purification and multiparametric characterization of circulating small extracellular vesicles utilizing a label-free lab-on-a-chip device
Published in Scientific reports (25-10-2023)“…Nano-scale extracellular vesicles are lipid-bilayer delimited particles that are naturally secreted by all cells and have emerged as valuable biomarkers for a…”
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Comparability of the small RNA secretome across human biofluids concomitantly collected from healthy adults
Published in PloS one (10-04-2020)“…Small extracellular vesicles (sEV) are nano-sized (40-150 nm), membrane-encapsulated vesicles that are released by essentially all cells into the extracellular…”
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Subcutaneous white adipose tissue expression of HuR mediates cardiac pathology via adipose tissue-derived extracellular vesicles
Published in Physiology (Bethesda, Md.) (01-05-2023)“…Abstract only Obesity is a rapidly growing epidemic worldwide, especially in the United States, and is associated with cardiovascular disease (CVD), diabetes,…”
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Comprehensive microRNA-sequencing of exosomes derived from head and neck carcinoma cells in vitro reveals common secretion profiles and potential utility as salivary biomarkers
Published in Oncotarget (10-10-2017)“…Exosomes are nano-scale, membrane encapsulated vesicles that are released by cells into the extracellular space and function as intercellular signaling vectors…”
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Balancing yield, purity and practicality: a modified differential ultracentrifugation protocol for efficient isolation of small extracellular vesicles from human serum
Published in RNA biology (02-01-2019)“…Ultracentrifugation remains the gold standard for isolation of small extracellular vesicles (sEV), particularly for cancer applications. The objective of this…”
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Abstract 1797: EGFR as a marker for head and neck squamous cell carcinoma-derived small extracellular vesicles
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Head and neck cancer will account for an estimated 61,760 new cancer cases and 13,190 cancer-related deaths in the United States in 2016, the majority…”
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Abstract 5038: Chrysotile asbestos fibers in tissue adjacent to laryngeal squamous cell carcinoma in cases with a history of occupational asbestos exposure
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Asbestos describes a group of naturally occurring fibrous silicate mineral compounds. Its use dates back thousands of years but became widespread in…”
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MicroRNA expression within neuronal-derived small extracellular vesicles in frontotemporal degeneration
Published in Medicine (Baltimore) (07-10-2022)“…MicroRNAs (miRNAs) are small non-coding RNA that are powerful regulators of gene expression and can affect the expression of hundreds of genes. miRNAs can be…”
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Abstract 26: Exosomal microRNA as salivary biomarkers of head and neck squamous cell carcinoma
Published in Clinical cancer research (01-12-2017)“…Abstract Head and neck cancer is the 10th most common cancer overall and 5th most common among men in the United States, the vast majority of which are…”
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Multimodal assessment of high-risk human papillomavirus in sinonasal squamous cell carcinoma
Published in Pathology, research and practice (01-09-2024)“…High-risk human papillomavirus (hrHPV) is an emerging risk factor for sinonasal squamous cell carcinoma (SNSCC). The goal of this study was to assess the…”
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Small extravesicular microRNA in head and neck squamous cell carcinoma and its potential as a liquid biopsy for early detection
Published in Head & neck (01-01-2023)“…Background The objective was to assess secretion of small extracellular vesicular microRNA (exo‐miRNA) in head and neck squamous cell carcinoma (HNSCC)…”
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Differential expression and prognostic value of long non‐coding RNA in HPV‐negative head and neck squamous cell carcinoma
Published in Head & neck (01-07-2018)“…Background Long non‐coding RNA (lncRNA) has emerged as a new avenue of interest due to its various biological functions in cancer. Abnormal expression of…”
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Abstract 2359: Cellular origin and functional contribution of alternatively spliced tissue factor to the malignant progression of chronic liver disease
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Background: Expression of alternatively spliced Tissue Factor (asTF), an activator of αvβ3 and α6β1 integrins, is low in the healthy liver. asTF…”
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Abstract 961: Comprehensive catalog of culture-derived exosomal microRNA cargo from 4 discrete head and neck carcinoma cell lines
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Background: Exosomes are nano-sized (40-100 nm), membrane encapsulated vesicles that are released by cells into the extracellular space and function…”
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Comprehensive mapping of the methylation landscape of 16 CpG-dense regions in oral and pharyngeal squamous cell carcinoma
Published in Epigenomics (01-07-2019)“…The goal of this study was to comprehensively interrogate and map DNA methylation across 16 CpG-dense regions previously associated with oral and pharyngeal…”
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