Search Results - "Kuhnel, Brigitte"

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    Tobacco smoking leads to extensive genome-wide changes in DNA methylation by Zeilinger, Sonja, Kühnel, Brigitte, Klopp, Norman, Baurecht, Hansjörg, Kleinschmidt, Anja, Gieger, Christian, Weidinger, Stephan, Lattka, Eva, Adamski, Jerzy, Peters, Annette, Strauch, Konstantin, Waldenberger, Melanie, Illig, Thomas

    Published in PloS one (17-05-2013)
    “…Environmental factors such as tobacco smoking may have long-lasting effects on DNA methylation patterns, which might lead to changes in gene expression and in…”
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    Are Epigenetic Factors Implicated in Chronic Widespread Pain? by Burri, Andrea, Marinova, Zoya, Robinson, Mark D, Kühnel, Brigitte, Waldenberger, Melanie, Wahl, Simone, Kunze, Sonja, Gieger, Christian, Livshits, Gregory, Williams, Frances

    Published in PloS one (10-11-2016)
    “…Chronic widespread musculoskeletal pain (CWP) is the cardinal symptom of fibromyalgia and affects about 12% of the general population. Familial aggregation of…”
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    Modeling Heterogeneity in the Genetic Architecture of Ethnically Diverse Groups Using Random Effect Interaction Models by Veturi, Yogasudha, de Los Campos, Gustavo, Yi, Nengjun, Huang, Wen, Vazquez, Ana I, Kühnel, Brigitte

    Published in Genetics (Austin) (01-04-2019)
    “…In humans, most genome-wide association studies have been conducted using data from Caucasians and many of the reported findings have not replicated in other…”
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    A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium by Devaney, Joseph, Kathiresan, Sekar, Wright, Benjamin, Mooser, Vincent, Deloukas, Panos, Stark, Klaus, Gieger, Christian, Teumer, Alexander, Illig, Thomas, Elosua, Roberto, Kühnel, Brigitte, Nauck, Matthias, Burns, Philippa, Stewart, Alexandre F R, Ouwehand, Willem H, Soranzo, Nicole, Bumpstead, Suzannah, Garner, Stephen F, Rader, Daniel J, Prokisch, Holger, Spector, Tim D, Chen, Li, Reilly, Muredach P, Schunkert, Heribert, Menzel, Stephan, Hammond, Naomi, Völker, Uwe, Greinacher, Andreas, Hall, Alistair S, Potter, Simon C, Siscovick, David S, Altshuler, David, Falchi, Mario, Burnett, Mary-Susan, Van Heel, David A, Bradley, John R, Perola, Markus, Hengstenberg, Christian, Knouff, Christopher W, Rice, Catherine M, Samani, Nilesh J, Salo, Perttu, Willenborg, Christina, Thein, Swee Lay, Melander, Olle, Schreiber, Stefan, Meisinger, Christa, Serbanovic-Canic, Jovana, Nieminen, Markku S, Salomaa, Veikko, Wells, George A, Erber, Wendy, Schwartz, Stephen M, Peltonen, Leena, Xue, Yali, Laskowski, Roman A, Watkins, Nicholas A, Ghori, Mohammed J R, Roberts, Robert, Tyler-Smith, Chris, Rendon, Augusto, Wichmann, H-Erich, Sambrook, Jennifer, König, Inke R, Gwilliam, Rhian, Surakka, Ida, Hakonarson, Hakon H, Erdmann, Jeanette, Goodall, Alison H, Thompson, John R, Döring, Angela, Epstein, Stephen E, Stephens, Jonathan, Mangino, Massimo, Völzke, Henry, Sinisalo, Juha, McPherson, Ruth, Voight, Benjamin F, O'Donnell, Christopher J, Li, Mingyao

    Published in Nature genetics (01-11-2009)
    “…Nicole Soranzo and colleagues report a meta-analysis of genome-wide association datasets identifying 22 associations to 8 clinically relevant hematological…”
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    Multiple Loci Are Associated with White Blood Cell Phenotypes: e1002113 by Nalls, Michael A, Couper, David J, Tanaka, Toshiko, Rooij, J Avan, Chen, Ming-Huei, Smith, Albert V, Toniolo, Daniela, Zakai, Neil A, Yang, Qiong, Greinacher, Andreas, Wood, Andrew R, Garcia, Melissa, Gasparini, Paolo, Liu, Yongmei, Lumley, Thomas, Folsom, Aaron R, Reiner, Alex P, Gieger, Christian, Lagou, Vasiliki, Felix, Janine F, Völzke, Henry, Gouskova, Natalia A, Biffi, Alessandro, Döring, Angela, Völker, Uwe, Chong, Sean, Wiggins, Kerri L, Rendon, Augusto, Dehghan, Abbas, Moore, Matt, Taylor, Kent, Wilson, James G, Lettre, Guillaume, Hofman, Albert, Bis, Joshua C, Pirastu, Nicola, Fox, Caroline S, Meisinger, Christa, Sambrook, Jennifer, Arepalli, Sampath, Nauck, Matthias, Prokisch, Holger, Stephens, Jonathan, Glazer, Nicole L, Cupples, L Adrienne, Okada, Yukinori, Takahashi, Atsushi, Kamatani, Yoichiro, Matsuda, Koichi, Tsunoda, Tatsuhiko, Tanaka, Toshihiro, Kubo, Michiaki, Nakamura, Yusuke, Yamamoto, Kazuhiko, Kamatani, Naoyuki, Stumvoll, Michael, Tönjes, Anke, Prokopenko, Inga, Illig, Thomas, Patel, Kushang V, Garner, Stephen F, Kuhnel, Brigitte, Mangino, Massimo, Oostra, Ben A, Thein, Swee Lay, Coresh, Josef, Wichmann, H-Erich, Menzel, Stephan, Lin, JingPing, Pistis, Giorgio, Uitterlinden, André G, Spector, Tim D, Teumer, Alexander, Eiriksdottir, Gudny, Gudnason, Vilmundur, Bandinelli, Stefania, Frayling, Timothy M, Chakravarti, Aravinda, Duijn, Cornelia Mvan, Melzer, David, Ouwehand, Willem H, Levy, Daniel, Boerwinkle, Eric, Singleton, Andrew B, Hernandez, Dena G, Longo, Dan L, Soranzo, Nicole, Witteman, Jacqueline CM, Psaty, Bruce M, Ferrucci, Luigi, Harris, Tamara B, Ganesh, Santhi K

    Published in PLoS genetics (01-06-2011)
    “…White blood cell (WBC) count is a common clinical measure from complete blood count assays, and it varies widely among healthy individuals. Total WBC count and…”
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    Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci by de Las Fuentes, Lisa, Sung, Yun Ju, Noordam, Raymond, Winkler, Thomas, Feitosa, Mary, Schwander, Karen, Bentley, Amy, Brown, Michael, Guo, Xiuqing, Manning, Alisa, Chasman, Daniel, Aschard, Hugues, Bartz, Traci, Bielak, Lawrence, Campbell, Archie, Cheng, Ching-Yu, Dorajoo, Rajkumar, Hartwig, Fernando, Horimoto, A., Li, Changwei, Li-Gao, Ruifang, Liu, Yongmei, Marten, Jonathan, Musani, Solomon, Ntalla, Ioanna, Rankinen, Tuomo, Richard, Melissa, Sim, Xueling, Smith, Albert, Tajuddin, Salman, Tayo, Bamidele, Vojinovic, Dina, Warren, Helen, Xuan, Deng, Alver, Maris, Boissel, Mathilde, Chai, Jin-Fang, Chen, Xu, Christensen, Kaare, Divers, Jasmin, Evangelou, Evangelos, Gao, Chuan, Girotto, Giorgia, Harris, Sarah, He, Meian, Hsu, Fang-Chi, Kühnel, Brigitte, Laguzzi, Federica, Li, Xiaoyin, Lyytikäinen, Leo-Pekka, Nolte, Ilja, Poveda, Alaitz, Rauramaa, Rainer, Riaz, Muhammad, Rueedi, Rico, Shu, Xiao-Ou, Snieder, Harold, Sofer, Tamar, Takeuchi, Fumihiko, Verweij, Niek, Ware, Erin, Weiss, Stefan, Yanek, Lisa, Amin, Najaf, Arking, Dan, Arnett, Donna, Bergmann, Sven, Boerwinkle, Eric, Brody, Jennifer, Broeckel, Ulrich, Brumat, Marco, Burke, Gregory, Cabrera, Claudia, Canouil, Mickaël, Chee, Miao Li, Chen, Yii-Der Ida, Cocca, Massimiliano, Connell, John, de Silva, H Janaka, de Vries, Paul, Eiriksdottir, Gudny, Faul, Jessica, Fisher, Virginia, Forrester, Terrence, Fox, Ervin, Friedlander, Yechiel, Gao, He, Gigante, Bruna, Giulianini, Franco, Gu, Chi Charles, Gu, Dongfeng, Harris, Tamara, He, Jiang, Heikkinen, Sami, Heng, Chew-Kiat, Hunt, Steven, Ikram, M Arfan, Irvin, Marguerite, Kähönen, Mika, Kavousi, Maryam

    Published in Molecular psychiatry (05-05-2020)
    “…Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low SES is a risk factor for hypertension and high blood pressure (BP). To…”
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    Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity by Kilpeläinen, Tuomas, Bentley, Amy, Noordam, Raymond, Sung, Yun Ju, Schwander, Karen, Winkler, Thomas, Jakupović, Hermina, Chasman, Daniel, Manning, Alisa, Ntalla, Ioanna, Aschard, Hugues, Brown, Michael, de Las Fuentes, Lisa, Franceschini, Nora, Guo, Xiuqing, Vojinovic, Dina, Aslibekyan, Stella, Feitosa, Mary, Kho, Minjung, Musani, Solomon, Richard, Melissa, Wang, Heming, Wang, Zhe, Bartz, Traci, Bielak, Lawrence, Campbell, Archie, Dorajoo, Rajkumar, Fisher, Virginia, Hartwig, Fernando, Horimoto, Andrea, Li, Changwei, Lohman, Kurt, Marten, Jonathan, Sim, Xueling, Smith, Albert, Tajuddin, Salman, Alver, Maris, Amini, Marzyeh, Boissel, Mathilde, Chai, Jin Fang, Chen, Xu, Divers, Jasmin, Evangelou, Evangelos, Gao, Chuan, Graff, Mariaelisa, Harris, Sarah, He, Meian, Hsu, Fang-Chi, Jackson, Anne, Zhao, Jing Hua, Kraja, Aldi, Kühnel, Brigitte, Laguzzi, Federica, Lyytikäinen, Leo-Pekka, Nolte, Ilja, Rauramaa, Rainer, Riaz, Muhammad, Robino, Antonietta, Rueedi, Rico, Stringham, Heather, Takeuchi, Fumihiko, van Der Most, Peter, Varga, Tibor, Verweij, Niek, Ware, Erin, Wen, Wanqing, Li, Xiaoyin, Yanek, Lisa, Amin, Najaf, Arnett, Donna, Boerwinkle, Eric, Brumat, Marco, Cade, Brian, Canouil, Mickaël, Chen, Yii-Der Ida, Concas, Maria Pina, Connell, John, de Mutsert, Renée, de Silva, H Janaka, de Vries, Paul, Demirkan, Ayşe, Ding, Jingzhong, Eaton, Charles, Faul, Jessica, Friedlander, Yechiel, Gabriel, Kelley, Ghanbari, Mohsen, Giulianini, Franco, Gu, Chi Charles, Gu, Dongfeng, Harris, Tamara, He, Jiang, Heikkinen, Sami, Heng, Chew-Kiat, Hunt, Steven, Ikram, M Arfan, Jonas, Jost, Koh, Woon-Puay, Komulainen, Pirjo, Krieger, Jose

    Published in Nature communications (01-12-2019)
    “…Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects…”
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