Search Results - "Kuhn, Uwe"
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Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33
Published in Genes & development (01-11-2014)“…Cleavage and polyadenylation specificity factor (CPSF) is the central component of the 3' processing machinery for polyadenylated mRNAs in metazoans: CPSF…”
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The nuclear poly(A) binding protein of mammals, but not of fission yeast, participates in mRNA polyadenylation
Published in RNA (Cambridge) (01-04-2017)“…The nuclear poly(A) binding protein (PABPN1) has been suggested, on the basis of biochemical evidence, to play a role in mRNA polyadenylation by strongly…”
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Molecular dynamics simulation of the surface tension of aqueous sodium chloride: from dilute to highly supersaturated solutions and molten salt
Published in Atmospheric chemistry and physics (04-12-2018)“…Sodium chloride (NaCl) is one of the key components of atmospheric aerosols. The surface tension of aqueous NaCl solution (σNaCl,sol) and its concentration…”
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Emission of nitrous acid from soil and biological soil crusts represents an important source of HONO in the remote atmosphere in Cyprus
Published in Atmospheric chemistry and physics (23-01-2018)“…Soil and biological soil crusts can emit nitrous acid (HONO) and nitric oxide (NO). The terrestrial ground surface in arid and semiarid regions is anticipated…”
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Low Hygroscopicity of Newly Formed Particles on the North China Plain and Its Implications for Nanoparticle Growth
Published in Geophysical research letters (28-07-2024)“…The growth of newly formed particles through new particle formation (NPF) contributes a significant fraction to the cloud condensation nuclei, yet the driving…”
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Executive performance of depressed suicide attempters: the role of suicidal ideation
Published in European archives of psychiatry and clinical neuroscience (01-10-2008)“…Objective Suicidal ideation has been related to cognitive rigidity whereas suicidal behaviour itself was associated with specific executive deficits. Yet it…”
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Net ecosystem fluxes of isoprene over tropical South America inferred from Global Ozone Monitoring Experiment (GOME) observations of HCHO columns
Published in Journal of Geophysical Research - Atmospheres (27-10-2008)“…We estimate isoprene emissions over tropical South America during 1997–2001 using column measurements of formaldehyde (HCHO) from the Global Ozone Monitoring…”
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5-HT2A receptor density is decreased in the at-risk mental state
Published in Psychopharmacologia (01-01-2008)“…Rationale Current perspectives on the pathophysiology of schizophrenia direct attention to serotonergic (serotonin, 5-HT) dysregulation in the prodrome or…”
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Stimulation of poly(A) polymerase through a direct interaction with the nuclear poly(A) binding protein allosterically regulated by RNA
Published in The EMBO journal (15-07-2003)“…During polyadenylation of mRNA precursors in metazoan cells, poly(A) polymerase is stimulated by the nuclear poly(A) binding protein PABPN1. We report that…”
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Volatile organic compound emissions in relation to plant carbon fixation and the terrestrial carbon budget
Published in Global biogeochemical cycles (01-12-2002)“…A substantial amount of carbon is emitted by terrestrial vegetation as biogenic volatile organic compounds (VOC), which contributes to the oxidative capacity…”
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Hofmeister Salts and Potential Therapeutic Compounds Accelerate in Vitro Fibril Formation of the N-Terminal Domain of PABPN1 Containing a Disease-Causing Alanine Extension
Published in Biochemistry (Easton) (19-02-2008)“…The analysis of modulation of fibril formation helps to understand the mechanism of fibrillation processes besides opening routes for therapeutic intervention…”
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Patterns of CO2 exchange in biological soil crusts of successional age
Published in Soil biology & biochemistry (01-07-2000)Get full text
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13
Financial Constraints and Moral Hazard: The Case of Franchising
Published in The Journal of political economy (01-12-2017)“…Financial constraints are considered an important impediment to growth for small businesses. We study theoretically and empirically the relationship between…”
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Communication, Renegotiation, and the Scope for Collusion
Published in American economic journal. Microeconomics (01-05-2014)“…We study the effect of communication in an experimental game where cooperation is consistent with equilibrium play if players share an understanding that…”
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Reconstitution of 3' end processing of mammalian pre-mRNA reveals a central role of RBBP6
Published in Genes & development (01-02-2022)“…The 3' ends of almost all eukaryotic mRNAs are generated in an essential two-step processing reaction: endonucleolytic cleavage of an extended precursor…”
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StavroX—A Software for Analyzing Crosslinked Products in Protein Interaction Studies
Published in Journal of the American Society for Mass Spectrometry (01-01-2012)“…Chemical crosslinking in combination with mass spectrometry has matured into an alternative approach to derive low-resolution structural information of…”
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The Poly(A)-Binding Protein Nuclear 1 Suppresses Alternative Cleavage and Polyadenylation Sites
Published in Cell (27-04-2012)“…Alternative cleavage and polyadenylation (APA) is emerging as an important layer of gene regulation. Factors controlling APA are largely unknown. We developed…”
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Leveraging Monopoly Power by Degrading Interoperability: Theory and Evidence from Computer Markets
Published in Economica (London) (01-10-2018)“…When will a monopolist have incentives to leverage her/his market power in a primary market to foreclose competition in a complementary market by degrading…”
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Behavioral sources of the demand for carbon offsets: an experimental study
Published in Experimental economics : a journal of the Economic Science Association (01-09-2019)“…Voluntary carbon markets present firms and individuals with the opportunity to offset all or part of their carbon footprints. We report on a controlled…”
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Impaired Sensorimotor Gating of the Acoustic Startle Response in the Prodrome of Schizophrenia
Published in Biological psychiatry (1969) (01-11-2008)“…Background Schizophrenia patients exhibit impairment in prepulse inhibition (PPI) of the acoustic startle response (ASR), which is commonly interpreted as a…”
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