Search Results - "Kuhn, Tanja"

Conserved patterns of protein interaction in multiple species by Sharan, R, Suthram, S, Kelley, R.M, Kuhn, T, McCuine, S, Uetz, P, Sittler, T, Karp, R.M, Ideker, T

“…To elucidate cellular machinery on a global scale, we performed a multiple comparison of the recently available protein-protein interaction networks of…”
Get full text

E96V Mutation in the Kdelr3 Gene Is Associated with Type 2 Diabetes Susceptibility in Obese NZO Mice by Altenhofen, Delsi, Khuong, Jenny Minh-An, Kuhn, Tanja, Lebek, Sandra, Görigk, Sarah, Kaiser, Katharina, Binsch, Christian, Griess, Kerstin, Knebel, Birgit, Belgardt, Bengt-Frederik, Cames, Sandra, Eickelschulte, Samaneh, Stermann, Torben, Rasche, Axel, Herwig, Ralf, Weiss, Jürgen, Vogel, Heike, Schürmann, Annette, Chadt, Alexandra, Al-Hasani, Hadi

“…Type 2 diabetes (T2D) represents a multifactorial metabolic disease with a strong genetic predisposition. Despite elaborate efforts in identifying the genetic…”
Get full text

Protein-binding microarray analysis of tumor suppressor AP2α target gene specificity by Kerschgens, Jan, Renaud, Stéphanie, Schütz, Frédéric, Grasso, Luigino, Egener-Kuhn, Tanja, Delaloye, Jean-François, Lehr, Hans-Anton, Vogel, Horst, Mermod, Nicolas

“…Cheap and massively parallel methods to assess the DNA-binding specificity of transcription factors are actively sought, given their prominent regulatory role…”
Get full text

Nudix hydrolase NUDT19 regulates mitochondrial function and ATP production in murine hepatocytes by Görigk, Sarah, Ouwens, D. Margriet, Kuhn, Tanja, Altenhofen, Delsi, Binsch, Christian, Damen, Mareike, Khuong, Jenny Minh-An, Kaiser, Katharina, Knebel, Birgit, Vogel, Heike, Schürmann, Annette, Chadt, Alexandra, Al-Hasani, Hadi

“…Changes in intracellular CoA levels are known to contribute to the development of non-alcoholic fatty liver disease (NAFLD) in type 2 diabetes (T2D) in human…”
Get full text

Comparative genomic analyses of multiple backcross mouse populations suggest SGCG as a novel potential obesity-modifier gene by Kuhn, Tanja, Kaiser, Katharina, Lebek, Sandra, Altenhofen, Delsi, Knebel, Birgit, Herwig, Ralf, Rasche, Axel, Pelligra, Angela, Görigk, Sarah, Khuong, Jenny Minh-An, Vogel, Heike, Schürmann, Annette, Blüher, Matthias, Chadt, Alexandra, Al-Hasani, Hadi

“…Abstract To nominate novel disease genes for obesity and type 2 diabetes (T2D), we recently generated two mouse backcross populations of the T2D-susceptible…”
Get full text

Protein-binding microarrays: probing disease markers at the interface of proteomics and genomics by Kerschgens, Jan, Egener-Kuhn, Tanja, Mermod, Nicolas

“…DNA-binding proteins mediate a variety of crucial molecular functions, such as transcriptional regulation and chromosome maintenance, replication and repair,…”
Get full text

Protein-Binding Microarray Analysis of Tumor Suppressor AP2[alpha] Target Gene Specificity by Kerschgens, Jan, Renaud, Stéphanie, Schütz, Frédéric, Grasso, Luigino, Egener-Kuhn, Tanja, Delaloye, Jean-François, Lehr, Hans-Anton, Vogel, Horst, Mermod, Nicolas

“…Cheap and massively parallel methods to assess the DNA-binding specificity of transcription factors are actively sought, given their prominent regulatory role…”
Get full text