Search Results - "Kuhn, Rainer R"

Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis by Dev, Kumlesh K, Mullershausen, Florian, Mattes, Henri, Kuhn, Rainer R, Bilbe, Graeme, Hoyer, Daniel, Mir, Anis

“…Multiple sclerosis (MS) is an autoimmune, neurological disability with unknown etiology. The current therapies available for MS work by an immunomodulatory…”
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LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice by HERZIG, Martin C, KOLLY, Carine, SCHNELL, Christian R, MUELLER, Matthias, KINZEL, Bernd, GREVOT, Armelle, BOLOGNANI, Federico, STIRN, Martina, KUHN, Rainer R, KAUPMANN, Klemens, VAN DER PUTTEN, P. Herman, ROVELLI, Giorgio, PERSOHN, Elke, SHIMSHEK, Derya R, THEIL, Diethilde, SCHWEIZER, Tatjana, HAFNER, Thomas, STEMMELEN, Christine, TROXLER, Thomas J, SCHMID, Peter, DANNER, Simone

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Fragments of HdhQ150 mutant huntingtin form a soluble oligomer pool that declines with aggregate deposition upon aging by Marcellin, David, Abramowski, Dorothee, Young, Douglas, Richter, Jens, Weiss, Andreas, Marcel, Audrey, Maassen, Julia, Kauffmann, Muriel, Bibel, Miriam, Shimshek, Derya R, Faull, Richard L M, Bates, Gillian P, Kuhn, Rainer R, Van der Putten, P Herman, Schmid, Peter, Lotz, Gregor P

“…Cleavage of the full-length mutant huntingtin (mhtt) protein into smaller, soluble aggregation-prone mhtt fragments appears to be a key process in the…”
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LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice by Herzig, Martin C., Kolly, Carine, Persohn, Elke, Theil, Diethilde, Schweizer, Tatjana, Hafner, Thomas, Stemmelen, Christine, Troxler, Thomas J., Schmid, Peter, Danner, Simone, Schnell, Christian R., Mueller, Matthias, Kinzel, Bernd, Grevot, Armelle, Bolognani, Federico, Stirn, Martina, Kuhn, Rainer R., Kaupmann, Klemens, van der Putten, P. Herman, Rovelli, Giorgio, Shimshek, Derya R.

“…Mutations in leucine-rich repeat kinase 2 (LRRK2) cause late-onset Parkinson's disease (PD), but the underlying pathophysiological mechanisms and the normal…”
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