Search Results - "Kuhn, L.A."

Dimensionality reduction using genetic algorithms by Raymer, M.L., Punch, W.F., Goodman, E.D., Kuhn, L.A., Jain, A.K.

“…Pattern recognition generally requires that objects be described in terms of a set of measurable features. The selection and quality of the features…”
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Reference values for maximum respiratory pressures in patients with type 2 diabetes mellitus by Caitano Fontela, P, Kuhn, L.A, Winkelmann, E.R

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Knowledge discovery in medical and biological datasets using a hybrid Bayes classifier/evolutionary algorithm by Raymer, M.L., Doom, T.E., Kuhn, L.A., Punch, W.F.

“…A key element of bioinformatics research is the extraction of meaningful information from large experimental data sets. Various approaches, including…”
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Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors by CHIA-PING CHANG, LAZAR, C. S, WILEY, H. S, GILL, G. N, WALSH, B. J, KOMURO, M, COLLAWN, J. F, KUHN, L. A, TAINER, J. A, TROWBRIDGE, I. S, FARQUHAR, M. G, ROSENFELD, M. G

“…Ligand-induced internalization of epidermal growth factor (EGF) receptors via a high affinity saturable pathway requires sequences located in the carboxyl…”
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accessory subunit of mtDNA polymerase shares structural homology with aminoacyl-tRNA synthetases: implications for a dual role as a primer recognition factor and processivity clamp by Fan, L, Sanschagrin, P.C, Kaguni, L.S, Kuhn, L.A

“…The accessory subunit of the heterodimeric mtDNA polymerase (pol(gamma)) from Drosophila embryos is required to maintain the structural integrity or catalytic…”
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Identification of mimotope peptides which bind to the mycotoxin deoxynivalenol-specific monoclonal antibody by Yuan, Q, Pestka, J.J, Hespenheide, B.M, Kuhn, L.A, Linz, L.E, Hart, P

“…Monoclonal antibody 6F5 (mAb 6F5), which recognizes the mycotoxin deoxynivalenol (DON) (vomitoxin), was used to select for peptides that mimic the mycotoxin by…”
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The interdependence of protein surface topography and bound water molecules revealed by surface accessibility and fractal density measures by Kuhn, L A, Siani, M A, Pique, M E, Fisher, C L, Getzoff, E D, Tainer, J A

“…To characterize water binding to proteins, which is fundamental to protein folding, stability and activity, the relationships of 10,837 bound water positions…”
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Prediction of the Active-Site Structure and NAD+ Binding in SQD1, a Protein Essential for Sulfolipid Biosynthesis in Arabidopsis by Essigmann, Bernd, Hespenheide, Brandon M, Kuhn, Leslie A, Benning, Christoph

“…Sulfolipids of photosynthetic bacteria and plants are characterized by their unique sulfoquinovose headgroup, a derivative of glucose in which the 6-hydroxyl…”
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Transplanted LDL and mannose‐6‐phosphate receptor internalization signals promote high‐efficiency endocytosis of the transferrin receptor by Collawn, J.F., Kuhn, L.A., Liu, L.F., Tainer, J.A., Trowbridge, I.S.

“…The internalization signals of several constitutively recycling receptors have recently been identified as regions of four or six amino acids that include an…”
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Rational design and expression of a heparin-targeted human superoxide dismutase by Boissinot, M, Kuhn, L A, Lee, P, Fisher, C L, Wang, Y, Hallewell, R A, Tainer, J A

“…In order to improve the therapeutic effectiveness of human Cu,Zn superoxide dismutase (HSOD) by targeting it to cell surfaces and increasing its circulatory…”
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Knowledge discovery in biological data sets using a hybrid Bayes classifier/evolutionary algorithm by Raymer, M.L., Kuhn, L.A., Punch, W.F.

“…A key element of bioinformatics research is the extraction of meaningful information from large experimental data sets. Various approaches, including…”
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