Search Results - "Kuhn, Brooks"

Improving Wildfire Readiness Among Patients With Chronic Obstructive Pulmonary Disease and Asthma: Applying a Population Health Approach to Climate Change by Kuhn, Brooks T, Gupta, Reshma

“…As a result of climate change, wildfire frequency, duration, and severity are increasing in the United States. Exposure to wildfire-related air pollutants can…”
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Work of Breathing During Proportional Assist Ventilation as a Predictor of Extubation Failure by Fazio, Sarina A, Lin, Gary, Cortés-Puch, Irene, Stocking, Jacqueline C, Tokeshi, Bradley, Kuhn, Brooks T, Adams, Jason Y, Harper, Richart

“…Despite decades of research on predictors of extubation success, use of ventilatory support after extubation is common and 10-20% of patients require…”
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How much do hospitalized adults move? A systematic review and meta-analysis by Fazio, Sarina, Stocking, Jacqueline, Kuhn, Brooks, Doroy, Amy, Blackmon, Emma, Young, Heather M., Adams, Jason Y.

“…To quantify the type and duration of physical activity performed by hospitalized adults. Inactivity is pervasive among hospitalized patients and is associated…”
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Editorial: Understanding the impact of lung ventilation heterogeneity by Kuhn, Brooks, Barjaktarevic, Igor

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Remote patient monitoring in the management of chronic obstructive pulmonary disease by Chalupsky, Megan R, Craddock, Krystal M, Schivo, Michael, Kuhn, Brooks T

“…Remote patient monitoring allows monitoring high-risk patients through implementation of an expanding number of technologies in coordination with a healthcare…”
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Alpha-1 antitrypsin deficiency and recombinant protein sources with focus on plant sources: Updates, challenges and perspectives by McNulty, Matthew J., Silberstein, David Z., Kuhn, Brooks T., Padgett, Hal S., Nandi, Somen, McDonald, Karen A., Cross, Carroll E.

“…Alpha-1 antitrypsin deficiency (A1ATD) is an autosomal recessive disease characterized by low plasma levels of A1AT, a serine protease inhibitor representing…”
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Leveraging IoTs and Machine Learning for Patient Diagnosis and Ventilation Management in the Intensive Care Unit by Rehm, Gregory B., Woo, Sang Hoon, Chen, Xin Luigi, Kuhn, Brooks T., Cortes-Puch, Irene, Anderson, Nicholas R., Adams, Jason Y., Chuah, Chen-Nee

“…Future healthcare systems will rely heavily on clinical decision support systems (CDSS) to improve the decision-making processes of clinicians. To explore the…”
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Viruses and non-allergen environmental triggers in asthma by Chau-Etchepare, Florence, Hoerger, Joshua L, Kuhn, Brooks T, Zeki, Amir A, Haczku, Angela, Louie, Samuel, Kenyon, Nicholas J, Davis, Cristina E, Schivo, Michael

“…Asthma is a complex inflammatory disease with many triggers. The best understood asthma inflammatory pathways involve signals characterized by peripheral…”
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A 51-Year-Old Man With Unresolved Pulmonary Infiltrates Following Streptococcus pneumoniae Pneumonia by Pugashetti, Janelle Vu, Adams, Jason Y., Zeki, Amir A., Kuhn, Brooks T.

“…A 51-year-old man presented to the clinic 8 weeks after a 6-day hospital admission for severe multilobar pneumonia caused by Streptococcus pneumoniae. His…”
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Development and Validation of a Multi-Algorithm Analytic Platform to Detect Off-Target Mechanical Ventilation by Adams, Jason Y., Lieng, Monica K., Kuhn, Brooks T., Rehm, Greg B., Guo, Edward C., Taylor, Sandra L., Delplanque, Jean-Pierre, Anderson, Nicholas R.

“…Healthcare-specific analytic software is needed to process the large volumes of streaming physiologic waveform data increasingly available from life support…”
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Development of a research-oriented system for collecting mechanical ventilator waveform data by Rehm, Gregory B, Kuhn, Brooks T, Delplanque, Jean-Pierre, Guo, Edward C, Lieng, Monica K, Nguyen, Jimmy, Anderson, Nicholas R, Adams, Jason Y

“…Abstract Lack of access to high-frequency, high-volume patient-derived data, such as mechanical ventilator waveform data, has limited the secondary use of…”
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Comparative Effectiveness of Roflumilast and Azithromycin for the Treatment of Chronic Obstructive Pulmonary Disease by Lam, Jenny, Tonnu-Mihara, Ivy, Kenyon, Nicholas J, Kuhn, Brooks T

“…In chronic obstructive pulmonary disease (COPD) patients with exacerbations despite optimized bronchodilator therapy, roflumilast and chronic azithromycin are…”
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A 56-Year-Old Male With Weight Loss, Night Sweats, Dyspnea, and Bladder Cancer by Sanville, Bradley C., Kuhn, Brooks T.

“…A 56-year-old man presented with subacute night sweats, fever, and weight loss with worsening dyspnea. Computed tomography (CT) scan demonstrated miliary…”
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Management of Mechanical Ventilation in Decompensated Heart Failure by Kuhn, Brooks T, Bradley, Laura A, Dempsey, Timothy M, Puro, Alana C, Adams, Jason Y

“…Mechanical ventilation (MV) is a life-saving intervention for respiratory failure, including decompensated congestive heart failure. MV can reduce ventricular…”
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A 66-Year-Old Man With Subacute Cough and Worsening Dyspnea Previously Diagnosed With COVID-19 Pneumonia by Quan, Michelle A., Hoerger, Joshua L., Mullins, Elizabeth H., Kuhn, Brooks T.

“…A 66-year-old man presented with subacute cough and worsening dyspnea. Labs were notable for moderate peripheral eosinophilia, and computed tomography (CT)…”
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Paradigms in chronic obstructive pulmonary disease: phenotypes, immunobiology, and therapy with a focus on vascular disease by Schivo, Michael, Albertson, Timothy E, Haczku, Angela, Kenyon, Nicholas J, Zeki, Amir A, Kuhn, Brooks T, Louie, Samuel, Avdalovic, Mark V

“…Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous syndrome that represents a major global health burden. COPD phenotypes have…”
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Recombinant Alpha-1 Antitrypsin-Fc Fusion Protein INBRX-101 in Adults With Alpha-1 Antitrypsin Deficiency: A Phase 1 Study by Brantly, Mark L, Kuhn, Brooks T, Farah, Humam W, Mahadeva, Ravi, Cole, Alexandra, Chang, Catherina L, Brown, Cynthia D, Campos, Michael A, Lascano, Jorge E, Babcock, Erin K, Bhagwat, Sharvari P, Boyea, Teresa F, Veldstra, Carson A, Andrianov, Vasily, Kalabus, James L, Eckelman, Brendan P, Veale, Andrew G

“…Alpha-1 antitrypsin deficiency (AATD) is characterized by low alpha-1 antitrypsin (AAT) levels, predisposing individuals to lung disease. The standard of care,…”
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Balloon dilation atrial septostomy for advanced pulmonary hypertension in patients on prostanoid therapy by Kuhn, Brooks T., Javed, Usman, Armstrong, Ehrin J., Singh, Gagan D., Smith, Thomas W., Whitcomb, Charles J., Allen, Roblee P., Rogers, Jason H.

“…Background: Prostanoid therapy improves quality of life and may increase survival in patients with advanced pulmonary hypertension (PH). Balloon dilated atrial…”
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An Unusual Case of Tertiary Syphilis Behaving Like Tongue Squamous Cell Carcinoma by Solis, Roberto N., Kuhn, Brooks T., Farwell, D. Gregory

“…Syphilis may present with a myriad of oral manifestations in the primary, secondary, and tertiary stages, and may be confused with malignancy. Despite a rise…”
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Use of Machine Learning to Screen for Acute Respiratory Distress Syndrome Using Raw Ventilator Waveform Data by Rehm, Gregory B, Cortés-Puch, Irene, Kuhn, Brooks T, Nguyen, Jimmy, Fazio, Sarina A, Johnson, Michael A, Anderson, Nicholas R, Chuah, Chen-Nee, Adams, Jason Y

“…To develop and characterize a machine learning algorithm to discriminate acute respiratory distress syndrome from other causes of respiratory failure using…”
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