Search Results - "Kuhn, Andreas"

Immigration, Cultural Distance and Natives' Attitudes Towards Immigrants: Evidence from Swiss Voting Results by Brunner, Beatrice, Kuhn, Andreas

“…Summary We combine community‐level outcomes of 27 votes about immigration issues in Switzerland with census data to estimate the effect of immigration on…”
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Membrane protein insertase YidC in bacteria and archaea by Kuhn, Andreas, Kiefer, Dorothee

“…Summary The insertion of proteins into the prokaryotic plasma membrane is catalyzed by translocases and insertases. On one hand, the Sec translocase operates…”
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Improving mRNA-Based Therapeutic Gene Delivery by Expression-Augmenting 3′ UTRs Identified by Cellular Library Screening by Orlandini von Niessen, Alexandra G., Poleganov, Marco A., Rechner, Corina, Plaschke, Arianne, Kranz, Lena M., Fesser, Stephanie, Diken, Mustafa, Löwer, Martin, Vallazza, Britta, Beissert, Tim, Bukur, Valesca, Kuhn, Andreas N., Türeci, Özlem, Sahin, Ugur

“…Synthetic mRNA has emerged as a powerful tool for the transfer of genetic information, and it is being explored for a variety of therapeutic applications. Many…”
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An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma by Sahin, Ugur, Oehm, Petra, Derhovanessian, Evelyna, Jabulowsky, Robert A., Vormehr, Mathias, Gold, Maike, Maurus, Daniel, Schwarck-Kokarakis, Doreen, Kuhn, Andreas N., Omokoko, Tana, Kranz, Lena M., Diken, Mustafa, Kreiter, Sebastian, Haas, Heinrich, Attig, Sebastian, Rae, Richard, Cuk, Katarina, Kemmer-Brück, Alexandra, Breitkreuz, Andrea, Tolliver, Claudia, Caspar, Janina, Quinkhardt, Juliane, Hebich, Lisa, Stein, Malte, Hohberger, Alexander, Vogler, Isabel, Liebig, Inga, Renken, Stephanie, Sikorski, Julian, Leierer, Melanie, Müller, Verena, Mitzel-Rink, Heidrun, Miederer, Matthias, Huber, Christoph, Grabbe, Stephan, Utikal, Jochen, Pinter, Andreas, Kaufmann, Roland, Hassel, Jessica C., Loquai, Carmen, Türeci, Özlem

“…Treating patients who have cancer with vaccines that stimulate a targeted immune response is conceptually appealing, but cancer vaccine trials have not been…”
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Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy by Kranz, Lena M., Diken, Mustafa, Haas, Heinrich, Kreiter, Sebastian, Loquai, Carmen, Reuter, Kerstin C., Meng, Martin, Fritz, Daniel, Vascotto, Fulvia, Hefesha, Hossam, Grunwitz, Christian, Vormehr, Mathias, Hüsemann, Yves, Selmi, Abderraouf, Kuhn, Andreas N., Buck, Janina, Derhovanessian, Evelyna, Rae, Richard, Attig, Sebastian, Diekmann, Jan, Jabulowsky, Robert A., Heesch, Sandra, Hassel, Jessica, Langguth, Peter, Grabbe, Stephan, Huber, Christoph, Türeci, Özlem, Sahin, Ugur

“…The development of a nanoparticle RNA vaccine is reported that preferentially targets dendritic cells after systemic administration, and is shown to provide…”
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Parallelized Acquisition of Orbitrap and Astral Analyzers Enables High-Throughput Quantitative Analysis by Stewart, Hamish I., Grinfeld, Dmitry, Giannakopulos, Anastassios, Petzoldt, Johannes, Shanley, Toby, Garland, Matthew, Denisov, Eduard, Peterson, Amelia C., Damoc, Eugen, Zeller, Martin, Arrey, Tabiwang N., Pashkova, Anna, Renuse, Santosh, Hakimi, Amirmansoor, Kühn, Andreas, Biel, Matthias, Kreutzmann, Arne, Hagedorn, Bernd, Colonius, Immo, Schütz, Adrian, Stefes, Arne, Dwivedi, Ankit, Mourad, Daniel, Hoek, Max, Reitemeier, Bastian, Cochems, Philipp, Kholomeev, Alexander, Ostermann, Robert, Quiring, Gregor, Ochmann, Maximilian, Möhring, Sascha, Wagner, Alexander, Petker, André, Kanngiesser, Sebastian, Wiedemeyer, Michael, Balschun, Wilko, Hermanson, Daniel, Zabrouskov, Vlad, Makarov, Alexander A., Hock, Christian

“…The growing trend toward high-throughput proteomics demands rapid liquid chromatography–mass spectrometry (LC–MS) cycles that limit the available time to…”
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Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer by Sahin, Ugur, Derhovanessian, Evelyna, Miller, Matthias, Kloke, Björn-Philipp, Simon, Petra, Löwer, Martin, Bukur, Valesca, Tadmor, Arbel D., Luxemburger, Ulrich, Schrörs, Barbara, Omokoko, Tana, Vormehr, Mathias, Albrecht, Christian, Paruzynski, Anna, Kuhn, Andreas N., Buck, Janina, Heesch, Sandra, Schreeb, Katharina H., Müller, Felicitas, Ortseifer, Inga, Vogler, Isabel, Godehardt, Eva, Attig, Sebastian, Rae, Richard, Breitkreuz, Andrea, Tolliver, Claudia, Suchan, Martin, Martic, Goran, Hohberger, Alexander, Sorn, Patrick, Diekmann, Jan, Ciesla, Janko, Waksmann, Olga, Brück, Alexandra-Kemmer, Witt, Meike, Zillgen, Martina, Rothermel, Andree, Kasemann, Barbara, Langer, David, Bolte, Stefanie, Diken, Mustafa, Kreiter, Sebastian, Nemecek, Romina, Gebhardt, Christoffer, Grabbe, Stephan, Höller, Christoph, Utikal, Jochen, Huber, Christoph, Loquai, Carmen, Türeci, Özlem

“…The authors report the first-in-human application of personalized neo-antigen RNA vaccines in patients with melanoma. Personalized cancer vaccine trials…”
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Exploiting the Mutanome for Tumor Vaccination by CASTLE, John C, KREITER, Sebastian, KOSLOWSKI, Michael, KUHN, Andreas N, BRITTEN, Cedrik M, HUBER, Christoph, TÜRECI, Ozlem, SAHIN, Ugur, DIEKMANN, Jan, LÖWER, Martin, DE ROEMER, Niels Van, DE GRAAF, Jos, SELMI, Abderraouf, DIKEN, Mustafa, BOEGEL, Sebastian, PARET, Claudia

“…Multiple genetic events and subsequent clonal evolution drive carcinogenesis, making disease elimination with single-targeted drugs difficult. The multiplicity…”
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BNT162b vaccines protect rhesus macaques from SARS-CoV-2 by Vogel, Annette B., Kanevsky, Isis, Che, Ye, Swanson, Kena A., Muik, Alexander, Vormehr, Mathias, Kranz, Lena M., Walzer, Kerstin C., Hein, Stephanie, Güler, Alptekin, Loschko, Jakob, Maddur, Mohan S., Ota-Setlik, Ayuko, Tompkins, Kristin, Cole, Journey, Lui, Bonny G., Ziegenhals, Thomas, Plaschke, Arianne, Eisel, David, Dany, Sarah C., Fesser, Stephanie, Erbar, Stephanie, Bates, Ferdia, Schneider, Diana, Jesionek, Bernadette, Sänger, Bianca, Wallisch, Ann-Kathrin, Feuchter, Yvonne, Junginger, Hanna, Krumm, Stefanie A., Heinen, André P., Adams-Quack, Petra, Schlereth, Julia, Schille, Stefan, Kröner, Christoph, de la Caridad Güimil Garcia, Ramón, Hiller, Thomas, Fischer, Leyla, Sellers, Rani S., Choudhary, Shambhunath, Gonzalez, Olga, Vascotto, Fulvia, Gutman, Matthew R., Fontenot, Jane A., Hall-Ursone, Shannan, Brasky, Kathleen, Griffor, Matthew C., Han, Seungil, Su, Andreas A. H., Lees, Joshua A., Nedoma, Nicole L., Mashalidis, Ellene H., Sahasrabudhe, Parag V., Tan, Charles Y., Pavliakova, Danka, Singh, Guy, Fontes-Garfias, Camila, Pride, Michael, Scully, Ingrid L., Ciolino, Tara, Obregon, Jennifer, Gazi, Michal, Carrion, Ricardo, Alfson, Kendra J., Kalina, Warren V., Kaushal, Deepak, Shi, Pei-Yong, Klamp, Thorsten, Rosenbaum, Corinna, Kuhn, Andreas N., Türeci, Özlem, Dormitzer, Philip R., Jansen, Kathrin U., Sahin, Ugur

“…A safe and effective vaccine against COVID-19 is urgently needed in quantities that are sufficient to immunize large populations. Here we report the…”
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The impact of labor market entry conditions on initial job assignment and wages by Brunner, Beatrice, Kuhn, Andreas

“…We estimate the effects of labor market entry conditions on wages for male individuals first entering the Austrian labor market between 1978 and 2000. We find…”
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Membrane Insertion of the M13 Minor Coat Protein G3p Is Dependent on YidC and the SecAYEG Translocase by Kleinbeck, Farina, Kuhn, Andreas

“…The minor coat protein G3p of bacteriophage M13 is the key component for the host interaction of this virus and binds to Escherichia coli at the tip of the F…”
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Involvement of the Cell Division Protein DamX in the Infection Process of Bacteriophage T4 by Wenzel, Sabrina, Hess, Renate, Kiefer, Dorothee, Kuhn, Andreas

“…The molecular mechanism of how the infecting DNA of bacteriophage T4 passes from the capsid through the bacterial cell wall and enters the cytoplasm is…”
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Cap analogs modified with 1,2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential by Strenkowska, Malwina, Grzela, Renata, Majewski, Maciej, Wnek, Katarzyna, Kowalska, Joanna, Lukaszewicz, Maciej, Zuberek, Joanna, Darzynkiewicz, Edward, Kuhn, Andreas N, Sahin, Ugur, Jemielity, Jacek

“…Along with a growing interest in mRNA-based gene therapies, efforts are increasingly focused on reaching the full translational potential of mRNA, as a major…”
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The MAIN Shirt: a textile-integrated magnetic induction sensor array by Teichmann, Daniel, Kuhn, Andreas, Leonhardt, Steffen, Walter, Marian

“…A system is presented for long-term monitoring of respiration and pulse. It comprises four non-contact sensors based on magnetic eddy current induction that…”
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Cone versus conventional repair for Ebstein's anomaly by Burri, Melchior, Mrad Agua, Karim, Cleuziou, Julie, Beran, Elisabeth, Nagdyman, Nicole, Kühn, Andreas, Ziegelmueller, Johannes Amadeus, Ewert, Peter, Da Silva, Jose Pedro, Lange, Rüdiger

“…We aimed to investigate tricuspid valve function and adverse events after conventional repair and valve replacement for Ebstein's anomaly and compare them with…”
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Dynamic Disulfide Scanning of the Membrane-inserting Pf3 Coat Protein Reveals Multiple YidC Substrate Contacts by Klenner, Christian, Kuhn, Andreas

“…The membrane insertase YidC inserts newly synthesized proteins into the plasma membrane. While defects in YidC homologs in animals and plants cause diseases,…”
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Detection, production, and application of microbial arylsulfatases by Stressler, Timo, Seitl, Ines, Kuhn, Andreas, Fischer, Lutz

“…Arylsulfatases are enzymes which catalyze the hydrolysis of arylsulfate ester bonds to release a free sulfonate. They are widespread in nature and are found in…”
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Characterization of BNT162b2 mRNA to Evaluate Risk of Off-Target Antigen Translation by Patel, Himakshi K, Zhang, Kun, Utegg, Rachael, Stephens, Elaine, Salem, Shauna, Welch, Heidi, Grobe, Svenja, Schlereth, Julia, Kuhn, Andreas N, Ryczek, Jeff, Cirelli, David J, Lerch, Thomas F

“…mRNA vaccines have been established as a safe and effective modality, thanks in large part to the expedited development and approval of COVID-19 vaccines. In…”
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The Beauty of Bacteriophage T4 Research: Lindsay W. Black and the T4 Head Assembly by Kuhn, Andreas, Thomas, Julie A

“…Viruses are biochemically complex structures and mainly consist of folded proteins that contain nucleic acids. Bacteriophage T4 is one of most prominent…”
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Assembly of Bacterial Inner Membrane Proteins by Dalbey, Ross E, Wang, Peng, Kuhn, Andreas

“…Numerous membrane proteins form multisubunit protein complexes, which contain both integral and peripheral subunits, in addition to prosthetic groups…”
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