Search Results - "Kuhar, M. J"

CART peptides: regulators of body weight, reward and other functions by Kuhar, M. J, Rogge, G, Jones, D, Hubert, G. W, Lin, Y

“…Key Points The CART (cocaine- and amphetamine-regulated transcript) gene, transcripts and peptides were discovered through the initial observation that…”
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Maternal separation alters drug intake patterns in adulthood in rats by Moffett, M.C., Vicentic, A., Kozel, Marie, Plotsky, Paul, Francis, D.D., Kuhar, M.J.

“…Maternal separation/handling (MS/H) is an animal model of early life stress that causes profound neurochemical and behavioral alterations in pups that persist…”
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Frequency of maternal licking and grooming correlates negatively with vulnerability to cocaine and alcohol use in rats by Francis, D.D., Kuhar, M.J.

“…Because licking and grooming behavior of dams with pups can influence some behaviors of pups when they are adults, we tested if licking and grooming scores in…”
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Intra-accumbal administration of shRNAs against CART peptides cause increases in body weight and cocaine-induced locomotor activity in rats by Job, M.O, Licata, J, Hubert, G.W, Kuhar, M.J

“…Abstract In order to examine the effect of cocaine and amphetamine regulated transcript (CART) peptide depletion in adult rats, CART shRNAs or scrambled…”
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Maternal separation alters serotonergic transporter densities and serotonergic 1A receptors in rat brain by Vicentic, A., Francis, D., Moffett, M., Lakatos, A., Rogge, G., Hubert, G.W., Harley, J., Kuhar, M.J.

“…The basic mechanisms underlying the association between early life maternal separation and adulthood psychiatric disorders are largely unknown. One possible…”
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Cocaine and amphetamine-regulated transcript-containing neurons in the nucleus accumbens project to the ventral pallidum in the rat and may inhibit cocaine-induced locomotion by Hubert, G.W, Manvich, D.F, Kuhar, M.J

“…Abstract We have previously demonstrated that cocaine- and amphetamine-regulated transcript (CART) peptide colocalizes with GABA, dynorphin, D1 receptors, and…”
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Effects of early maternal separation on ethanol intake, GABA receptors and metabolizing enzymes in adult rats by JAWORSKI, J. N, FRANCIS, D. D, BROMMER, C. L, MORGAN, E. T, KUHAR, M. J

“…Maternal separation (MS) in neonatal rats affects ethanol self-administration (SA) in adulthood; however, the conditions and mechanisms need to be clarified…”
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CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight by Wierup, N., Richards, W.G., Bannon, A.W., Kuhar, M.J., Ahrén, B., Sundler, F.

“…CART peptides are anorexigenic and are widely expressed in the central and peripheral nervous systems, as well as in endocrine cells in the pituitary, adrenal…”
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Understanding the Global Problem of Drug Addiction is a Challenge for IDARS Scientists by Ali, S F, Onaivi, E S, Dodd, P R, Cadet, J L, Schenk, S, Kuhar, M J, Koob, G F

“…IDARS is an acronym for the International Drug Abuse Research Society. Apart from our scientific and educational purposes, we communicate information to the…”
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Cocaine- and Amphetamine-Regulated Transcript Peptide Levels in Blood Exhibit a Diurnal Rhythm: Regulation by Glucocorticoids by Vicentic, A, Dominguez, G, Hunter, R. G, Philpot, K, Wilson, M, Kuhar, M. J

“…Cocaine- and amphetamine-regulated transcript (CART) peptides are novel neurotransmitters that are implicated in several physiological functions such as…”
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Adolescents carrying a missense mutation in the CART gene exhibit increased anxiety and depression by Miraglia del Giudice, E., Santoro, N., Fiumani, P., Dominguez, G., Kuhar, M. J., Perrone, L.

“…A Leu34Phe mutation in the cocaine‐ and amphetamine‐regulated transcript (CART) gene has been associated with severe early‐onset obesity in an affected family…”
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CART peptides: regulators of body weight, reward and other functions by Rogge, G, Jones, D, Hubert, G. W, Lin, Y, Kuhar, M. J

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Cocaine administration increases the fraction of CART cells in the rat nucleus accumbens that co-immunostain for c-Fos by Hubert, G.W, Kuhar, M.J

“…Abstract In order to further test whether or not psychostimulant drugs activate CART peptide-containing cells in the nucleus accumbens, we examined the…”
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Pharmacotherapies for Treatment of Cocaine Abuse:  Preclinical Aspects by Carroll, F. Ivy, Howell, Leonard L, Kuhar, Michael J

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Neurotransmitter transporters : recent progress by AMARA, S. G, KUHAR, M. J

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CART peptides by Kuhar, M.J., Adams, S., Dominguez, G., Jaworski, J., Balkan, B.

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CART Peptides Regulate Psychostimulants and May be Endogenous Antidepressants by Job, M O, McNamara, I M, Kuhar, M J

“…CART peptides are endogenous neurotransmitters that are involved in a variety of physiologic functions. Injection of CART 55-102 into the nucleus accumbens…”
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Unique responses of midbrain CART neurons in macaques to ovarian steroids by Lima, F.B, Henderson, J.A, Reddy, A.P, Tokuyama, Y, Hubert, G.W, Kuhar, M.J, Bethea, C.L

“…Abstract CART (cocaine and amphetamine regulated transcript) is a neuropeptide involved in the control of several physiological processes, such as response to…”
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CART peptides: novel addiction- and feeding-related neuropeptides by Kuhar, Michael J., Dall Vechia, Stephanie E.

“…CART peptides are novel, putative brain–gut neurotransmitters and co-transmitters that probably have a role in drug abuse, the control of feeding behavior,…”
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A cocaine-and-amphetamine-regulated-transcript peptide projection from the lateral hypothalamus to the ventral tegmental area by Philpot, K.B., Dallvechia-Adams, S., Smith, Y., Kuhar, M.J.

“…Cocaine-and-amphetamine-regulated-transcript peptides play a role in the modulation of feeding and psychomotor stimulant-like behaviors. The ventral tegmental…”
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