Search Results - "Kugler, Z."

SMAP Passive Microwave Radiometer for Global River Flow Monitoring by Kugler, Z., Nghiem, S. V., Brakenridge, G. R.

“…River flow is a fundamental observable in hydrology, but there is no consistent global ground measurement network. Various types of orbital remote sensing are,…”
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Ice Freeze‐Up and Break‐Up in Arctic Rivers Observed With Satellite L‐Band Passive Microwave Data From 2010 to 2020 by Podkowa, A., Kugler, Z., Nghiem, S. V., Brakenridge, G. R.

“…The timing of ice freeze‐up and break‐up in the Arctic may be responding to climate change. Passive microwave remote sensing is a powerful technique for…”
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Identification of pharmacological inhibitors of the MEK5/ERK5 pathway by Tatake, Revati J., O’Neill, Margaret M., Kennedy, Charles A., Wayne, Anita L., Jakes, Scott, Wu, Di, Kugler, Stanley Z., Kashem, Mohammed A., Kaplita, Paul, Snow, Roger J.

“…We have identified two novel MEK5 inhibitors, BIX02188 and BIX02189, which inhibited catalytic function of purified, MEK5 enzyme. The MEK5 inhibitors blocked…”
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IMPROVING DATA QUALITY AND MANAGEMENT FOR REMOTE SENSING ANALYSIS: USE-CASES AND EMERGING RESEARCH QUESTIONS by Breunig, M., Kuper, P., Reitze, F., Landgraf, S., Al-Doori, M., Stefanakis, E., Abdulmuttalib, H., Kugler, Z.

“…During the last decades satellite remote sensing has become an emerging technology producing big data for various application fields every day. However, data…”
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TIME-RELATED QUALITY DIMENSIONS OF URBAN REMOTELY SENSED BIG DATA by Kugler, Z., Szabó, G., Abdulmuttalib, H. M., Batini, C., Shen, H., Barsi, A., Huang, G.

“…Our rapidly changing world requires new sources of image based information. The quickly changing urban areas, the maintenance and management of smart cities…”
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Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug design by Cook, Brian N., Bentzien, Jörg, White, Andre, Nemoto, Peter A., Wang, Ji, Man, Chuk C., Soleymanzadeh, Fariba, Khine, Hnin Hnin, Kashem, Mohammed A., Kugler, Stanley Z., Wolak, John P., Roth, Gregory P., De Lombaert, Stéphane, Pullen, Steven S., Takahashi, Hidenori

“…This work describes the discovery of ITK inhibitors through structure-based design where high-resolution crystal structural information was used to optimize…”
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5-Aminomethylbenzimidazoles as potent ITK antagonists by RIETHER, Doris, ZINDELL, Renée, RAYMOND, Ernest L, KHINE, Hnin Hnin, O'SHEA, Kathy, WOSKA, Joseph R, JEANFAVRE, Deborah, SELLATI, Rosemarie, RALPH, Kerry L. M, AHLBERG, Jennifer, LABISSIERE, Gabriel, KASHEM, Mohammed A, KOWALSKI, Jennifer A, PULLEN, Steven S, TAKAHASHI, Hidenori, COOK, Brian N, BENTZIEN, Jörg, DE LOMBAERT, Stéphane, THOMSON, David, KUGLER, Stanley Z, SKOW, Donna, MARTIN, Leslie S

“…Benzamide 1 demonstrated good potency as a selective ITK inhibitor, however the amide moiety was found to be hydrolytically labile in vivo, resulting in low…”
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Mitigation of off-target adrenergic binding and effects on cardiovascular function in the discovery of novel ribosomal S6 kinase 2 inhibitors by Fryer, Ryan M, Muthukumarana, Akalushi, Chen, Rong Rhonda, Smith, James D, Mazurek, Suzanne Nodop, Harrington, Kyle E, Dinallo, Roger M, Burke, Jennifer, DiCapua, Frank M, Guo, Xin, Kirrane, Thomas M, Snow, Roger J, Zhang, Yunlong, Soleymanzadeh, Fariba, Madwed, Jeffrey B, Kashem, Mohammed A, Kugler, Stanley Z, O'Neill, Margaret M, Harrison, Paul C, Reinhart, Glenn A, Boyer, Stephen J

“…We previously reported the discovery of a novel ribosomal S6 kinase 2 (RSK2) inhibitor, (R)-5-Methyl-1-oxo-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,2-a]…”
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2-Aminobenzimidazoles as potent ITK antagonists: trans-stilbene-like moieties targeting the kinase specificity pocket by Lo, Ho Yin, Bentzien, Jörg, Fleck, Roman W, Pullen, Steven S, Khine, Hnin Hnin, Woska, Jr, Joseph R, Kugler, Stanley Z, Kashem, Mohammed A, Takahashi, Hidenori

“…Based on the information from molecular modeling and X-ray crystal structures, the kinase specificity pocket of ITK could be occupied upon extension of the…”
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Remote Sensing Data Quality in the Era of AI by Abdulmuttalib, Hussein, Al Doori, Mulhim, Barsi, Árpád, Blaschke, Thomas, Gao, Yunya, Kugler, Zsofia, Lang, Stefan, Szabo, Gyorgy, Tiede, Dirk

“…The era of Artificial Intelligence ‘AI’ with all the benefits brought along, has raised new and additional challenges to the ongoing efforts of assessing,…”
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Preoperative examination of inflammatory biomarkers in relation to the prognosis of postoperative complications after heart transplantation by Tarjanyi, Z, Bernath, D, Szappanos, A, Teszak, T, Kiraly, A, Kugler, S Z, Pallinger, E, Nagy, G Y, Sax, B, Merkely, B

“…Abstract Funding Acknowledgements  Type of funding sources: Public hospital(s). Main funding source(s): Semmelweis University Heart transplantation (HTX) is…”
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X-ray absorption and magnetic circular dichroism studies of Co2FeAl in magnetic tunnel junctions by Ebke, D., Kugler, Z., Thomas, P., Schebaum, O., Schafers, M., Nissen, D., Schmalhorst, J., Hutten, A., Arenholz, E., Thomas, A.

“…The bulk magnetic moment and the element specific magnetic moment of Co{sub 2}FeAl thin films were examined as a function of annealing temperature by…”
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Fibrinopeptide-A as thrombotic risk marker in diabetic and atherosclerotic coronary vasculopathy by Horváth, M, Pszota, A, Rahói, K, Kugler, Z, Evel, S, Szigeti, G

“…Fibrinopeptide A was determined in 75 middle aged male patients, five control subjects and a control group of young medical students, divided into nine…”
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P294Predictors of long-term mortality and re-ablation in patients undergoing ischaemic or non-ischaemic VT ablation by Nagy, K V, Szegedi, N, Szabo-Madacsi, E, Kugler, S Z, Herczeg, S Z, Sallo, Z, Szeplaki, G, Tahin, T, Osztheimer, I, Merkely, B, Geller, L

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P299Clinical and echocardiographic parameters predicting long-term mortality in patients undergoing ischaemic or non-ischaemic VT ablation by Nagy, K V, Szegedi, N, Kugler, S Z, Sallo, Z, Osztheimer, I, Herczeg, S Z, Szeplaki, G, Tahin, T, Merkely, B, Geller, L

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Perinatal and intrafamily transmission of hepatitis B virus in three generations of a low-prevalence population by Ördög, Katalin, Szendrôi, Andrea, Szarka, Katalin, Kugler, Zoltán, Csire, Márta, Kapusinszky, Beatrix, Xie, Jiuru, Csizmadia, Katalin, Brojnás, Judit, Rusvai, Erzsébet, Tempfli, Ágnes, Berencsi, György

“…Family members of 47 hepatitis B virus (HBV)‐carrier pregnant women were tested for the presence of hepatitis B surface antigen (HBsAg), other markers of HBV…”
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2-Aminobenzimidazoles as potent 1TK antagonists : trans-stilbene-like moieties targeting the kinase specificity pocket by HO YIN LO, BENTZIEN, Jörg, FLECK, Roman W, PULLEN, Steven S, HNIN HNIN KHINE, WOSKA, Joseph R, KUGLER, Stanley Z, KASHEM, Mohammed A, TAKAHASHI, Hidenori

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