Search Results - "Kugaevskaia, E V"
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Membrane type 1 matrix metalloproteinase (MT1-MMP) and the regulators of its activity as invasive factors in squamous cell cervical carcinomas
Published in Biomeditsinskaia khimiia (01-11-2014)“…Membrane type 1 matrix metalloproteinase (MT1MMP) is one of matrix metalloproteinases (MMP), which play а key role in tumor invasion and metastasis. The aim of…”
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Angiotensin converting enzyme and Alzheimer's disease
Published in Biomeditsinskaia khimiia (01-01-2013)“…Alzheimer's disease (AD) is an incurable degenerative disease of the central nervous system, leading to dementia. The basis of AD is neurodegenerative process…”
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Key enzymes of degradation and angiogenesis as a factors of tumor progression in squamous cell carcinoma of the cervix
Published in Bioorganicheskaia khimiia (01-11-2014)“…A key role in tumor progression play two processes--the destruction and angiogenesis. Matrix metalloproteases (MMPs) play a leading role during tissue…”
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ACE inhibitors--activators of kinin receptors
Published in Biomeditsinskaia khimiia (01-05-2011)“…Angiotensin converting enzyme (ACE) inhibitors are widely used for treatment of cardiovascular diseases. The effects of ACE inhibitors on the human bradykinin…”
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Structure and physiological significance of angiotensin converting enzyme domains
Published in Biomeditsinskaia khimiia (01-07-2009)“…Somatic angiotensin converting enzyme (ACE) consists of two homologous catalytic domains (N- and C-domain), each of which bears an active site exhibiting…”
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Angiotensin converting enzyme domain structure and properties
Published in Biomeditsinskaia khimiia (01-11-2005)“…Angiotensin converting enzyme (ACE) is a key enzyme of the renin-angiotensin and kallikrein-kinin systems responsible for the regulation of blood pressure…”
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Study of substrate specificity of a new peptide substrate of endothelin converting enzyme
Published in Biomeditsinskaia khimiia (01-03-2007)“…The new fluorogenic hexapeptide substrate CMC-Ala-Gly-Gly-Trp-Phe-Arg was used as substrate for endothelin-converting enzyme (ECE), angiotensin-converting…”
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Participation of serine proteinases in transforming the high molecular weight (600 kDa) form of angiotensin 1-converting enzyme into the low molecular weight form (190 kDa)
Published in Voprosy meditsinskoi khimii (01-05-1994)“…A high molecular form of angiotensin-converting enzyme with mol mass about 600 kDa was found simultaneously with the well-known low molecular enzyme form of…”
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Induction of blood plasma carboxycathepsin (angiotensin I-converting enzyme) in normo- and hypertensive rats in response to a single administration of captopril
Published in Biulleten' eksperimental'noi biologii i meditsiny (01-01-1987)“…The experiments were carried out to elucidate the effect of carboxycathepsin (CC) activity inhibition by a specific inhibitor--captopril--on plasma enzyme…”
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Inhibition of the angiotensin-converting enzyme from bovine kidney by organophosphorus analogs of amino acids
Published in Voprosy meditsinskoi khimii (01-07-1990)“…Reactions of amino acid phosphoorganic derivatives with angiotensin-converting enzyme (dipeptidyl carboxypeptidase) were studied. Substitution of the amino…”
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