Search Results - "Kuestner, Rolf"

Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival by Grosse-Wilde, Anne, Fouquier d'Hérouël, Aymeric, McIntosh, Ellie, Ertaylan, Gökhan, Skupin, Alexander, Kuestner, Rolf E, del Sol, Antonio, Walters, Kathie-Anne, Huang, Sui

“…Breast cancer stem cells (CSCs) are thought to drive recurrence and metastasis. Their identity has been linked to the epithelial to mesenchymal transition…”
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Development of spirulina for the manufacture and oral delivery of protein therapeutics by Jester, Benjamin W., Zhao, Hui, Gewe, Mesfin, Adame, Thomas, Perruzza, Lisa, Bolick, David T., Agosti, Jan, Khuong, Nhi, Kuestner, Rolf, Gamble, Caitlin, Cruickshank, Kendra, Ferrara, Jeremy, Lim, Rachelle, Paddock, Troy, Brady, Colin, Ertel, Stacey, Zhang, Miaohua, Pollock, Alex, Lee, Jamie, Xiong, Jian, Tasch, Michael, Saveria, Tracy, Doughty, David, Marshall, Jacob, Carrieri, Damian, Goetsch, Lauren, Dang, Jason, Sanjaya, Nathaniel, Fletcher, David, Martinez, Anissa, Kadis, Bryce, Sigmar, Kristjan, Afreen, Esha, Nguyen, Tammy, Randolph, Amanda, Taber, Alexandria, Krzeszowski, Ashley, Robinett, Brittney, Volkin, David B., Grassi, Fabio, Guerrant, Richard, Takeuchi, Ryo, Finrow, Brian, Behnke, Craig, Roberts, James

“…The use of the edible photosynthetic cyanobacterium Arthrospira platensis (spirulina) as a biomanufacturing platform has been limited by a lack of genetic…”
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Identification of the IL-17 Receptor Related Molecule IL-17RC as the Receptor for IL-17F by Kuestner, Rolf E, Taft, David W, Haran, Aaron, Brandt, Cameron S, Brender, Ty, Lum, Karen, Harder, Brandon, Okada, Shannon, Ostrander, Craig D, Kreindler, James L, Aujla, Shean J, Reardon, Brian, Moore, Margaret, Shea, Pamela, Schreckhise, Randall, Bukowski, Thomas R, Presnell, Scott, Guerra-Lewis, Patricia, Parrish-Novak, Julia, Ellsworth, Jeff L, Jaspers, Stephen, Lewis, Katherine E, Appleby, Mark, Kolls, Jay K, Rixon, Mark, West, James W, Gao, Zeren, Levin, Steven D

“…The proinflammatory cytokines IL-17A and IL-17F have a high degree of sequence similarity and share many biological properties. Both have been implicated as…”
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1918 pandemic influenza virus and Streptococcus pneumoniae co-infection results in activation of coagulation and widespread pulmonary thrombosis in mice and humans by Walters, Kathie-Anne, D'Agnillo, Felice, Sheng, Zong-Mei, Kindrachuk, Jason, Schwartzman, Louis M, Kuestner, Rolf E, Chertow, Daniel S, Golding, Basil T, Taubenberger, Jeffery K, Kash, John C

“…To study bacterial co‐infection following 1918 H1N1 influenza virus infection, mice were inoculated with the 1918 influenza virus, followed by Streptococcus…”
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Treatment with the reactive oxygen species scavenger EUK-207 reduces lung damage and increases survival during 1918 influenza virus infection in mice by Kash, John C., Xiao, Yongli, Davis, A.Sally, Walters, Kathie-Anne, Chertow, Daniel S., Easterbrook, Judith D., Dunfee, Rebecca L., Sandouk, Aline, Jagger, Brett W., Schwartzman, Louis M., Kuestner, Rolf E., Wehr, Nancy B., Huffman, Karl, Rosenthal, Rosalind A., Ozinsky, Adrian, Levine, Rodney L., Doctrow, Susan R., Taubenberger, Jeffery K.

“…The 1918 influenza pandemic caused over 40 million deaths worldwide, with 675,000 deaths in the United States alone. Studies in several experimental animal…”
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Francisella tularensis subsp. tularensis induces a unique pulmonary inflammatory response: role of bacterial gene expression in temporal regulation of host defense responses by Walters, Kathie-Anne, Olsufka, Rachael, Kuestner, Rolf E, Cho, Ji Hoon, Li, Hong, Zornetzer, Gregory A, Wang, Kai, Skerrett, Shawn J, Ozinsky, Adrian

“…Pulmonary exposure to Francisella tularensis is associated with severe lung pathology and a high mortality rate. The lack of induction of classical…”
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Prior infection with Type A Francisella tularensis antagonizes the pulmonary transcriptional response to an aerosolized Toll-like receptor 4 agonist by Walters, Kathie-Anne, Olsufka, Rachael, Kuestner, Rolf E, Wu, Xiagang, Wang, Kai, Skerrett, Shawn J, Ozinsky, Adrian

“…Francisella infection attenuates immune cell infiltration and expression of selected pro-inflammatory cytokines in response to endogenous LPS, suggesting the…”
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Lethal synergism of 2009 pandemic H1N1 influenza virus and Streptococcus pneumoniae coinfection is associated with loss of murine lung repair responses by Kash, John C, Walters, Kathie-Anne, Davis, A Sally, Sandouk, Aline, Schwartzman, Louis M, Jagger, Brett W, Chertow, Daniel S, Li, Qi, Kuestner, Rolf E, Ozinsky, Adrian, Taubenberger, Jeffery K

“…Secondary bacterial infections increase disease severity of influenza virus infections and contribute greatly to increased morbidity and mortality during…”
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Protocol for the transformation and engineering of edible algae Arthrospira platensis to generate heterologous protein-expressing strains by Tabakh, Hannah, Jester, Benjamin W., Zhao, Hui, Kuestner, Rolf, Khuong, Nhi, Shanitta, Chelsea, Takeuchi, Ryo, Roberts, James

“…Here, we present a protocol for harnessing the natural transformability of the edible algae Arthrospira platensis (common name: spirulina) to generate strains…”
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A Novel Mammalian Receptor for the Evolutionarily Conserved Type II GnRH by Millar, Robert, Lowe, Steven, Conklin, Darrell, Pawson, Adam, Maudsley, Stuart, Troskie, Brigitte, Ott, Thomas, Millar, Michael, Lincoln, Gerald, Sellar, Robin, Faurholm, Bjarne, Scobie, Graeme, Kuestner, Rolf, Terasawa, Ei, Katz, Arieh

“…Mammalian gonadotropin-releasing hormone (GnRH I: pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) stimulates pituitary gonadotropin secretion, which in turn…”
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SILAC Compatible Strain of Pichia pastoris for Expression of Isotopically Labeled Protein Standards and Quantitative Proteomics by Austin, Ryan J, Kuestner, Rolf E, Chang, Debbie K, Madden, Knut R, Martin, Daniel B

“…The methylotrophic yeast Pichia pastoris is a powerful eukaryotic platform for the production of heterologous protein. Recent publication of the P. pastoris…”
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Proteomic Analysis of Dhh1 Complexes Reveals a Role for Hsp40 Chaperone Ydj1 in Yeast P-Body Assembly by Cary, Gregory A, Vinh, Dani B N, May, Patrick, Kuestner, Rolf, Dudley, Aimée M

“…P-bodies (PB) are ribonucleoprotein (RNP) complexes that aggregate into cytoplasmic foci when cells are exposed to stress. Although the conserved mRNA decay…”
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Expression of IL-17B in neurons and evaluation of its possible role in the chromosome 5q-linked form of Charcot–Marie–Tooth disease by Moore, Emma E., Presnell, Scott, Garrigues, Ursula, Guilbot, Angele, LeGuern, Eric, Smith, Deborah, Yao, Lena, Whitmore, Theodore E., Gilbert, Teresa, Palmer, Theo D., Horner, Philip J., Kuestner, Rolf E.

“…IL-17B is a recently identified homolog of IL-17. Northern analysis revealed that IL-17B mRNA is expressed at very high levels in spinal cord and at much lower…”
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Chimeric Human Calcitonin and Glucagon Receptors Reveal Two Dissociable Calcitonin Interaction Sites by Stroop, Steven D, Kuestner, Rolf E, Serwold, Thomas F, Chen, Lennie, Moore, Emma E

“…Two chimeric receptors were constructed by transposing the coding regions for the putative N-terminal domains of the human calcitonin (hCTR) and glucagon…”
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Author Correction: Development of spirulina for the manufacture and oral delivery of protein therapeutics by Jester, Benjamin W., Zhao, Hui, Gewe, Mesfin, Adame, Thomas, Perruzza, Lisa, Bolick, David T., Agosti, Jan, Khuong, Nhi, Kuestner, Rolf, Gamble, Caitlin, Cruickshank, Kendra, Ferrara, Jeremy, Lim, Rachelle, Paddock, Troy, Brady, Colin, Ertel, Stacey, Zhang, Miaohua, Pollock, Alex, Lee, Jamie, Xiong, Jian, Tasch, Michael, Saveria, Tracy, Doughty, David, Marshall, Jacob, Carrieri, Damian, Goetsch, Lauren, Dang, Jason, Sanjaya, Nathaniel, Fletcher, David, Martinez, Anissa, Kadis, Bryce, Sigmar, Kristjan, Afreen, Esha, Nguyen, Tammy, Randolph, Amanda, Taber, Alexandria, Krzeszowski, Ashley, Robinett, Brittney, Volkin, David B., Grassi, Fabio, Guerrant, Richard, Takeuchi, Ryo, Finrow, Brian, Behnke, Craig, Roberts, James

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IL-28, IL-29 and their class II cytokine receptor IL-28R by Klucher, Kevin M, Sheppard, Paul, Kindsvogel, Wayne, Xu, Wenfeng, Henderson, Katherine, Schlutsmeyer, Stacy, Whitmore, Theodore E, Kuestner, Rolf, Garrigues, Ursula, Birks, Carl, Roraback, Jenny, Ostrander, Craig, Dong, Dennis, Shin, Jinu, Presnell, Scott, Fox, Brian, Haldeman, Betty, Cooper, Emily, Taft, David, Gilbert, Teresa, Grant, Francis J, Tackett, Monica, Krivan, William, McKnight, Gary, Clegg, Chris, Foster, Don

“…Cytokines play a critical role in modulating the innate and adaptive immune systems. Here, we have identified from the human genomic sequence a family of three…”
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Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice by Gross, Jane A, Dillon, Stacey R, Sprecher, Cindy, Hammond, Angela, Bilsborough, Janine, Rosenfeld-Franklin, Maryland, Presnell, Scott R, Haugen, Harald S, Maurer, Mark, Harder, Brandon, Johnston, Janet, Bort, Susan, Mudri, Sherri, Kuijper, Joseph L, Bukowski, Tom, Shea, Pamela, Dong, Dennis L, Dasovich, Maria, Grant, Francis J, Lockwood, Luann, Levin, Steven D, LeCiel, Cosette, Waggie, Kim, Day, Heather, Topouzis, Stavros, Kramer, Janet, Kuestner, Rolf, Chen, Zhi, Foster, Don, Parrish-Novak, Julia

“…T cell-derived cytokines are important in the development of an effective immune response, but when dysregulated they can promote disease. Here we identify a…”
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Abstract 1918: Synergy between epithelial and mesenchymal cells in breast cancer: from mammospheres to predicting patient outcomes by Grosse-Wilde, Anne, d'Herouel, Aymeric, Kuestner, Rolf, Ertaylan, Gokhan, Skupin, Alexander, Huang, Sui, Ozinsky, Adrian

“…Abstract Targeting breast cancer stem cells promises to eliminate the root of metastasis and recurrence and thus to eradicate the ultimate cause of…”
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Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients by Grosse-Wilde, Anne, Kuestner, Rolf E, Skelton, Stephanie M, MacIntosh, Ellie, d'Hérouël, Aymeric Fouquier, Ertaylan, Gökhan, Del Sol, Antonio, Skupin, Alexander, Huang, Sui

“…According to the sequential metastasis model, aggressive mesenchymal (M) metastasis-initiating cells (MICs) are generated by an epithelial-mesenchymal…”
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Francisella tularensis subsp. tularensis Induces a Unique Pulmonary Inflammatory Response: Role of Bacterial Gene Expression in Temporal Regulation of Host Defense Responses. e62412 by Walters, Kathie-Anne, Olsufka, Rachael, Kuestner, Rolf E, Cho, Ji Hoon, Li, Hong, Zornetzer, Gregory A, Wang, Kai, Skerrett, Shawn J, Ozinsky, Adrian

“…Pulmonary exposure to Francisella tularensis is associated with severe lung pathology and a high mortality rate. The lack of induction of classical…”
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