Search Results - "Kuen, René Lai"
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Preparation of parenteral nanocrystal suspensions of etoposide from the excipient free dry state of the drug to enhance in vivo antitumoral properties
Published in Scientific reports (22-10-2020)“…Nanoparticle technology in cancer chemotherapy is a promising approach to enhance active ingredient pharmacology and pharmacodynamics. Indeed, drug…”
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Palladium Nanoparticle-Catalyzed Stereoretentive Cross-Coupling of Alkenyl Sulfides with Grignard Reagents
Published in Organic letters (02-03-2018)“…Reaction conditions allowing a stereoretentive cross-coupling of alkenyl sulfides with Grignard reagents using ligand-free Pd catalysis are discussed here. The…”
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Protease Inhibitor Anti-HIV, Lopinavir, Impairs Placental Endocrine Function
Published in International journal of molecular sciences (12-01-2021)“…Protease Inhibitors (PI e.g., ritonavir (RTV) and lopinavir (LPV)) used to treat pregnant mothers infected by HIV induce prematurity and endocrine…”
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Co-Encapsulation of Fisetin and Cisplatin into Liposomes for Glioma Therapy: From Formulation to Cell Evaluation
Published in Pharmaceutics (26-06-2021)“…(1) Background: Glioblastoma (GBM) is the most frequent cerebral tumor. It almost always relapses and there is no validated treatment for second-line GBM. We…”
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Human Galectin 3 Binding Protein Interacts with Recombinant Adeno-Associated Virus Type 6
Published in Journal of Virology (01-06-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Uptake of Cerium Dioxide Nanoparticles and Impact on Viability, Differentiation and Functions of Primary Trophoblast Cells from Human Placenta
Published in Nanomaterials (Basel, Switzerland) (03-07-2020)“…The human placenta is at the interface between maternal and fetal circulations, and is crucial for fetal development. The nanoparticles of cerium dioxide (CeO2…”
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Characterization of Human Villous and Extravillous Trophoblasts Isolated from First Trimester Placenta
Published in Laboratory investigation (01-09-2001)“…Trophoblasts of the human placenta differentiate along two pathways to give either extravillous cytotrophoblasts (EVCT) with invasive properties and that are…”
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Identification of plasma membrane autoantigens in autoimmune hepatitis type 1 using a proteomics tool
Published in Hepatology (Baltimore, Md.) (01-03-2008)“…Autoimmune hepatitis (AIH) is a liver disease with circulating autoantibodies predominantly directed against widely held cellular components. Because AIH is a…”
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Co-culture of type I and type II pneumocytes as a model of alveolar epithelium
Published in PloS one (27-09-2021)“…The epithelial tissues of the distal lung are continuously exposed to inhaled air, and are of research interest in studying respiratory exposure to both…”
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Formulations for Protecting the Probiotic Saccharomyces boulardii from Degradation in Acidic Condition
Published in Biological & Pharmaceutical Bulletin (01-02-2008)“…Saccharomyces boulardii is a nonpathogenic yeast with proven health benefits, some of them depending on its viability. However, the living yeast is sensitive…”
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Co-encapsulation of fisetin and cisplatin into liposomes: Stability considerations and in vivo efficacy on lung cancer animal model
Published in International journal of pharmaceutics (15-02-2024)“…[Display omitted] Lung cancer is a highly vascularized tumor for which a combination between an antitumor agent, cisplatin, and an antiangiogenic molecule,…”
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Long-term evolution of the epithelial cell secretome in preclinical 3D models of the human bronchial epithelium
Published in Scientific reports (23-03-2021)“…The human bronchial epithelium is the first line of defense against atmospheric particles, pollutants, and respiratory pathogens such as the novel SARS-CoV-2…”
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Neuroinflammation, myelin and behavior: Temporal patterns following mild traumatic brain injury in mice
Published in PloS one (14-09-2017)“…Traumatic brain injury (TBI) results in white matter injury (WMI) that is associated with neurological deficits. Neuroinflammation originating from microglial…”
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Cationic lipid nanoparticle production by microfluidization for siRNA delivery
Published in International journal of pharmaceutics (10-08-2021)“…[Display omitted] Microfluidization has been investigated as a new, scalable, and basic component saving method to produce cationic lipid nanoparticles, in…”
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Phagocytic and Tumor Necrosis Factor Alpha Response of Human Mast Cells following Exposure to Gram-Negative and Gram-Positive Bacteria
Published in Infection and Immunity (01-12-1998)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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How to make siRNA lipoplexes efficient? Add a DNA cargo
Published in Biochimica et biophysica acta (01-04-2009)“…We recently reported an efficient formulation of siRNA targeting TNF-α, that was able to restore immunological balance in a mouse arthritis model following…”
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Effect of Matrigel on Human Extravillous Trophoblasts Differentiation: Modulation of Protease Pattern Gene Expression1
Published in Biology of reproduction (01-11-2002)“…The human placenta is characterized by extensive trophoblast invasion of the uterus. Indeed, extravillous cytotrophoblast cells invade the decidua and the…”
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A new technique of endothelial graft: the femtosecond and excimer lasers‐assisted endothelial keratoplasty (FELEK)
Published in Acta ophthalmologica (Oxford, England) (01-09-2013)Get full text
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Spheroplexes: Hybrid PLGA-cationic lipid nanoparticles, for in vitro and oral delivery of siRNA
Published in Journal of controlled release (01-10-2022)“…Vectorized small interfering RNAs (siRNAs) are widely used to induce gene silencing. Among the delivery systems used, lipid-based particles are the most…”
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Influence of pH conditions on the viability of Saccharomyces boulardii yeast
Published in Journal of general and applied microbiology (2008)“…Saccharomyces boulardii is a probiotic with proven health benefits. However its survival is challenged by gastrointestinal transit, and a ratio between 1 and…”
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