Search Results - "Kuehl, Thomas J."

Placental Toll-like receptor 3 and Toll-like receptor 7/8 activation contributes to preeclampsia in humans and mice by Chatterjee, Piyali, Weaver, Laura E, Doersch, Karen M, Kopriva, Shelley E, Chiasson, Valorie L, Allen, Samantha J, Narayanan, Ajay M, Young, Kristina J, Jones, Kathleen A, Kuehl, Thomas J, Mitchell, Brett M

“…Preeclampsia (PE) is a pregnancy-specific hypertensive syndrome characterized by excessive maternal immune system activation, inflammation, and endothelial…”
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Hyperglycemia impairs cytotrophoblast function via stress signaling by R. Cawyer, Chase, MD, MBA, Horvat, Darijana, BS, Leonard, Dean, Allen, Steven R., MD, Jones, Richard O., MD, Zawieja, David C., PhD, Kuehl, Thomas J., PhD, Uddin, Mohammad N., PhD

“…Objective Diabetes mellitus is a risk factor for preeclampsia. Cytotrophoblast (CTB) invasion is facilitated from the conversion of plasminogen to plasmin by…”
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Pravastatin Protects Cytotrophoblasts from Hyperglycemia-Induced Preeclampsia Phenotype by Pantho, Ahmed F, Mohamed, Sara, Govande, Janhavi V, Rane, Riddhi, Vora, Niraj, Kelso, Kelsey R, Kuehl, Thomas J, Lindheim, Steven R, Uddin, Mohammad N

“…There are no effective therapies to prevent preeclampsia (PE). Pravastatin shows promise by attenuating processes associated with PE such as decreased…”
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Elevation of (Pro)Renin and (Pro)Renin Receptor in Preeclampsia by Thomason, Jessica, Reyes, Michelle, Allen, Steven R., Jones, Richard O., Beeram, Madhava R., Kuehl, Thomas J., Suzuki, Fumiaki, Uddin, Mohammad Nasir

“…OBJECTIVE Preeclampsia (preE), a syndrome of hypertension, proteinuria, and edema, has many elusive triggers. The renin–angiotensin system has been implicated…”
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Mechanism of Marinobufagenin-Induced Hyperpermeability of Human Brain Microvascular Endothelial Cell Monolayer: A Potential Pathogenesis of Seizure in Preeclampsia by Pantho, Ahmed F, Singh, Manisha, Afroze, Syeda H, Kelso, Kelsey R, Ehrig, Jessica C, Vora, Niraj, Kuehl, Thomas J, Lindheim, Steven R, Uddin, Mohammad N

“…Preeclampsia (preE) is a hypertensive disorder in pregnancies. It is the third leading cause of mortality among pregnant women and fetuses worldwide, and there…”
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Long-term histologic response to synthetic and biologic graft materials implanted in the vagina and abdomen of a rabbit model by Pierce, Lisa M., DSc, Rao, Arundhati, MD, PhD, Baumann, Shannon S., AA, Glassberg, Jocylen E., MD, Kuehl, Thomas J., PhD, Muir, Tristi W., MD

“…Objective We sought to evaluate the effects of graft type, site of implantation, and ovariectomy on the long-term histologic response to graft materials used…”
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Randomized trial of cesarean vs vaginal delivery for effects on the pelvic floor in squirrel monkeys by Lindo, Fiona M., MD, MPH, Carr, Emily S., BS, Reyes, Michelle, BA, Gendron, Jilene M., RT (R), Ruiz, Julio C., DVM, Parks, Virginia L., BS, Kuehl, Thomas J., PhD, Larsen, Wilma I., MD

“…Background Vaginal delivery is a risk factor in pelvic floor disorders. We previously described changes in the pelvic floor associated with pregnancy and…”
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Biomechanical properties of synthetic and biologic graft materials following long-term implantation in the rabbit abdomen and vagina by Pierce, Lisa M., DSc, Grunlan, Melissa A., PhD, Hou, Yaping, BS, Baumann, Shannon S., AA, Kuehl, Thomas J., PhD, Muir, Tristi W., MD

“…Objective We sought to evaluate the effects of anatomic location and ovariectomy on biomechanical properties of synthetic and biologic graft materials after…”
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Histologic response of porcine collagen-coated and uncoated polypropylene grafts in a rabbit vagina model by Huffaker, R. Keith, MD, Muir, Tristi W., MD, Rao, Arundhati, MD, PhD, Baumann, Shannon S., AA, Kuehl, Thomas J., PhD, Pierce, Lisa M., DSc

“…Objective The purpose of this study was to determine whether the host tissue response in the rabbit vagina differs for 2 synthetic graft materials that are…”
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Protocol for a multicenter randomized, double blind, controlled pilot trial of higher neural function in overactive bladder patients after anticholinergic, beta-3 adrenergic agonist, or placebo by High, Rachel A., Danford, Jill M., Shi, Zhaoyue, Karmonik, Christof, Kuehl, Thomas J., Bird, Erin T., Khavari, Rose

“…Overactive bladder (OAB) syndrome has a negative impact on quality of life and prevalence increases with advanced age. Anticholinergics (AC) and beta-3…”
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Innervation of the female levator ani muscles by Barber, Matthew D., Bremer, Ronald E., Thor, Karl B., Dolber, Paul C., Kuehl, Thomas J., Coates, Kimberly W.

“…Objective: The objective of this study was to characterize the innervation of the human female levator ani muscles. Study Design: Detailed dissections of the…”
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A pilot study in intraparenchymal therapy delivery in the prostate: a comparison of delivery with a porous needle vs standard needle by Brady, Martin L, Coffield, King Scott, Kuehl, Thomas J, Raghavan, Raghu, Speights, Jr, V O, Patel, Belur, Wilson, Scott, Wilson, Mike, Odland, Rick M

“…New biologic therapies directly injected into the prostate are in clinical trials for prostatic diseases. There is a need to understand distribution of…”
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Utilization of cryopreserved sperm cells based on the indication for storage by Machen, Graham Luke, Harris, Stephanie E, Bird, Erin T, Brown, Monica L, Ingalsbe, Dale A, East, Milaida M, Reyes, Michelle, Kuehl, Thomas J

“…Cryopreservation of sperm from human semen has been available since the 1950s. The actual utilization of available cryopreservation technology has been…”
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Effect of estrogen replacement on the histologic response to polypropylene mesh implanted in the rabbit vagina model by Higgins, Edmund W., MD, Rao, Arundhati, MD, PhD, Baumann, Shannon S, James, Rebecca L., MD, Kuehl, Thomas J., PhD, Muir, Tristi W., MD, Pierce, Lisa M., DSc

“…Objective The aim of this study was to determine the effect of estrogen replacement after ovariectomy on the histologic response to polypropylene mesh…”
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Effects of bilateral levator ani nerve injury on pelvic support in the female squirrel monkey by Pierce, Lisa M., DSc, Coates, Kimberly W., MD, Kramer, Lori A., MD, Bradford, Jason C., MD, Thor, Karl B., PhD, Kuehl, Thomas J., PhD

“…Objective To determine whether experimental denervation of the levator ani (LA) and its subsequent atrophy contribute to the development of pelvic organ…”
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Pelvic floor changes in the first term pregnancy and postpartum period by Wu, Emily, Kuehl, Thomas J., Gendron, Jilene M., White, Wendy, Yandell, Paul M.

“…Objective To follow a prospective cohort of women during their first term pregnancy to elucidate the nature and timing of changes to the pelvic floor during…”
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Levator ani muscle and connective tissue changes associated with pelvic organ prolapse, parity, and aging in the squirrel monkey: a histologic study by Pierce, Lisa M., DSc, Baumann, Shannon, AA, Rankin, Michelle R., BA, Wasserman, Richard M., MD, Biaggi, Arabella, MD, Kuehl, Thomas J., PhD, Coates, Kimberly W., MD

“…Objective This study was undertaken to evaluate histologically the levator ani muscle and paravaginal attachments in squirrel monkeys with and without pelvic…”
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Postoperative prophylactic antibiotics for retropubic mid-urethral slings by Wu, Emily, Kuehl, Thomas J., Danford, Jill M., Bird, Erin T., Yandell, Paul M.

“…Objectives and hypothesis The primary objective is to measure the difference in urinary tract infection (UTI) rates within 6  weeks of placement of a…”
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Distribution and immunohistochemical characterization of primary afferent neurons innervating the levator ani muscle of the female squirrel monkey by Pierce, Lisa M., Rankin, Michelle R., Foster, Raymond T., Dolber, Paul C., Coates, Kimberly W., Kuehl, Thomas J., Thor, Karl B.

“…This study was undertaken to examine the neurofilament and neurochemical composition of subpopulations of primary afferent neurons innervating the levator ani…”
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Retropubic mid‐urethral slings and de novo urinary urgency and frequency: The role of retropubic hematomas by Wu, Emily, High, Rachel, Lewis, Christopher, Kuehl, Thomas J., Danford, Jill M., Yandell, Paul M.

“…Aims This is a prospective cohort study comparing de novo lower urinary tract symptoms (LUTS) in subjects undergoing a retropubic mid‐urethral sling who either…”
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