Search Results - "Kuehl, Kathleen A."

GP38-targeting monoclonal antibodies protect adult mice against lethal Crimean-Congo hemorrhagic fever virus infection by Golden, Joseph W, Shoemaker, Charles J, Lindquist, Michael E, Zeng, Xiankun, Daye, Sharon P, Williams, Janice A, Liu, Jun, Coffin, Kayla M, Olschner, Scott, Flusin, Olivier, Altamura, Louis A, Kuehl, Kathleen A, Fitzpatrick, Collin J, Schmaljohn, Connie S, Garrison, Aura R

“…Crimean-Congo hemorrhagic fever virus (CCHFV) is an important human pathogen. Limited evidence suggests that antibodies can protect humans against lethal CCHFV…”
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siRNA Screen Identifies Trafficking Host Factors that Modulate Alphavirus Infection by Radoshitzky, Sheli R, Pegoraro, Gianluca, Chī, Xi Olì, D Ng, Lián, Chiang, Chih-Yuan, Jozwick, Lucas, Clester, Jeremiah C, Cooper, Christopher L, Courier, Duane, Langan, David P, Underwood, Knashka, Kuehl, Kathleen A, Sun, Mei G, Caì, Yíngyún, Yú, Shu Qìng, Burk, Robin, Zamani, Rouzbeh, Kota, Krishna, Kuhn, Jens H, Bavari, Sina

“…Little is known about the repertoire of cellular factors involved in the replication of pathogenic alphaviruses. To uncover molecular regulators of alphavirus…”
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A Francisella novicida Mutant, Lacking the Soluble Lytic Transglycosylase Slt, Exhibits Defects in Both Growth and Virulence by Bachert, Beth A, Biryukov, Sergei S, Chua, Jennifer, Rodriguez, Sabrina A, Toothman, Jr, Ronald G, Cote, Christopher K, Klimko, Christopher P, Hunter, Melissa, Shoe, Jennifer L, Williams, Janice A, Kuehl, Kathleen A, Biot, Fabrice V, Bozue, Joel A

“…is the causative agent of tularemia and has gained recent interest as it poses a significant biothreat risk. is commonly used as a laboratory surrogate for…”
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A Model for the Production of Regulatory Grade Viral Hemorrhagic Fever Exposure Stocks: From Field Surveillance to Advanced Characterization of SFTSV by Perez-Sautu, Unai, Gu, Se Hun, Caviness, Katie, Song, Dong Hyun, Kim, Yu-Jin, Paola, Nicholas Di, Lee, Daesang, Klein, Terry A, Chitty, Joseph A, Nagle, Elyse, Kim, Heung-Chul, Chong, Sung-Tae, Beitzel, Brett, Reyes, Daniel S, Finch, Courtney, Byrum, Russ, Cooper, Kurt, Liang, Janie, Kuhn, Jens H, Zeng, Xiankun, Kuehl, Kathleen A, Coffin, Kayla M, Liu, Jun, Oh, Hong Sang, Seog, Woong, Choi, Byung-Sub, Sanchez-Lockhart, Mariano, Palacios, Gustavo, Jeong, Seong Tae

“…Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging human pathogen, endemic in areas of China, Japan, and the Korea (KOR). It is primarily…”
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Persistent Marburg Virus Infection in the Testes of Nonhuman Primate Survivors by Coffin, Kayla M., Liu, Jun, Warren, Travis K., Blancett, Candace D., Kuehl, Kathleen A., Nichols, Donald K., Bearss, Jeremy J., Schellhase, Christopher W., Retterer, Cary J., Weidner, Jessica M., Radoshitzky, Sheli R., Brannan, Jennifer M., Cardile, Anthony P., Dye, John M., Palacios, Gustavo, Sun, Mei G., Kuhn, Jens H., Bavari, Sina, Zeng, Xiankun

“…Sexual transmission of filoviruses was first reported in 1968 after an outbreak of Marburg virus (MARV) disease and recently caused flare-ups of Ebola virus…”
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Accurate virus quantitation using a Scanning Transmission Electron Microscopy (STEM) detector in a scanning electron microscope by Blancett, Candace D., Fetterer, David P., Koistinen, Keith A., Morazzani, Elaine M., Monninger, Mitchell K., Piper, Ashley E., Kuehl, Kathleen A., Kearney, Brian J., Norris, Sarah L., Rossi, Cynthia A., Glass, Pamela J., Sun, Mei G.

“…•Provides a simple and effective experimental set up for Electron Microscopy virus preparation.•Provides a reproducible technique for virus concentration…”
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The D-alanyl-d-alanine carboxypeptidase enzyme is essential for virulence in the Schu S4 strain of Francisella tularensis and a dacD mutant is able to provide protection against a pneumonic challenge by Kijek, Todd M., Mou, Sherry, Bachert, Beth A., Kuehl, Kathleen A., Williams, Janice A., Daye, Sharon P., Worsham, Patricia L., Bozue, Joel A.

“…Low molecular mass penicillin binding proteins (LMM PBP) are bacterial enzymes involved in the final steps of peptidoglycan biosynthesis. In Escherichia coli,…”
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Preparation of viral samples within biocontainment for ultrastructural analysis: Utilization of an innovative processing capsule for negative staining by Monninger, Mitchell K., Nguessan, Chrystal A., Blancett, Candace D., Kuehl, Kathleen A., Rossi, Cynthia A., Olschner, Scott P., Williams, Priscilla L., Goodman, Steven L., Sun, Mei G.

“…•Recommend a revolutionary method for preparing virus sample in biocontainment.•Evaluate TEM image qualities according to different virus inactivation…”
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Cross-protection conferred by filovirus virus-like particles containing trimeric hybrid glycoprotein by Martins, Karen, Carra, John H, Cooper, Christopher L, Kwilas, Steven A, Robinson, Camenzind G, Shurtleff, Amy C, Schokman, Rowena D, Kuehl, Kathleen A, Wells, Jay B, Steffens, Jesse T, van Tongeren, Sean A, Hooper, Jay W, Bavari, Sina

“…Filoviruses are causative agents of hemorrhagic fever, and to date no effective vaccine or therapeutic has been approved to combat infection. Filovirus…”
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Utilization of Capsules for Negative Staining of Viral Samples within Biocontainment by Blancett, Candace D, Monninger, Mitchell K, Nguessan, Chrystal A, Kuehl, Kathleen A, Rossi, Cynthia A, Olschner, Scott P, Williams, Priscilla L, Goodman, Steven L, Sun, Mei G

“…Transmission electron microscopy (TEM) is used to observe the ultrastructure of viruses and other microbial pathogens with nanometer resolution. Most…”
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Utilization of Capsules for Negative Staining of Viral Samples within Biocontainment by Blancett, Candace D., Monninger, Mitchell K., Nguessan, Chrystal A., Kuehl, Kathleen A., Rossi, Cynthia A., Olschner, Scott P., Williams, Priscilla L., Goodman, Steven L., Sun, Mei G.

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