Search Results - "Kudová, Eva"

Modulation of Muscarinic Signalling in the Central Nervous System by Steroid Hormones and Neurosteroids by Szczurowska, Ewa, Szánti-Pintér, Eszter, Chetverikov, Nikolai, Randáková, Alena, Kudová, Eva, Jakubík, Jan

“…Muscarinic acetylcholine receptors expressed in the central nervous system mediate various functions, including cognition, memory, or reward. Therefore,…”
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Anti-Nociceptive Effects of Sphingomyelinase and Methyl-Beta-Cyclodextrin in the Icilin-Induced Mouse Pain Model by Horváth, Ádám, Steib, Anita, Nehr-Majoros, Andrea, Kántás, Boglárka, Király, Ágnes, Racskó, Márk, Tóth, Balázs István, Szánti-Pintér, Eszter, Kudová, Eva, Skoda-Földes, Rita, Helyes, Zsuzsanna, Szőke, Éva

“…The thermo- and pain-sensitive Transient Receptor Potential Melastatin 3 and 8 (TRPM3 and TRPM8) ion channels are functionally associated in the lipid rafts of…”
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Neurosteroids and steroid hormones are allosteric modulators of muscarinic receptors by Dolejší, Eva, Szánti-Pintér, Eszter, Chetverikov, Nikolai, Nelic, Dominik, Randáková, Alena, Doležal, Vladimír, Kudová, Eva, Jakubík, Jan

“…The membrane cholesterol was found to bind and modulate the function of several G-protein coupled receptors including muscarinic acetylcholine receptors. We…”
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Neuroactive steroids, WIN-compounds and cholesterol share a common binding site on muscarinic acetylcholine receptors by Dolejší, Eva, Chetverikov, Nikolai, Szánti-Pintér, Eszter, Nelic, Dominik, Randáková, Alena, Doležal, Vladimír, El-Fakahany, Esam E., Kudová, Eva, Jakubík, Jan

“…[Display omitted] Endogenous neurosteroids and their synthetic analogues-neuroactive steroids-have been found to bind to muscarinic acetylcholine receptors and…”
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Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms by Chern, Chian-Ru, Lauková, Marcela, Schonwald, Antonia, Kudová, Eva, Chodounská, Hana, Chern, Chian-Jiang, Shakarjian, Michael P, Velíšková, Jana, Velíšek, Libor

“…Neurosteroids are investigated as effective antidotes for the poisoning induced by tetramethylenedisulfotetramine (TMDT) as well as treatments for epileptic…”
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The Endocannabinoid System - The Prediction of Spontaneous Preterm Birth in High-Risk Women: Protocol of a Study by Pařízek, A, Hill, M, Dušková, M, Kolátorová, L, Suchopár, J, Šimják, P, Anderlová, K, Kudová, E, Rogalewicz, V, Vacek, J, Koudelková, M, Chloupková, R, Alblová, M, Pařízková, P, Laštůvka, Z, Barták, M

“…Spontaneous preterm birth (sPTB) is a major cause of perinatal morbidity and mortality, even in developed countries. Prediction of sPTB is therefore a valuable…”
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Distributions of therapeutically promising neurosteroids in cellular membranes by Riedlová, Kamila, Nekardová, Michaela, Kačer, Petr, Syslová, Kamila, Vazdar, Mario, Jungwirth, Pavel, Kudová, Eva, Cwiklik, Lukasz

“…•Pregnanolone sulfate (PAS) and pregnanolone glutamate (PAG) inhibit N-Methyl-Daspartate receptors (NMDARs).•PAG is a novel synthetic steroidal inhibitor but…”
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Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides by Brejchova, Kristyna, Radner, Franz Peter Walter, Balas, Laurence, Paluchova, Veronika, Cajka, Tomas, Chodounska, Hana, Kudova, Eva, Schratter, Margarita, Schreiber, Renate, Durand, Thierry, Zechner, Rudolf, Kuda, Ondrej

“…Branched esters of palmitic acid and hydroxy stearic acid are antiinflammatory and antidiabetic lipokines that belong to a family of fatty acid (FA) esters of…”
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Sulfo-N-succinimidyl Oleate (SSO) Inhibits Fatty Acid Uptake and Signaling for Intracellular Calcium via Binding CD36 Lysine 164 by Kuda, Ondrej, Pietka, Terri A., Demianova, Zuzana, Kudova, Eva, Cvacka, Josef, Kopecky, Jan, Abumrad, Nada A.

“…FAT/CD36 is a multifunctional glycoprotein that facilitates long-chain fatty acid (FA) uptake by cardiomyocytes and adipocytes and uptake of oxidized low…”
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Allosteric Modulation of Muscarinic Receptors by Cholesterol, Neurosteroids and Neuroactive Steroids by Szczurowska, Ewa, Szánti-Pintér, Eszter, Randáková, Alena, Jakubík, Jan, Kudova, Eva

“…Muscarinic acetylcholine receptors are membrane receptors involved in many physiological processes. Malfunction of muscarinic signaling is a cause of various…”
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Neurosteroids: Structure-Uptake Relationships and Computational Modeling of Organic Anion Transporting Polypeptides (OATP)1A2 by Adla, Santosh Kumar, Tonduru, Arun Kumar, Kronenberger, Thales, Kudova, Eva, Poso, Antti, Huttunen, Kristiina M

“…In this study, we investigated the delivery of synthetic neurosteroids into MCF-7 human breast adenocarcinoma cells via Organic Anionic Transporting…”
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Epipregnanolone as a Positive Modulator of GABAA Receptor in Rat Cerebellar and Hippocampus Neurons by Bukanova, Julia, Solntseva, Elena, Kondratenko, Rodion, Kudova, Eva

“…Epipregnanolone (3β-hydroxy-5β-pregnan-20-one, Epi) is an endogenous steroid with important physiological effects and high affinity for GABAA receptors. The…”
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Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor by Carazo, Alejandro, Hyrsova, Lucie, Dusek, Jan, Chodounska, Hana, Horvatova, Alzbeta, Berka, Karel, Bazgier, Vaclav, Gan-Schreier, Hongying, Chamulitrat, Waleé, Kudova, Eva, Pavek, Petr

“…[Display omitted] •Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of PXR.•Acetylated DCA and CA enhance PXR target genes…”
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Neurosteroids as Selective Inhibitors of Glycine Receptor Activity: Structure-Activity Relationship Study on Endogenous Androstanes and Androstenes by Bukanova, Julia V, Solntseva, Elena I, Kudova, Eva

“…The ability of androstane and androstene neurosteroids with modifications at C-17, C-5, and C-3 (compounds - ) to influence the functional activity of…”
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(E)-7-Ethylidene-lithocholic Acid (7-ELCA) Is a Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimulating Glucagon-like Peptide-1 Secretion From Enteroendocrine Cells by Stefela, Alzbeta, Kaspar, Miroslav, Drastik, Martin, Kronenberger, Thales, Micuda, Stanislav, Dracinsky, Martin, Klepetarova, Blanka, Kudova, Eva, Pavek, Petr

“…Bile acids (BAs) are key signaling steroidal molecules that regulate glucose, lipid, and energy homeostasis via interactions with the farnesoid X receptor…”
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The Neuroactive Steroid Pregnanolone Glutamate: Anticonvulsant Effect, Metabolites and Its Effect on Neurosteroid Levels in Developing Rat Brains by Kudova, Eva, Mares, Pavel, Hill, Martin, Vondrakova, Katerina, Tsenov, Grygoriy, Chodounska, Hana, Kubova, Hana, Vales, Karel

“…Pregnanolone glutamate (PA-G) is a neuroactive steroid that has been previously demonstrated to be a potent neuroprotective compound in several biological…”
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Surface Expression, Function, and Pharmacology of Disease-Associated Mutations in the Membrane Domain of the Human GluN2B Subunit by Vyklicky, Vojtech, Krausova, Barbora, Cerny, Jiri, Ladislav, Marek, Smejkalova, Tereza, Kysilov, Bohdan, Korinek, Miloslav, Danacikova, Sarka, Horak, Martin, Chodounska, Hana, Kudova, Eva, Vyklicky, Ladislav

“…N-methyl-D-aspartate receptors (NMDARs), glutamate-gated ion channels, mediate signaling at the majority of excitatory synapses in the nervous system. Recent…”
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C‑3 Steroidal Hemiesters as Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 10 by Hanzlova, Michaela, Slavikova, Barbora, Morozovova, Marina, Musilek, Kamil, Rotterova, Aneta, Zemanová, Lucie, Kudova, Eva

“…17β-HSD10 is a mitochondrial enzyme that catalyzes the steroidal oxidation of a hydroxy group to a keto group and, thus, is involved in maintaining steroid…”
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Correction to “C‑3 Steroidal Hemiesters as Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 10” by Hanzlova, Michaela, Slavikova, Barbora, Morozovova, Marina, Musilek, Kamil, Rotterova, Aneta, Zemanová, Lucie, Kudova, Eva

“…[This corrects the article DOI: 10.1021/acsomega.3c10148.]…”
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Stereoselective Reduction of Steroidal 4‑Ene-3-ketones in the Presence of Biomass-Derived Ionic Liquids Leading to Biologically Important 5β-Steroids by Szánti-Pintér, Eszter, Jirkalová, Lada, Pohl, Radek, Bednárová, Lucie, Kudova, Eva

“…The stereoselective reduction of the steroidal 4-ene-3-ketone moiety (enone) affords the 5β-steroid backbone that is a key structural element of biologically…”
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