Search Results - "Kudo, Ikuru"

The regulation mechanisms of AhR by molecular chaperone complex by Kudo, Ikuru, Hosaka, Miki, Haga, Asami, Tsuji, Noriko, Nagata, Yuhtaroh, Okada, Hirotaka, Fukuda, Kana, Kakizaki, Yuka, Okamoto, Tomoya, Grave, Ewa, Itoh, Hideaki

“…The AhR, so called the dioxin receptor, is a member of the nuclear receptor superfamily. The ligand-free AhR forms a cytosolic protein complex with the…”
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Nutrient Condition in the Microenvironment Determines Essential Metabolisms of CD8+ T Cells for Enhanced IFNγ Production by Metformin by Chao, Ruoyu, Nishida, Mikako, Yamashita, Nahoko, Tokumasu, Miho, Zhao, Weiyang, Kudo, Ikuru, Udono, Heiichiro

“…Metformin (Met), a first-line drug for type 2 diabetes, lowers blood glucose levels by suppressing gluconeogenesis in the liver, presumably through the liver…”
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Blocking EP4 down-regulates tumor metabolism and synergizes with anti-PD-1 therapy to activate natural killer cells in a lung adenocarcinoma model by Tokumasu, Miho, Nishida, Mikako, Kawaguchi, Takamasa, Kudo, Ikuru, Kotani, Tohru, Takeda, Kazuhiko, Yoshida, Takao, Udono, Heiichiro

“…Abstract Prostaglandin E2 (PGE2), a product of the cyclooxygenase (COX) pathway, is produced by tumors and surrounding stromal cells. It stimulates tumor…”
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Restriction of protein synthesis abolishes senescence features at cellular and organismal levels by Takauji, Yuki, Wada, Takumi, Takeda, Asuka, Kudo, Ikuru, Miki, Kensuke, Fujii, Michihiko, Ayusawa, Dai

“…Cellular senescence or its equivalence is induced by treatment of cells with an appropriate inducer of senescence in various cell types. Mild restriction of…”
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Molecular basis for premature senescence induced by surfactants in normal human cells by Yamakami, Yoshimi, Miki, Kensuke, Yonekura, Ryuzo, Kudo, Ikuru, Fujii, Michihiko, Ayusawa, Dai

“…Sublethal doses of surfactants as exemplified by NP-40 clearly induce premature senescence in normal human cells. To understand molecular basis for this…”
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High dose of antibiotic colistin induces oligomerization of molecular chaperone HSP90 by Togashi, Shuntaro, Takahashi, Kyosuke, Tamura, Arisa, Toyota, Ikumi, Hatakeyama, Shiori, Komatsuda, Atsushi, Kudo, Ikuru, Sasaki Kudoh, Erina, Okamoto, Tomoya, Haga, Asami, Miyamoto, Asuka, Grave, Ewa, Sugawara, Taku, Shimizu, Hiroaki, Itoh, Hideaki

“…Colistin is an antimicrobial cationic peptide that belongs to the polymyxin family. Colistin was clinically used for the treatment of gram-negative infections…”
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HSP60 possesses a GTPase activity and mediates protein folding with HSP10 by Okamoto, Tomoya, Yamamoto, Hiroshi, Kudo, Ikuru, Matsumoto, Kazuya, Odaka, Masafumi, Grave, Ewa, Itoh, Hideaki

“…The mammalian molecular chaperone, HSP60, plays an essential role in protein homeostasis through mediating protein folding and assembly. The structure and…”
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GNG11 (G-protein subunit γ 11) suppresses cell growth with induction of reactive oxygen species and abnormal nuclear morphology in human SUSM-1 cells by Takauji, Yuki, Kudo, Ikuru, En, Atsuki, Matsuo, Ryo, Hossain, Mohammad Nazir, Nakabayashi, Kazuhiko, Miki, Kensuke, Fujii, Michihiko, Ayusawa, Dai

“…Enforced expression of GNG11, G-protein subunit γ 11, induces cellular senescence in normal human diploid fibroblasts. We here examined the effect of the…”
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Dual roles of ERK1/2 in cellular senescence induced by excess thymidine in HeLa cells by Kudo, Ikuru, Nozawa, Megumi, Miki, Kensuke, Takauji, Yuki, En, Atsuki, Fujii, Michihiko, Ayusawa, Dai

“…DNA damage response is crucially involved in cellular senescence. We have previously shown that excess thymidine, which stalls DNA replication forks, induces…”
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