Search Results - "Kuckuck, Irina"

In Vitro Evaluation of Humanized/De-immunized Anti-PSMA Immunotoxins for the Treatment of Prostate Cancer by Michalska, Marta, Schultze-Seemann, Susanne, Kuckuck, Irina, Wolf, Philipp

“…We generated humanized/de-immunized immunotoxins targeting the prostate-specific membrane antigen (PSMA) and tested their cytotoxic activity against prostate…”
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Epidermal Growth Factor Based Targeted Toxin for the Treatment of Bladder Cancer by Masilamani, Anie Priscilla, Fischer, Alexandra, Schultze-Seemann, Susanne, Kuckuck, Irina, Wolf, Isis, Dressler, Franz Friedrich, Gratzke, Christian, Wolf, Philipp

“…Reports on over-expression of the epidermal growth factor receptor (EGFR) in bladder cancer and its function in tumorigenesis have suggested to target this…”
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Impact of Methadone on Cisplatin Treatment of Bladder Cancer Cells by Michalska, Marta, Schultze-Seemann, Susanne, Kuckuck, Irina, Katzenwadel, Arndt, Wolf, Philipp

“…Cisplatin-based chemotherapy is the treatment of choice for advanced bladder cancer. Since many tumor cells show inherent or acquired cisplatin resistance,…”
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Synergistic cytotoxicity of a prostate cancer-specific immunotoxin in combination with the BH3 mimetic ABT-737 by Noll, Theresa, Schultze-Seemann, Susanne, Kuckuck, Irina, Michalska, Marta, Wolf, Philipp

“…In many tumors, including prostate cancer, anti-apoptotic members of the Bcl-2 family are overexpressed and cause cell death resistance, which is a typical…”
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An Anti-PSMA Immunotoxin Reduces Mcl-1 and Bcl2A1 and Specifically Induces in Combination with the BAD-Like BH3 Mimetic ABT-737 Apoptosis in Prostate Cancer Cells by Masilamani, Anie P., Dettmer-Monaco, Viviane, Monaco, Gianni, Cathomen, Toni, Kuckuck, Irina, Schultze-Seemann, Susanne, Huber, Nathalie, Wolf, Philipp

“…Background: Upregulation of anti-apoptotic Bcl-2 proteins in advanced prostate cancer leads to therapeutic resistance by prevention of cell death. New…”
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