Search Results - "Kuchovska, Eliska"
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Novel Förster Resonance Energy Transfer probe with quantum dot for a long-time imaging of active caspases inside individual cells
Published in Analytica chimica acta (01-08-2023)“…With the goal to investigate biological phenomena at a single-cell level, we designed, synthesized and tested a molecular probe based on Förster resonance…”
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Comparison of imidacloprid, propiconazole, and nanopropiconazole effects on the development, behavior, and gene expression biomarkers of the Pacific oyster (Magallana gigas)
Published in The Science of the total environment (10-04-2021)“…Coastal areas are final recipients of various contaminants including pesticides. The effects of pesticides on non-target organisms are often unclear,…”
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Pesticide mixture toxicity assessment through in situ and laboratory approaches using embryo-larval stages of the pacific oyster (Magallana gigas)
Published in Marine environmental research (01-07-2021)“…Worsened state of oysters in French Arcachon Bay, demand an investigation of possible causes. This study evaluated the effects of an environmentally relevant…”
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Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation
Published in Frontiers in toxicology (02-03-2022)“…There is a call for a paradigm shift in developmental neurotoxicity (DNT) evaluation, which demands the implementation of faster, more cost-efficient, and…”
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The Current Status and Work of Three Rs Centres and Platforms in Europe
Published in Alternatives to Laboratory Animals (01-11-2022)“…The adoption of Directive 2010/63/EU on the protection of animals used for scientific purposes has given a major push to the formation of Three Rs initiatives…”
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Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps
Published in Frontiers in toxicology (08-03-2024)“…The Adverse Outcome Pathway (AOP) concept facilitates rapid hazard assessment for human health risks. AOPs are constantly evolving, their number is growing,…”
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Transcriptomic characterization of 2D and 3D human induced pluripotent stem cell-based in vitro models as New Approach Methodologies for developmental neurotoxicity testing
Published in Toxicology (Amsterdam) (01-01-2025)“…The safety and developmental neurotoxicity (DNT) potential of chemicals remain critically understudied due to limitations of current in vivo testing…”
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Application of AOPs to assist regulatory assessment of chemical risks – Case studies, needs and recommendations
Published in Environmental research (15-01-2023)“…While human regulatory risk assessment (RA) still largely relies on animal studies, new approach methodologies (NAMs) based on in vitro, in silico or…”
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SOC-II-09 First steps for creating an ontology for cognitive function defects for regulatory application
Published in Toxicology letters (01-09-2022)Get full text
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Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps
Published in Frontiers in toxicology (08-03-2024)“…Introduction: The Adverse Outcome Pathway (AOP) concept facilitates rapid hazard assessment for human health risks. AOPs are constantly evolving, their number…”
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