Search Results - "Kuchmerovska, Tamara"

Vitamin D deficiency induces the excitation/inhibition brain imbalance and the proinflammatory shift by Kasatkina, Ludmila A., Tarasenko, Alla S., Krupko, Olga O., Kuchmerovska, Tamara M., Lisakovska, Olha O., Trikash, Irene O.

“…Synaptic dysfunction under vitamin D deficiency [Display omitted] •Vitamin D3 deficiency predisposes to development of several neurological disorders.•Vitamin…”
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Sex-related differences in plasma amino acids of patients with ST-elevation myocardial infarction and glycine as risk marker of acute heart failure with preserved ejection fraction by Iaremenko, Oleg B., Iordanova, Nataliia Kh, Dudka, Petro F., Kuchmerovska, Tamara M.

“…Nowadays, the problem of preventing acute heart failure (AHF) in patients with ST-elevation myocardial infarction (STEMI) and preserved left-ventricular…”
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Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative–nitrosative stress and p38 MAPK activation by Stavniichuk, Roman, Drel, Viktor R., Shevalye, Hanna, Maksimchyk, Yury, Kuchmerovska, Tamara M., Nadler, Jerry L., Obrosova, Irina G.

“…With the consideration of the multifactorial etiology of diabetic peripheral neuropathy, an ideal drug or drug combination should target at least several key…”
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Nicotinamide prevention in diabetes-induced alterations in the rat liver by Kuchmerovska, Tamara, Yanitska, Lesya, Horkunenko, Oksana, Guzyk, Mykhailo, Tykhonenko, Tetiana, Pryvrotska, Irina

“…The study was performed to elucidate whether nicotinamide (NAm) can attenuate the diabetes-induced liver damage by correction of ammonia detoxifying function…”
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The parp-1 and bax genes as potential targets for treatment of the heart functioning impairments induced by type 1 diabetes mellitus by Kuchmerovska, Tamara, Guzyk, Mykhailo, Tykhonenko, Tetiana, Yanitska, Lesya, Pryvrotska, Irina, Diakun, Kateryna

“…The present study was designed to assess whether apoptosis-related genes as and could be targets for treatment of diabetes mellitus and whether vitamin D may…”
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Poly(ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors Reduce Reactive Gliosis and Improve Angiostatin Levels in Retina of Diabetic Rats by Guzyk, Mykhailo M., Tykhomyrov, Artem A., Nedzvetsky, Victor S., Prischepa, Irina V., Grinenko, Tatiana V., Yanitska, Lesya V., Kuchmerovska, Tamara M.

“…Diabetic retinopathy (DR) is a multifactorial disease characterized by reactive gliosis and disbalance of angiogenesis regulators, contributing to endothelial…”
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Poly(ADP-ribose)polymerase inhibition counteracts renal hypertrophy and multiple manifestations of peripheral neuropathy in diabetic Akita mice by Drel, Viktor, Pacher, Pal, Stavniichuk, Roman, Xu, Weizheng, Zhang, Jie, Kuchmerovska, Tamara, Slusher, Barbara, Obrosova, Irina

“…Poly(ADP-ribose) polymerase (PARP) activation has been implicated in the pathogenesis of diabetic complications, including nephropathy and peripheral…”
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Nicotinamide and Nicotinoyl-Gamma-Aminobutyric Acid as Neuroprotective Agents Against Type 1 Diabetes-Induced Nervous System Impairments in Rats by Kuchmerovska, Tamara, Tykhonenko, Tetiana, Yanitska, Lesya, Savosko, Serhiy, Pryvrotska, Iryna

“…Diabetes is a multifunctional chronic disease that affects both the central and/or peripheral nervous systems. This study assessed whether nicotinamide (NAm)…”
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Modulatory effects of vitamin B3 and its derivative on the levels of apoptotic and vascular regulators and cytoskeletal proteins in diabetic rat brain as signs of neuroprotection by Tykhonenko, Tetiana, Guzyk, Mykhailo, Tykhomyrov, Artem, Korsa, Victoria, Yanitska, Lesya, Kuchmerovska, Tamara

“…Beneficial effects of nicotinamide (NAm) and its derivates have been earlier shown in animal models of diabetes mellitus (DM), but the mechanisms of their…”
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Diabetes-Induced Impairments of the Exocytosis Process and the Effect of Gabapentin: The Link with Cholesterol Level in Neuronal Plasma Membranes by Trikash, Irene, Gumenyuk, Vitaliy, Kuchmerovska, Tamara

“…Diabetic neuropathy represents one of the most prevalent complications of diabetes mellitus. The aim of this study was to investigate the effect of…”
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Development of Methodology for Identification of Captopril in Medicines by Logoyda Liliya

“…Aim: The aim of the study was to development of a thin layer chromatography (TLC) method for the estimation of captopril. The pharmaceutical industry is under…”
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Conjunction of mitochondrial targeting nutrients for the management of heart dysfunctions associated with type 2 diabetes by Kuchmerovska, Tamara, Sergiichuk, Iuliia, Guzyk, Mykhailo, Dyakun, Kateryna, Tychonenko, Tetyana, Yanitska, Lesya

“…Backgrounds and aims The heart is known to be susceptible to oxidative damage from high ambient oxidant levels, hypercoagulation and hypofibrinolysis…”
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1-Methylnicotinamide (MNA) in prevention of diabetes-associated brain disorders by Kuchmerovska, Tamara, Shymanskyy, Ihor, Chlopicki, Stefan, Klimenko, Arkady

“…The present study has been designed to establish the potential benefits from 1-methylnicotinamide (MNA) treatment on brain disorders associated with type 1…”
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Effects of nicotinamide supplementation on liver and serum contents of amino acids in diabetic rats by Kuchmerovska, Tamara, Shymanskyy, I, Bondarenko, L, Klimenko, A

“…Diabetes-related metabolic impairments may be associated with altered protein and amino acid turnover. The goal of the current research was to estimate…”
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Poly(ADP-ribosyl)ation enhancement in brain cell nuclei is associated with diabetic neuropathy by Kuchmerovska, Tamara, Shymanskyy, Ihor, Donchenko, Georgiy, Kuchmerovskyy, Mykola, Pakirbaieva, Larysa, Klimenko, Arkadiy

“…The study has been undertaken to evaluate the effect of streptozotocin (STZ)-induced diabetes on rat brain poly(ADP-ribose)polymerase (Parp) activity and…”
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