Search Results - "Kucheryavykh, Yuriy V"

Microglia Activate Migration of Glioma Cells through a Pyk2 Intracellular Pathway by Rolón-Reyes, Kimberleve, Kucheryavykh, Yuriy V, Cubano, Luis A, Inyushin, Mikhail, Skatchkov, Serguei N, Eaton, Misty J, Harrison, Jeffrey K, Kucheryavykh, Lilia Y

“…Glioblastoma is one of the most aggressive and fatal brain cancers due to the highly invasive nature of glioma cells. Microglia infiltrate most glioma tumors…”
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Accumulation of Innate Amyloid Beta Peptide in Glioblastoma Tumors by Kucheryavykh, Lilia Y, Ortiz-Rivera, Jescelica, Kucheryavykh, Yuriy V, Zayas-Santiago, Astrid, Diaz-Garcia, Amanda, Inyushin, Mikhail Y

“…Immunostaining with specific antibodies has shown that innate amyloid beta (Aβ) is accumulated naturally in glioma tumors and nearby blood vessels in a mouse…”
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Amyloid Beta Peptide Is Released during Thrombosis in the Skin by Kucheryavykh, Lilia Y, Kucheryavykh, Yuriy V, Washington, A Valance, Inyushin, Mikhail Y

“…While it is known that amyloid beta (Aβ) deposits are found in different tissues of both Alzheimer’s disease (AD) patients and healthy individuals, there…”
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Potassium channel activity and glutamate uptake are impaired in astrocytes of seizure‐susceptible DBA/2 mice by Inyushin, Mikhail, Kucheryavykh, Lilia Y., Kucheryavykh, Yuriy V., Nichols, Colin G., Buono, Russell J., Ferraro, Thomas N., Skatchkov, Serguei N., Eaton, Misty J.

“…Summary Purpose:  KCNJ10 encodes subunits of inward rectifying potassium (Kir) channel Kir4.1 found predominantly in glial cells within the brain. Genetic…”
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Novel KCNJ10 Gene Variations Compromise Function of Inwardly Rectifying Potassium Channel 4.1 by Méndez-González, Miguel P., Kucheryavykh, Yuriy V., Zayas-Santiago, Astrid, Vélez-Carrasco, Wanda, Maldonado-Martínez, Gerónimo, Cubano, Luis A., Nichols, Colin G., Skatchkov, Serguei N., Eaton, Misty J.

“…The KCNJ10 gene encoding Kir4.1 contains numerous SNPs whose molecular effects remain unknown. We investigated the functional consequences of uncharacterized…”
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Targeted Delivery of Nanoparticulate Cytochrome C into Glioma Cells Through the Proton-Coupled Folate Transporter by Kucheryavykh, Yuriy V, Davila, Josue, Ortiz-Rivera, Jescelica, Inyushin, Mikhael, Almodovar, Luis, Mayol, Miguel, Morales-Cruz, Moraima, Cruz-Montañez, Alejandra, Barcelo-Bovea, Vanessa, Griebenow, Kai, Kucheryavykh, Lilia Y

“…In this study, we identified the proton-coupled folate transporter (PCFT) as a route for targeted delivery of drugs to some gliomas. Using the techniques of…”
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Visualization of implanted GL261 glioma cells in living mouse brain slices using fluorescent 4-(4-(dimethylamino)-styryl)-N-methylpyridinium iodide (ASP+) by Kucheryavykh, Lilia Y, Kucheryavykh, Yuriy V, Rolón-Reyes, Kimberleve, Skatchkov, Serguei N, Eaton, Misty J, Cubano, Luis A, Inyushin, Mikhail

“…Here we describe a new method of glioma cell visualization in living brain slices that can be used for evaluation of tumor size or visualization of internal…”
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Intracellular spermine prevents acid-induced uncoupling of Cx43 gap junction channels by Skatchkov, Serguei N, Bukauskas, Feliksas F, Benedikt, Jan, Inyushin, Mikhail, Kucheryavykh, Yuriy V

“…Polyamines (PAs), such as spermine and spermidine, modulate the activity of numerous receptors and channels in the central nervous system (CNS) and are stored…”
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Polyamines preserve connexin 43-mediated gap junctional communication during intracellular hypercalcemia and acidosis by Kucheryavykh, Lilia Y, Benedikt, Jan, Cubano, Luis A, Skatchkov, Serguei N, Bukauskas, Feliksas F, Kucheryavykh, Yuriy V

“…Changes in the regulation, formation, and gating of connexin-based gap junction channels occur in various disorders. It has been shown that H and Ca are…”
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Intracellular polyamines enhance astrocytic coupling by Benedikt, Jan, Inyushin, Mikhail, Kucheryavykh, Yuriy V, Rivera, Yomarie, Kucheryavykh, Lilia Y, Nichols, Colin G, Eaton, Misty J, Skatchkov, Serguei N

“…Spermine (SPM) and spermidine, endogenous polyamines with the ability to modulate various ion channels and receptors in the brain, exert neuroprotective,…”
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HIV-1 Envelope Protein gp120 Promotes Proliferation and the Activation of Glycolysis in Glioma Cell by Valentín-Guillama, Gabriel, López, Sheila, Kucheryavykh, Yuriy V, Chorna, Nataliya E, Pérez, Jose, Ortiz-Rivera, Jescelica, Inyushin, Michael, Makarov, Vladimir, Valentín-Acevedo, Aníbal, Quinones-Hinojosa, Alfredo, Boukli, Nawal, Kucheryavykh, Lilia Y

“…Patients infected with human immunodeficiency virus (HIV) are more prone to developing cancers, including glioblastomas (GBMs). The median survival for HIV…”
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Complex rectification of Müller cell Kir currents by Kucheryavykh, Yuriy V., Shuba, Yaroslav M., Antonov, Sergei M., Inyushin, Mikhail Y., Cubano, Luis, Pearson, Wade L., Kurata, Harley, Reichenbach, Andreas, Veh, Rüdiger W., Nichols, Colin G., Eaton, Misty J., Skatchkov, Serguei N.

“…Although Kir4.1 channels are the major inwardly rectifying channels in glial cells and are widely accepted to support K+‐ and glutamate‐uptake in the nervous…”
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Ischemia Increases TREK-2 Channel Expression in Astrocytes: Relevance to Glutamate Clearance by Kucheryavykh, Lilia Y, Kucheryavykh, Yuriy V, Inyushin, Mikhail, Shuba, Yaroslav M, Sanabria, Priscila, Cubano, Luis A, Skatchkov, Serguei N, Eaton, Misty J

“…The extent of an ischemic insult is less in brain regions enriched in astrocytes suggesting that astrocytes maintain function and buffer glutamate during…”
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Polyamines preserve connexin43-mediated gap junctional communication during intracellular hypercalcemia and acidosis by Kucheryavykh, Lilia Y., Benedikt, Jan, Cubano, Luis A., Skatchkov, Serguei N., Bukauskas, Feliksas F., Kucheryavykh, Yuriy V.

“…Changes in the regulation, formation, and gating of connexin (Cx)-based gap junction channels occur in various disorders. It has been shown that H + and Ca 2+…”
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Hyperglycemia reduces functional expression of astrocytic Kir4.1 channels and glial glutamate uptake by Rivera-Aponte, D.E, Méndez-González, M.P, Rivera-Pagán, A.F, Kucheryavykh, Y.V, Kucheryavykh, L.Y, Skatchkov, S.N, Eaton, M.J

“…Highlights • The effect of hyperglycemia on astrocytic potassium channel function was studied. • Hyperglycemia decreases astrocytic Kir4.1 mRNA and protein…”
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