Search Results - "Kuc, R."

New drugs and emerging therapeutic targets in the endothelin signaling pathway and prospects for personalized precision medicine by Davenport, A P, Kuc, R E, Southan, C, Maguire, J J

“…During the last thirty years since the discovery of endothelin-1, the therapeutic strategy that has evolved in the clinic, mainly in the treatment of pulmonary…”
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Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system by Mead, E J, Maguire, J J, Kuc, R E, Davenport, A P

“…Orphan G‐protein‐coupled receptors that have recently been paired with their cognate ligand are an often untapped resource for novel drug development. The…”
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Binaural sonar electronic travel aid provides vibrotactile cues for landmark, reflector motion and surface texture classification by Kuc, R.

“…Electronic travel aids (ETAs) for the blind commonly employ conventional time-of-flight sonars to provide range measurements, but their wide beams prevent…”
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Orphan‐receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin‐1 by Maguire, Janet J, Kuc, Rhoda E, Davenport, Anthony P

“…We have determined the distribution of receptors for human urotensin‐II (U‐II) in human and rat CNS and peripheral tissues. In rat, [125I]‐U‐II binding density…”
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Generating B-Scans of the Environment With a Conventional Sonar by Kuc, R.

“…This paper examines the task of displaying more information about the environment using a conventional ranging sonar than is available in standard…”
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Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1 by Kelland, N F, Kuc, R E, McLean, D L, Azfer, A, Bagnall, A J, Gray, G A, Gulliver-Sloan, F H, Maguire, J J, Davenport, A P, Kotelevtsev, Y V, Webb, D J

“…Inactivation of endothelin B receptors (ETB), either through selective pharmacological antagonism or genetic mutation, increases the circulating concentration…”
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Neuromorphic Processing of Moving Sonar Data for Estimating Passing Range by Kuc, R.

“…Ranging sensors typically estimate range in order to register object locations with respect to a floor plan. This paper uses range readings from a moving sonar…”
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Characterization of the snake venom ligand [125I]‐DNP binding to natriuretic peptide receptor‐A in human artery and potent DNP mediated vasodilatation by Singh, G, Maguire, J J, Kuc, R E, Skepper, J N, Fidock, M, Davenport, A P

“…Background and purpose: The natriuretic peptides, ANP and BNP, modulate vascular smooth muscle tone in human conduit arteries. Surprisingly, the natriuretic…”
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Transforming echoes into pseudo-action potentials for classifying plants by Kuc, R

“…Animals perceive their environment by converting sensory stimuli into action potentials, or temporal point processes, that are interpreted by the brain. This…”
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Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system by Katugampola, S D, Maguire, J J, Kuc, R E, Wiley, K E, Davenport, A P

“…Using novel synthetic radioligands, we have discovered receptors for the recently paired apelin (APJ orphan receptor), ghrelin (GHS orphan receptor), and…”
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Teaching the nonscience major: EE101-The digital information age by Kuc, R.

“…EE 10l-The Digital Information Age, a course taught for the past six years to nonscience majors and freshmen considering electrical engineering as a major, is…”
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High-resolution adaptive spiking sonar by Alvarez, F.J., Kuc, R.

“…A new sonar system based on the conventional 6500 ranging module is presented that generates a sequence of spikes whose temporal density is related to the…”
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Characterization and Localization of Endothelin Receptor Subtypes in the Human Atrioventricular Conducting System and Myocardium by Molenaar, Peter, OʼReilly, Gillian, Sharkey, Andrew, Kuc, Rhoda E, Harding, Deborah P, Plumpton, Christopher, Gresham, G Austin, Davenport, Anthony P

“…The characterization and localization of endothelin A (ETA) and endothelin B (ETB) receptors have been determined in tissue sections of the human…”
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Improving object classification with biomimetic sonar by Kuc, R

“…This paper presents improvements to a previously described biomimetic system to make it more robust in terms of localizing objects and increasing the types of…”
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Endothelin ETA and ETB mRNA and receptors expressed by smooth muscle in the human vasculature: majority of the ETA sub‐type by Davenport, Anthony P., O'Reilly, Gillian, Kuc, Rhoda E.

“…1 We measured the ratio of ETA and ETB sub‐types in the media (containing mainly smooth muscle) of human cardiac arteries (aorta, pulmonary and coronary),…”
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Vasoconstrictor activity of novel endothelin peptide, ET‐1(1 – 31), in human mammary and coronary arteries in vitro by Maguire, Janet J, Kuc, Rhoda E, Davenport, Anthony P

“…The ability of the putative chymase product of big endothelin‐1 (big ET‐1), ET‐1(1 – 31), to constrict isolated endothelium‐denuded preparations of human…”
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Differentiating sonar reflections from corners and planes by employing an intelligent sensor by Barshan, B., Kuc, R.

“…A multitransducer, pulse/echo-ranging system is described that differentiates corner and plane reflectors by exploiting the physical properties of sound…”
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Biomimetic sonar locates and recognizes objects by Kuc, R.

“…An active sonar is described that adaptively changes its location and configuration in response to the echoes it observes in order to locate an object,…”
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Maternal Dexamethasone Increases Endothelin-1 Sensitivity and Endothelin A Receptor Expression in Ovine Foetal Placental Arteries by Kutzler, M.A, Molnar, J, Schlafer, D.H, Kuc, R.E, Davenport, A.P, Nathanielsz, P.W

“…Despite National Institutes of Health recommendations to administer antenatal steroids as a single course to women threatening preterm delivery, repeated…”
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Transmyocardial extraction of endothelin-1 correlates with increased microvascular resistance following percutaneous coronary intervention by Abraham, G R, Nyimanu, D, Kuc, R, Maguire, J, Davenport, A P, Hoole, S P

“…Abstract Introduction Coronary microvascular dysfunction (CMD) can persist following successful percutaneous coronary intervention (PCI). Endothelin-1 (ET-1)…”
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