Search Results - "Kubova, H."

Are morphologic and functional consequences of status epilepticus in infant rats progressive? by KUBOVA, H, MARES, P

“…Highlights ► Risk of epilepsy increases with interval after early-life status epilepticus. ► Age at status epilepticus is decisive for semiology of spontaneous…”
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Chemobrain in blood cancers: How chemotherapeutics interfere with the brain's structure and functionality, immune system, and metabolic functions by Skurlova, M., Holubova, K., Kleteckova, L., Kozak, T., Kubova, H., Horacek, J., Vales, K.

“…Cancer treatment brings about a phenomenon not fully clarified yet, termed chemobrain. Its strong negative impact on patients' well‐being makes it a trending…”
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Influence of early life status epilepticus on the developmental expression profile of the GluA2 subunit of AMPA receptors by Szczurowska, E., Ergang, P., Kubová, H., Druga, R., Salaj, M., Mareš, P.

“…AMPA receptors (AMPARs) are responsible for fast excitatory neurotransmission, and their prolonged activation can result in the generation and spread of…”
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Do Stereoisomers of Homocysteic Acid Exhibit Different Convulsant Action in Immature Rats? by MAREŠ, P., FOLBERGROVÁ, J., HAUGVICOVÁ, R., KUBOVÁ, H.

“…Mechanism of ictogenesis of D- and L-stereroisomers of homocysteic acid was studied in 12-day-old rats by means of antagonists of N-methyl-D-aspartate (NMDA)…”
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Hyperthermia aggravates status epilepticus-induced epileptogenesis and neuronal loss in immature rats by Suchomelova, L, Lopez-Meraz, M.L, Niquet, J, Kubova, H, Wasterlain, C.G

“…Highlights • Status epilepticus (SE) in hyperthermic and normothermic animals was similar. • Hyperthermia plus seizure induced neuronal injury in the amygdala…”
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Ontogenetic development of sensitivity of the cerebral cortex to an antagonist of GABA(A) receptor bicuculline by Mareš, P, Bernášková, K, Kubová, H

“…Local application of four concentrations of bicuculline methiodide (a specific antagonist of GABA(A) receptors) was used to study a sensitivity of…”
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Rebound increase in seizure susceptibility but not isolation-induced calls after single administration of clonazepam and Ro 19-8022 in infant rats by Mikulecka, A, Mares, P, Kubova, H

“…Abstract The purpose of our study was to determine whether a single administration of anticonvulsant doses of two ligands of benzodiazepine receptors,…”
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LYMPHOMA TREATMENT REGIMES AND THEIR IMPACT ON BEHAVIOUR AND COGNITION IN AN ANIMAL MODEL by Vales, K., Skurlova, M., Holubova, K., Kleteckova, L., Mikulecka, A., Kozak, T., Kubova, H., Horacek, J.

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Partial Agonist of Benzodiazepine Receptors Ro 19-2088 Elicits Withdrawal Symptoms After Short-Term Administration in Immature Rats by KUBOVÁ, H., MAREŠ, P.

“…Repeated administration of partial agonist of benzodiazepine receptors Ro 19-8022 (a derivative of quinolizine class) does not elicit withdrawal in adult rats…”
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Anticonvulsant action of a new analogue of allopregnanolone in immature rats by Mares, P, Kubová, H, Kasal, A

“…Neuroactive steroids represent potential antiepileptic drugs. We tested a newly synthesized analogue of allopregnanolone…”
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What is the role of neurotransmitter systems in cortical seizures? by Mares, P, Kubová, H

“…Epileptic afterdischarges (ADs) elicited by electrical stimulation of sensorimotor cortical area were used as a model to study the role of neurotransmitter…”
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Transient changes of cortical interhemispheric responses after repeated caffeine administration in immature rats by Tchekalarova, J, Kubová, H, Mareš, P

“…Repeated postnatal caffeine treatment of rat pups led to transient developmental changes in cortical epileptic afterdischarges. To know if physiological…”
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Effect of endothelin-1 on the excitability of rat cortical and hippocampal slices in vitro by Konopková, R, Vilagi, I, Borbely, S, Kubová, H, Otáhal, J

“…Endothelin-1 (ET-1) is a neuroactive protein produced in most brain cell types and participates in regulation of cerebral blood flow and blood pressure. In…”
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Seizures induced by homocysteine in rats during ontogenesis by Kubová, H, Folbergrová, J, Mares, P

“…We studied the convulsant action of homocysteine in 211 immature and adult Wistar albino rats. Homocysteine elicited minimal, predominantly clonic, and major…”
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Selection of Antiepileptic Drug Polytherapy Based on Mechanisms of Action: The Evidence Reviewed by Deckers, Charles L. P., Czuczwar, Stanislaw J., Hekster, Yechiel A., Kewser, Antoine, Kubova, Hana, Meinardi, Harry, Patsalos, Philip N., Renier, Willy O., Rijn, Clementina M.

“…Purpose: When monotherapy with antiepileptic drugs (AEDs) fails, combination therapy is tried in an attempt to improve effectiveness by improving efficacy,…”
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An antagonist of GABA-B receptors potentiates activity of cortical epileptic foci by Mares, P, Bernásková, K, Kubová, H

“…Cortical epileptic foci elicited by local application of bicuculline methiodide represent a model of interictal epileptic activity with a transition into ictal…”
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Convulsant Action of D,L‐Homocysteic Acid and Its Stereoisomers in Immature Rats by Mareš, Pave1, Folbergrová, J., Langmeier, M., Haugvicová, R., Kubová, H.

“…Purpose: We wished to characterize the convulsant effect of homocysteic acid (HCA) in developing rats. Methods: Seizures were induced in 7‐, 12‐, 18‐, and…”
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Anticonvulsant action of oxcarbazepine, hydroxycarbamazepine, and carbamazepine against metrazol-induced motor seizures in developing rats by Kubová, H, Mares, P

“…Antimetrazol effects of carbamazepine (CBZ, 5, 12.5, 25, or 50 mg/kg), oxcarbazepine (OCBZ, 5, 10, 30, or 60 mg/kg), and hydroxycarbamazepine (HCBZ, the main…”
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Ontogenetic Development of Sensitivity of the Cerebral Cortex to an Antagonist of GABAA Receptor Bicuculline by MAREŠ, P., BERNÁŠKOVÁ, K., KUBOVÁ, H.

“…Local application of four concentrations of bicuculline methiodide (a specific antagonist of GABAA receptors) was used to study a sensitivity of somatosensory…”
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Two Different Anticonvulsant Actions of Tiagabine in Developing Rats by HAUGVICOVA, R, SKUTOVA, M, KUBOVA, H, SUCHOMELOVA, L, MARES, P

“…Purpose: Our goal was to study the anticonvulsant action of tiagabine (TGB) at different levels of brain maturation in rats. Methods: Wistar rats in five age…”
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