Search Results - "Kuboniwa, Hitoshi"
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Solution structure of the DNA binding domain of a nucleoid-associated protein, H-NS, from Escherichia coli
Published in FEBS letters (27-02-1995)“…The three-dimensional structure of the C-terminal domain (47 residues) obtained from the hydrolysis of H-NS protein with bovine trypsin was determined by NMR…”
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The stability and degradation pathway of recombinant human parathyroid hormone : Deamidation of asparaginyl residue and peptide bond cleavage at aspartyl and asparaginyl residues
Published in Pharmaceutical research (01-12-1997)“…The stability of recombinant human parathyroid hormone (rhPTH) was examined under acidic to alkaline conditions; its degradation pathways were elucidated from…”
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Measurement of HN-H? J couplings in calcium-free calmodulin using new 2D and 3D water-flip-back methods
Published in Journal of biomolecular NMR (01-11-1994)Get full text
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Multiple-Quantum Line Narrowing for Measurement of H.alpha.-H.beta. J Couplings in Isotopically Enriched Proteins
Published in Journal of the American Chemical Society (01-05-1995)Get full text
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Polypeptide and carbohydrate structure of recombinant human interleukin-6 produced in Chinese hamster ovary cells
Published in Journal of biochemistry (Tokyo) (01-02-1994)“…A glycosylated form of human interleukin 6 (hIL-6) has been produced in Chinese hamster ovary (CHO) cells transfected with a cDNA clone for human IL-6…”
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Solution structure of calcium-free calmodulin
Published in Nature structural biology (01-09-1995)“…The three-dimensional structure of calmodulin in the absence of Ca2+ has been determined by three- and four-dimensional heteronuclear NMR experiments,…”
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Impact of Different Elastomer Formulations on Moisture Permeation through Stoppers Used for Lyophilized Products Stored under Humid Conditions
Published in PDA journal of pharmaceutical science and technology (01-01-2010)“…The purpose of this study was to evaluate the effect of moisture permeability of different elastomer formulation stoppers, which had different moisture…”
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Rotational dynamics of calcium-free calmodulin studied by 15N-NMR relaxation measurements
Published in European journal of biochemistry (15-06-1995)“…The backbone motions of calcium-free Xenopus calmodulin have been characterized by measurements of the 15N longitudinal relaxation times (T1) at 51 and 61 MHz,…”
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GM-611, a novel erythromycin derivative, acts as a motilin agonist in the rabbit duodenum
Published in Japanese Journal of Pharmacology (1994)“…It is known that erythromycin (EMA), a macrolide antibiotic, is a motilin agonist and that EM-523, one of the derivatives of EMA, is being developed as a…”
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O-linked sugar chain of human granulocyte colony-stimulating factor protects it against polymerization and denaturation allowing it to retain its biological activity
Published in The Journal of biological chemistry (15-07-1990)“…Human granulocyte colony-stimulating factor (hG-CSF) is a glycoprotein carrying one O-linked sugar chain. To clarify the role of the oligosaccharide in hG-CSF,…”
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Oxidation of recombinant human parathyroid hormone : effect of oxidized position on the biological activity
Published in Pharmaceutical research (01-12-1995)“…To determine the oxidation products of recombinant human parathyroid hormone (rhPTH) treated with H2O2, the amino acid residue oxidized, and the biological…”
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Kinetic study of methionine oxidation in human parathyroid hormone
Published in Analytica chimica acta (05-06-1998)“…Human parathyroid hormone (hPTH) has two methionine (Met) residues at positions 8 and 18. These are oxidized to Met sulfoxide in the presence of an oxidant…”
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Journal Article Conference Proceeding -
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Studies on Plastic Container for Aqueous Infusion
Published in YAKUGAKU ZASSHI (25-05-1984)“…In order to develop the aqueous infusion packed in a polypropylene (PP) container, the properties of the PP containers, packed with distilled water and a…”
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Peptide mapping of recombinant human parathyroid hormone by enzymatic digestion and subsequent fast-atom bombardment mass spectrometry
Published in Rapid communications in mass spectrometry (1995)“…Peptide maps of recombinant human parathyroid hormone (rhPTH) were determined by both trypsin and V-8 protease digestion with subsequent fast-atom bombardment…”
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Rotational Dynamics of Calcium‐Free Calmodulin Studied by 15 N‐NMR Relaxation Measurements
Published in European journal of biochemistry (01-06-1995)“…The backbone motions of calcium‐free Xenopus calmodulin have been characterized by measurements of the 15 N longitudinal relaxation times ( T 1 ) at 51 and 61…”
Get full text
Journal Article -
18
Rotational Dynamics of Calcium‐Free Calmodulin Studied by 15N‐NMR Relaxation Measurements
Published in European journal of biochemistry (01-06-1995)“…The backbone motions of calcium‐free Xenopus calmodulin have been characterized by measurements of the 15N longitudinal relaxation times (T1) at 51 and 61 MHz,…”
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Journal Article -
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Studies on Plastic Container for Aqueous Infusion
Published in Yakugaku zasshi (1984)Get full text
Journal Article -
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P-371 - GM-611, a novel erythromycin derivative, acts as a motilin agonist in the rabbit duodenum
Published in Japanese journal of pharmacology (1994)Get full text
Journal Article