Search Results - "Kubofcik, Joseph"
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Zoonotic Ancylostoma ceylanicum Hookworm Infections, Ecuador
Published in Emerging infectious diseases (01-09-2022)“…Ancylostoma ceylanicum hookworms are zoonotic parasites that can infect humans. To detect autochthonous transmission, we analyzed human fecal samples collected…”
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Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels
Published in PLoS neglected tropical diseases (19-05-2017)“…Serological antibody levels are a sensitive marker of pathogen exposure, and advances in multiplex assays have created enormous potential for large-scale,…”
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Extended result reading window in lateral flow tests detecting exposure to Onchocerca volvulus: a new technology to improve epidemiological surveillance tools
Published in PloS one (23-07-2013)“…Onchocerciasis is a neglected tropical disease caused by infection with the parasite Onchocerca volvulus (Ov). An estimated 180 million people are at risk for…”
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Isolation of Onchocerca lupi in Dogs and Black Flies, California, USA
Published in Emerging infectious diseases (01-05-2015)“…In southern California, ocular infections caused by Onchocerca lupi were diagnosed in 3 dogs (1 in 2006, 2 in 2012). The infectious agent was confirmed through…”
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Identification of Wb123 as an early and specific marker of Wuchereria bancrofti infection
Published in PLoS neglected tropical diseases (01-12-2012)“…The current antibody tests used for monitoring in lymphatic filariasis (LF) elimination programs suffer from poor specificity because of the considerable…”
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Comparison of antigen and antibody responses in repeat lymphatic filariasis transmission assessment surveys in American Samoa
Published in PLoS neglected tropical diseases (09-03-2018)“…Current WHO recommendations for lymphatic filariasis (LF) surveillance advise programs to implement activities to monitor for new foci of transmission after…”
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Rapid Wuchereria bancrofti-Specific Antigen Wb123-Based IgG4 Immunoassays as Tools for Surveillance following Mass Drug Administration Programs on Lymphatic Filariasis
Published in Clinical and Vaccine Immunology (01-08-2013)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Comparison of three immunoassays for detection of antibodies to Strongyloides stercoralis
Published in Clinical and vaccine immunology (01-05-2014)“…Due to the limited sensitivities of stool-based microscopy and/or culture techniques for Strongyloides stercoralis, the detection of antibodies to this…”
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Longitudinal monitoring of the development of antifilarial antibodies and acquisition of Wuchereria bancrofti in a highly endemic area of Haiti
Published in PLoS neglected tropical diseases (01-12-2012)“…Antifilarial antibody testing has been established as a sensitive and specific method of diagnosing lymphatic filariasis. However, the development of…”
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Antibody to the filarial antigen Wb123 reflects reduced transmission and decreased exposure in children born following single mass drug administration (MDA)
Published in PLoS neglected tropical diseases (01-12-2012)“…Antibody (Ab) to the Wuchereria bancrofti (Wb) infective larval (L3) antigen Wb123, using a Luciferase Immunoprecipitation System (LIPS) assay, has been shown…”
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Parasite Antigen-Driven Basophils Are a Major Source of IL-4 in Human Filarial Infections
Published in The Journal of immunology (1950) (15-02-2004)“…Basophil contribution to the IL-4 pool in filarial infections was assessed using PBMC from 20 patients with active filarial infections and from 9 uninfected…”
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Filaria-Induced Immune Evasion: Suppression by the Infective Stage of Brugia malayi at the Earliest Host-Parasite Interface
Published in The Journal of immunology (1950) (15-05-2004)“…To assess the physiologic interactions between the infective stage of Brugia malayi--one of the extracellular parasites responsible for lymphatic filariasis in…”
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Filaria-Induced Monocyte Dysfunction and Its Reversal following Treatment
Published in Infection and Immunity (01-08-2006)“…Monocyte dysfunction in filarial infection has been proposed as one mechanism underlying the diminished antigen-specific T-cell response seen in patent…”
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Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus
Published in Science translational medicine (15-02-2017)“…Nodding syndrome is an epileptic disorder of unknown etiology that occurs in children in East Africa. There is an epidemiological association with , the…”
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Differences in the Clinical and Laboratory Features of Imported Onchocerciasis in Endemic Individuals and Temporary Residents
Published in The American journal of tropical medicine and hygiene (01-05-2019)“…Many parasitic infections have different presenting features in endemic individuals (ENDs) and immunologically naive temporary residents (TRs). Temporary…”
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Loa loa Microfilariae in Skin Snips: Consequences for Onchocerciasis Monitoring and Evaluation in L. loa–Endemic Areas
Published in Clinical infectious diseases (15-10-2019)“…Abstract The specificity of skin snips for onchocerciasis diagnoses is considered to be almost 100%. Our molecular methods revealed that microfilariae emerging…”
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Doxycycline for the treatment of nodding syndrome: a randomised, placebo-controlled, phase 2 trial
Published in The Lancet global health (01-07-2024)“…Nodding syndrome is a poorly understood neurological disorder that predominantly occurs in Africa. We hypothesised that nodding syndrome is a neuroinflammatory…”
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Molecular Epidemiology of Blood-Borne Human Parasites in a Loa loa-, Mansonella perstans-, and Plasmodium falciparum-Endemic Region of Cameroon
Published in The American journal of tropical medicine and hygiene (01-06-2016)“…The study of the interactions among parasites within their hosts is crucial to the understanding of epidemiology of disease and for the design of effective…”
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A Serological Survey of Human Onchocerciasis in Yemen
Published in The American journal of tropical medicine and hygiene (01-01-2018)“…Yemen is a country that has been treating severe cases of oncho-dermatitis since 1992 and is now moving to a program aimed at the elimination of the…”
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Comparison of Structural Changes in Nodding Syndrome and Other Epilepsies Associated With Onchocerca volvulus
Published in Neurology : neuroimmunology & neuroinflammation (01-03-2023)“…Nodding syndrome (NS) is a unique childhood-onset epileptic disorder that occurs predominantly in several regions of sub-Saharan Africa. The disease has been…”
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