Search Results - "Kubo, Isao"

Effects of Thymol on Mushroom Tyrosinase-Catalyzed Melanin Formation by Satooka, Hiroki, Kubo, Isao

“…The novel inhibitory mechanism of thymol (2-isopropyl-5-methylphenol) on dopachrome formation by mushroom tyrosinase (EC 1.14.18.1) was identified. The UV–vis…”
Get full text

Tyrosinase Inhibition by 4-Substituted Benzaldehydes with Electron-Withdrawing Groups by Nihei, Ken-ichi, Kubo, Isao

“…The oxidation of 4- t -butylcatechol catalyzed by mushroom tyrosinase was inhibited by 4-bromobenzaldehyde, 4-chlorobenzaldehyde, 4-fluorobenzaldehyde,…”
Get full text

Substituent effect of benzaldehydes on tyrosinase inhibition by Nihei, Ken-ichi, Kubo, Isao

“…Benzaldehyde inhibited the oxidation of 4-t-butylcatechol catalyzed by mushroom tyrosinase with an IC50 of 31.0 μM. The inhibition kinetics analyzed by Dixon…”
Get full text

Anti-Salmonella Activity of Volatile Compounds of Vietnam Coriander by Fujita, Ken-ichi, Chavasiri, Warinthorn, Kubo, Isao

“…Essential oil derived from the fresh leaves of Polygonum odoratum Lour was tested for their effects on a foodborne bacterium Salmonella choleraesuis subsp…”
Get full text

Anethole induces apoptotic cell death accompanied by reactive oxygen species production and DNA fragmentation in Aspergillus fumigatus and Saccharomyces cerevisiae by Fujita, Ken‐Ichi, Tatsumi, Miki, Ogita, Akira, Kubo, Isao, Tanaka, Toshio

“…trans‐Anethole (anethole), a major component of anise oil, has a broad antimicrobial spectrum, and antimicrobial activity that is weaker than that of other…”
Get full text

Kinetics of Mushroom Tyrosinase Inhibition by Quercetin by Chen, Qing-Xi, Kubo, Isao

“…The effects of quercetin on the activity of mushroom tyrosinase were studied. The equilibrium constants for this inhibitor binding with the enzyme molecule…”
Get full text

Tyrosinase Inhibitors from Calceolaria integrifolia s.l.: Calceolaria talcana Aerial Parts by Muñoz, Evelyn, Avila, Jose G, Alarcón, Julio, Kubo, Isao, Werner, Enrique, Céspedes, Carlos L

“…As a defense mechanism of the aerial parts of Calceolaria talcana (Calceolariaceae; formerly Scrophulariaceae) against herbivore offenses and insect pest…”
Get full text

Antibacterial Activity of Coriander Volatile Compounds against Salmonella choleraesuis by Kubo, Isao, Fujita, Ken-ichi, Kubo, Aya, Nihei, Ken-ichi, Ogura, Tetsuya

“…Aliphatic (2E)-alkenals and alkanals characterized from the fresh leaves of the coriander Coriandrum sativum L. (Umbelliferae) were found to possess…”
Get full text

Resveratrol as a kcat type inhibitor for tyrosinase: Potentiated melanogenesis inhibitor by Satooka, Hiroki, Kubo, Isao

“…Resveratrol exhibited the inhibitory activity against mushroom tyrosinase (EC1.14.18.1) through a kcat inhibition. Resveratrol itself did not inhibit…”
Get full text

Characterization of xanthine oxidase inhibition by anacardic acids by Masuoka, Noriyoshi, Kubo, Isao

“…Anacardic acid, 6[8(Z), 11(Z), 14-pentadecatrienyl]salicylic acid, inhibits generation of superoxide radicals by xanthine oxidase. This inhibition does not…”
Get full text

Multifunctional cytotoxic agents from Anacardium occidentale by Kubo, Isao, Nitoda, Teruhiko, Tocoli, Felismino E., Green, Ivan R.

“…The effects of anacardic acids and cardols isolated from the cashew nut and apple Anacardium occidentale (Anacardiaceae) on murine B16‐F10 melanoma cells were…”
Get full text

Effects of quercetin on mushroom tyrosinase and B16-F10 melanoma cells by Kubo, Isao, Nitoda, Teruhiko, Nihei, Ken-ichi

“…In searching for tyrosinase inhibitors from plants using L-3,4-dihydroxyphenylalanine (L-DOPA) as a substrate, quercetin was found to be partially oxidized to…”
Get full text

Superoxide anion scavenging activity of alk(en)yl phenol compounds by using PMS-NADH system by Masuoka, Noriyoshi, Tamsampaoloet, Kulwadee, Chavasiri, Warinthorn, Kubo, Isao

“…Anacardic acid C15:3 and cardol C15:3 sigmoidally suppressed superoxide anion (O2-) generation using xanthine oxidase. To study this suppression activity,…”
Get full text

Flavonols from Saffron Flower:  Tyrosinase Inhibitory Activity and Inhibition Mechanism by Kubo, Isao, Kinst-Hori, Ikuyo

“…A common flavonol, kaempferol, isolated from the fresh flower petals of Crocus sativus L. (Iridaceae) was found to inhibit the oxidation of…”
Get full text

Construction of bacteria–eukaryote synthetic mutualism by Kubo, Isao, Hosoda, Kazufumi, Suzuki, Shingo, Yamamoto, Kayo, Kihara, Kumiko, Mori, Kotaro, Yomo, Tetsuya

“…Mutualism is ubiquitous in nature but is known to be intrinsically vulnerable with regard to both population dynamics and evolution. Synthetic ecology has…”
Get full text

Stereochemical investigation and total synthesis of inuloidin, a biologically active sesquiterpenoid from Heterotheca inuloides by Kamatani, Jumpei, Iwadate, Takehiro, Tajima, Reiko, Kimoto, Hideaki, Yamada, Yoichi, Masuoka, Noriyoshi, Kubo, Isao, Nihei, Ken-ichi

“…The stereochemistry of inuloidin (1), which was a sesquiterpenoid that was characterized as a plant growth inhibitory substance from Heterotheca inuloides, was…”
Get full text

Oxidation products of quercetin catalyzed by mushroom tyrosinase by Kubo, Isao, Nihei, Ken-ichi, Shimizu, Kuniyoshi

“…Quercetin was oxidized as a substrate catalyzed by mushroom tyrosinase to the corresponding o-quinone and subsequent isomerization to p-quinone methide type…”
Get full text

Morphological Changes of the Filamentous Fungus Mucor Mucedo and Inhibition of Chitin Synthase Activity Induced by Anethole by Yutani, Masahiro, Hashimoto, Yukie, Ogita, Akira, Kubo, Isao, Tanaka, Toshio, Fujita, Ken-ichi

“…trans‐Anethole (anethole), a major component of anise oil, has a broad antimicrobial spectrum with antimicrobial activity relatively weaker than those of…”
Get full text

Molecular design of antibrowning agents: antioxidative tyrosinase inhibitors by Kubo, Isao, Chen, Qing-Xi, Nihei, Ken-ichi

“…Dodecyl (C 12) gallate (3,4,5-trihydroxybenzoate) was found to inhibit the oxidation of l-3,4-dihydroxyphenylalanine ( l-DOPA) catalyzed by tyrosinase. This…”
Get full text

Antimicrobial activity of anethole and related compounds from aniseed by Kubo, Isao, Fujita, Ken-ichi, Nihei, Ken-ichi

“…The antimicrobial activities of anethole, anisic acid, and eugenol characterized from aniseed were tested against 18 organisms including both bacteria and…”
Get full text