Search Results - "Kubitza, Marion"
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Hepatic Amyloid Beta-42-Metabolizing Proteins in Liver Steatosis and Metabolic Dysfunction-Associated Steatohepatitis
Published in International journal of molecular sciences (12-08-2024)“…Amyloid beta (Aβ) plays a major role in the pathogenesis of Alzheimer's disease and, more recently, has been shown to protect against liver fibrosis…”
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Saturated Fat-Mediated Upregulation of IL-32 and CCL20 in Hepatocytes Contributes to Higher Expression of These Fibrosis-Driving Molecules in MASLD
Published in International journal of molecular sciences (25-08-2023)“…Metabolic dysfunction-associated steatotic liver disease (MASLD) comprises a spectrum of liver diseases, ranging from liver steatosis to metabolic…”
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Interleukin-1ß Attenuates Expression of Augmenter of Liver Regeneration (ALR) by Regulating HNF4α Independent of c-Jun
Published in International journal of molecular sciences (30-04-2023)“…Inflammasomes and innate immune cells have been shown to contribute to liver injury, thereby activating Kupffer cells, which release several cytokines,…”
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LMX1B is Essential for the Maintenance of Differentiated Podocytes in Adult Kidneys
Published in Journal of the American Society of Nephrology (01-11-2013)“…Mutations of the LMX1B gene cause nail-patella syndrome, a rare autosomal-dominant disorder affecting the development of the limbs, eyes, brain, and kidneys…”
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PV-1 Is a Component of the Fenestral and Stomatal Diaphragms in Fenestrated Endothelia
Published in Proceedings of the National Academy of Sciences - PNAS (09-11-1999)“…PV-1 is a novel endothelial protein shown by immunocytochemical tests to be specifically associated with the stomatal diaphragms of caveolae in lung…”
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Expression of pigment-epithelium-derived factor during kidney development and aging
Published in Cell and tissue research (01-08-2007)“…Inhibitors and stimulators of endothelial cell growth are essential for the coordination of blood vessel formation during organ growth and development. In the…”
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A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts
Published in Journal of cell science (15-08-2021)“…Mutations in the PKD2 gene cause autosomal-dominant polycystic kidney disease but the physiological role of polycystin-2, the protein product of PKD2, remains…”
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The LIM‐homeodomain transcription factor LMX1B supports the maintenance of differentiated podocytes by modulating the actin cytoskeleton
Published in The FASEB journal (01-04-2011)“…Mutations in the LMX1B gene cause a rare autosomal‐dominant disorder affecting the development of the limbs, eyes, brain and kidneys, called nail‐patella…”
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ICAM-1 and VCAM-1 expression following aneurysmal subarachnoid hemorrhage and their possible role in the pathophysiology of subsequent ischemic deficits
Published in Cerebrovascular diseases (Basel, Switzerland) (01-07-2006)“…The pathophysiology of ischemic cerebral lesions following aneurysmal subarachnoid hemorrhage (SAH) is poorly understood. There is growing evidence that…”
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Expression of hypoxia-inducible carbonic anhydrases in brain tumors
Published in Neuro-oncology (Charlottesville, Va.) (01-10-2005)“…Malignant brain tumors exhibit distinct metabolic characteristics. Despite high levels of lactate, the intracellular pH of brain tumors is more alkaline than…”
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Doxycycline accelerates renal cyst growth and fibrosis in the pcy/pcy mouse model of type 3 nephronophthisis, a form of recessive polycystic kidney disease
Published in Histochemistry and cell biology (01-08-2009)“…Nephronophthisis belongs to a family of recessive cystic kidney diseases and may arise from mutations in multiple genes. In this report we have used a…”
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Tonic neurogenic inhibition of interleukin-6 secretion from murine spleen caused by opioidergic transmission
Published in The American journal of physiology (01-04-1998)“…The peripheral nervous system and the immune system were shown to have neurohumoral interactions. This study extends observations that demonstrated neuronal…”
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Influence of host microvascular environment on tumour vascular endothelium
Published in International journal of experimental pathology (01-01-1999)“…This review will focus on the tumour microvascular endothelium; how it is derived, modulated by angiogenic factors, and how the structure and function is…”
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Aldosterone modulates PNA binding cell isoforms within renal collecting duct epithelium
Published in Kidney international (01-09-1993)“…Aldosterone modulates PNA binding cell isoforms within renal collecting duct epithelium. To investigate the differentiation of the ampullary collecting duct…”
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