Search Results - "Kubbinga, Marlies"

The Influence of Chitosan on the Oral Bioavailability of Acyclovir—a Comparative Bioavailability Study in Humans by Kubbinga, Marlies, Nguyen, Mai Anh, Staubach, Petra, Teerenstra, Steven, Langguth, Peter

“…ABSTRACT Purpose The effects of chitosan hydrochloride on the oral absorption of acyclovir in humans were studied to confirm the absorption enhancing effects…”
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The effect of chitosan on the bioaccessibility and intestinal permeability of acyclovir by Kubbinga, Marlies, Augustijns, Patrick, García, Mauricio A., Heinen, Christian, Wortelboer, Heleen M., Verwei, Miriam, Langguth, Peter

“…[Display omitted] Chitosan is object of pharmaceutical research as a candidate permeability enhancer. However, chitosan was recently shown to reduce the oral…”
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Recent increase in campylobacteriosis incidence in the Netherlands associated with proton-pump inhibitor use by Bouwknegt, Martijn, PhD, van Pelt, Wilfrid, PhD, Kubbinga, Marlies, MSc, Weda, Marjolein, PhD, Havelaar, Arie H, Prof

“…Abstract Background Proton pump inhibitors (PPIs) are prescribed to patients requiring prevention or treatment of gastric and duodenal ulcers. PPIs inhibit…”
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A phytochemical study of lignans in whole plants and cell suspension cultures of Anthriscus sylvestris by Koulman, Albert, Kubbinga, Marlies E, Batterman, Sieb, Woerdenbag, Herman J, Pras, Niesko, Woolley, Jack G, Quax, Wim J

“…In the roots of Anthriscus sylvestris 12 different lignans were detected. Arctigenin, dimethylmatairesinol, dimethylthujaplicatin, podophyllotoxin,…”
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Novel insights into excipient effects on the biopharmaceutics of APIs from different BCS classes: Lactose in solid oral dosage forms by Kubbinga, Marlies, Moghani, Laura, Langguth, Peter

“…[Display omitted] Excipients encompass a wide range of properties that are of importance for the resulting drug product. Regulatory guidelines on biowaivers…”
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In vivo methods for drug absorption – Comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects by Sjögren, Erik, Abrahamsson, Bertil, Augustijns, Patrick, Becker, Dieter, Bolger, Michael B., Brewster, Marcus, Brouwers, Joachim, Flanagan, Talia, Harwood, Matthew, Heinen, Christian, Holm, René, Juretschke, Hans-Paul, Kubbinga, Marlies, Lindahl, Anders, Lukacova, Viera, Münster, Uwe, Neuhoff, Sibylle, Nguyen, Mai Anh, Peer, Achiel van, Reppas, Christos, Hodjegan, Amin Rostami, Tannergren, Christer, Weitschies, Werner, Wilson, Clive, Zane, Patricia, Lennernäs, Hans, Langguth, Peter

“…[Display omitted] This review summarizes the current knowledge on anatomy and physiology of the human gastrointestinal tract in comparison with that of common…”
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The impact of the EMA change in definition of "dose" on the BCS dose-solubility ratio: a review of the biowaiver monographs by Sediq, Ahmad, Kubbinga, Marlies, Langguth, Peter, Dressman, Jennifer

“…The Biopharmaceutics Classification System (BCS) defines the solubility characteristics of an active pharmaceutical substance based on its dose-solubility…”
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Risk analysis in bioequivalence and biowaiver decisions by Kubbinga, Marlies, Langguth, Peter, Barends, Dirk

“…ABSTRACT This article evaluates the current biowaiver guidance documents published by the FDA, EU and WHO from a risk based perspective. The authors introduce…”
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Risk analysis in bioequivalence and biowaiver decisions : Relationships Between In Vitro Dissolution and In Vivo Response: Part II by KUBBINGA, Marlies, LANGGUTH, Peter, BARENDS, Dirk

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