Search Results - "Kuba, Robert"
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Prenatal Exposure to Valproic Acid Affects Microglia and Synaptic Ultrastructure in a Brain-Region-Specific Manner in Young-Adult Male Rats: Relevance to Autism Spectrum Disorders
Published in International journal of molecular sciences (18-05-2020)“…Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental conditions categorized as synaptopathies. Environmental risk factors contribute…”
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Glutamate, Glutamine and GABA Levels in Rat Brain Measured Using MRS, HPLC and NMR Methods in Study of Two Models of Autism
Published in Frontiers in molecular neuroscience (16-11-2018)“…The disorders of the glutamatergic neurotransmission have been associated with pathogenesis of autism. In this study we evaluated the impact of the and test…”
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Cortical Synaptic Transmission and Plasticity in Acute Liver Failure Are Decreased by Presynaptic Events
Published in Molecular neurobiology (01-02-2018)“…Neurological symptoms of acute liver failure (ALF) reflect decreased excitatory transmission, but the status of ALF-affected excitatory synapse has not been…”
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Intracerebrally recorded high frequency oscillations: Simple visual assessment versus automated detection
Published in Clinical neurophysiology (01-10-2013)“…Highlights • Simple visual assessment of SEEG traces (filtered in frequency ranges 80–200 Hz and 200–450 Hz) and standard automated detection of HFO contribute…”
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Interictal and Ictal EEG Activity in the Basal Ganglia: An SEEG Study in Patients with Temporal Lobe Epilepsy
Published in Epilepsia (Copenhagen) (01-03-2002)“…Purpose: The interictal and ictal EEG activity in the basal ganglia in patients with temporal lobe epilepsy were studied during invasive EEG monitoring…”
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Atypical hemispheric language dominance in left temporal lobe epilepsy as a result of the reorganization of language functions
Published in Epilepsy & behavior (01-08-2003)“…Hemispheric language dominance, as determined by intracarotid short-acting barbiturate injections (Wada testing), was retrospectively evaluated in 44…”
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Cognitive potentials in the basal ganglia-frontocortical circuits. An intracerebral recording study
Published in Experimental brain research (01-10-2004)“…We studied cognitive functions related to processing sensory and motor activities in the basal ganglia (BG), specifically in the putamen and in cortical…”
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Effect of Vagal Nerve Stimulation on Interictal Epileptiform Discharges: A Scalp EEG Study
Published in Epilepsia (Copenhagen) (01-10-2002)“…Purpose: To investigate the effects of acute vagal nerve stimulation (VNS) on interictal epileptiform discharges (IEDs). Methods: Fifteen epilepsy patients,…”
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Complete Loss of the Cytoplasmic Carboxyl Terminus of the KCNQ2 Potassium Channel: A Novel Mutation in a Large Czech Pedigree with Benign Neonatal Convulsions or Other Epileptic Phenotypes
Published in Epilepsia (Copenhagen) (01-04-2004)“…Purpose: Benign neonatal familial convulsions (BNFCs) represent a rare epileptic disorder with autosomal dominant mode of inheritance. To date, two…”
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17. Sexual functions and dysfunctions in patients with epilepsy
Published in Epilepsy & behavior (01-04-2010)Get full text
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Do the basal ganglia inhibit seizure activity in temporal lobe epilepsy?
Published in Epilepsy & behavior (01-09-2012)“…Abstract There is substantial evidence in the literature that the basal ganglia (BG), namely the striatum and pallidum, are involved in temporal lobe epilepsy…”
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Unruptured intracranial aneurysm as a cause of focal epilepsy: an excellent postoperative outcome after intra-arterial treatment
Published in Epileptic disorders (01-03-2004)“…This report involves a patient suffering from focal epilepsy caused by an unruptured, intracranial aneurysm (UIA), and her treatment using intravascular…”
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A brain atlas of axonal and synaptic delays based on modelling of cortico-cortical evoked potentials
Published in Brain (London, England : 1878) (03-06-2022)“…Epilepsy presurgical investigation may include focal intracortical single-pulse electrical stimulations with depth electrodes, which induce cortico-cortical…”
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Dose-dependent teratogenicity of valproate in mono- and polytherapy: an observational study
Published in Neurology (08-09-2015)“…To assess the risk of major congenital malformations (MCMs) in association with maternal use of valproic acid (VPA) in monotherapy or adjunctive therapy, and…”
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16. fMRI and eeg studies of the role of basal ganglia in epilepsy
Published in Clinical neurophysiology (01-03-2015)“…(1) In the fMRI study the impact of epilepsy on the functional brain connectivity (FC) of the BG in two large-scale networks, the default mode network (DMN)…”
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Activation-induced chromatin reorganization in neurons depends on HDAC1 activity
Published in Cell reports (Cambridge) (15-02-2022)“…Spatial chromatin organization is crucial for transcriptional regulation and might be particularly important in neurons since they dramatically change their…”
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Long-term seizure outcome in patients with juvenile absence epilepsy; a retrospective study in a tertiary referral center
Published in Seizure (London, England) (01-06-2014)“…Abstract Purpose The study aim was to evaluate pharmacotherapy effects and long-term seizure outcomes in patients with juvenile absence epilepsy (JAE) during a…”
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Intracranial EEG seizure onset patterns in unilateral temporal lobe epilepsy and their relationship to other variables
Published in Clinical neurophysiology (01-06-2013)“…Highlights ► Very early seizure onset frequencies in invasive EEG in patient with temporal lobe epilepsy could be predictive factor for their outcome. ► Higher…”
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A brain atlas of axonal and synaptic delays based on modelling of cortico-cortical evoked potentials
Published in Brain (London, England : 1878) (01-05-2022)“…Abstract Epilepsy presurgical investigation may include focal intracortical single-pulse electrical stimulations with depth electrodes, which induce…”
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Postictal psychosis and its electrophysiological correlates in invasive EEG: A case report study and literature review
Published in Epilepsy & behavior (01-04-2012)“…Abstract We identified two patients with medically refractory temporal lobe epilepsy, from whom intracranial EEG recordings were obtained at the time of…”
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