Search Results - "Kuang, Binhai"

Novel aminopeptidase N inhibitors derived from 1,3,4-thiadiazole scaffold by Tu, GuoGang, Li, ShaoHua, Huang, HuiMing, Li, Gang, Xiong, Fang, Mai, Xi, Zhu, HuaWei, Kuang, BinHai, Xu, Wen Fang

“…The synthesis and biological activity of a new series of 1,3,4-thiadiazole scaffold is described. The aminopeptidase N (APN/CD13), overexpressed in tumor…”
Get full text

3D-QSAR studies on flavone-8-acetic acid derivatives of aminopeptidase N inhibitors by Tang, XianShuai, Qu, QingLian, Kuang, BinHai, Li, ShaoHua, Tu, GuoGang

“…The 3D-QSARs models of 29 flavone-8-acetic acid derivatives of aminopeptidase N inhibitors were generated by applying the molecular interaction fields at…”
Get more information

3D-QSAR Studies, Molecular Dynamics Simulation and Free Energy Calculation of APN Inhibitors by Qu, Qinglian, Tang, Xianshuai, Kuang, Binhai, Li, Shaohua, Tu, Guogang

Get full text

Exploring ligand dissociation pathways from aminopeptidase N using random acceleration molecular dynamics simulation by Liu, Ya, Tu, GuoGang, Lai, XiaoPing, Kuang, BinHai, Li, ShaoHua

“…Aminopeptidase N (APN) is a zinc-dependent ectopeptidase involved in cell proliferation, secretion, invasion, and angiogenesis, and is widely recognized as an…”
Get full text

Design, synthesis and biological evaluation of CB1 cannabinoid receptor ligands derived from the 1,5-diarylpyrazole scaffold by Tu, GuoGang, Xiong, Fang, Huang, HuiMing, Kuang, BinHai, Li, ShaoHua

“…The CB1 receptor belongs to the G-protein-coupled receptor superfamily. CB1 antagonism has been considered as a new therapeutic target for the treatment of…”
Get more information