Search Results - "Kuan, Emma L"

A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation by Duivenvoorden, Raphaël, Tang, Jun, Cormode, David P., Mieszawska, Aneta J., Izquierdo-Garcia, David, Ozcan, Canturk, Otten, Maarten J., Zaidi, Neeha, Lobatto, Mark E., van Rijs, Sarian M., Priem, Bram, Kuan, Emma L., Martel, Catherine, Hewing, Bernd, Sager, Hendrik, Nahrendorf, Matthias, Randolph, Gwendalyn J., Stroes, Erik S. G., Fuster, Valentin, Fisher, Edward A., Fayad, Zahi A., Mulder, Willem J. M.

“…Inflammation is a key feature of atherosclerosis and a target for therapy. Statins have potent anti-inflammatory properties but these cannot be fully exploited…”
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Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes by Jakubzick, Claudia, Bogunovic, Milena, Bonito, Anthony J, Kuan, Emma L, Merad, Miriam, Randolph, Gwendalyn J

“…Observations that dendritic cells (DCs) constitutively enter afferent lymphatic vessels in many organs and that DCs in some tissues, such as the lung, turnover…”
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Normal dendritic cell mobilization to lymph nodes under conditions of severe lymphatic hypoplasia by Platt, Andrew M, Rutkowski, Joseph M, Martel, Catherine, Kuan, Emma L, Ivanov, Stoyan, Swartz, Melody A, Randolph, Gwendalyn J

“…To address the requirement for lymphatic capillaries in dendritic cell (DC) mobilization from skin to lymph nodes (LNs), we used mice bearing one inactivated…”
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A tumor–myeloid cell axis, mediated via the cytokines IL-1α and TSLP, promotes the progression of breast cancer by Kuan, Emma L., Ziegler, Steven F.

“…Tumors actively manipulate the immune response through the production of factors that attract immune cells and subsequently alter their ability to recognize…”
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Collecting lymphatic vessel permeability facilitates adipose tissue inflammation and distribution of antigen to lymph node-homing adipose tissue dendritic cells by Kuan, Emma L, Ivanov, Stoyan, Bridenbaugh, Eric A, Victora, Gabriel, Wang, Wei, Childs, Ed W, Platt, Andrew M, Jakubzick, Claudia V, Mason, Robert J, Gashev, Anatoliy A, Nussenzweig, Michel, Swartz, Melody A, Dustin, Michael L, Zawieja, David C, Randolph, Gwendalyn J

“…Collecting lymphatic vessels (CLVs), surrounded by fat and endowed with contractile muscle and valves, transport lymph from tissues after it is absorbed into…”
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Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage by Thomas, Susan N, Rutkowski, Joseph M, Pasquier, Miriella, Kuan, Emma L, Alitalo, Kari, Randolph, Gwendalyn J, Swartz, Melody A

“…Lymphatic vessels transport interstitial fluid, soluble Ag, and immune cells from peripheral tissues to lymph nodes (LNs), yet the contribution of peripheral…”
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Publisher Correction: A tumor–myeloid cell axis, mediated via the cytokines IL-1α and TSLP, promotes the progression of breast cancer by Kuan, Emma L., Ziegler, Steven F.

“…In the version of this article initially published, the far right label along the horizontal axis of the right plot of Fig. 1e (4T1- Tslp –/– 4-6), the middle…”
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CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability by Ivanov, Stoyan, Scallan, Joshua P, Kim, Ki-Wook, Werth, Kathrin, Johnson, Michael W, Saunders, Brian T, Wang, Peter L, Kuan, Emma L, Straub, Adam C, Ouhachi, Melissa, Weinstein, Erica G, Williams, Jesse W, Briseño, Carlos, Colonna, Marco, Isakson, Brant E, Gautier, Emmanuel L, Förster, Reinhold, Davis, Michael J, Zinselmeyer, Bernd H, Randolph, Gwendalyn J

“…Lymphatic collecting vessels direct lymph into and from lymph nodes (LNs) and can become hyperpermeable as the result of a previous infection. Enhanced…”
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Erratum: A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation by Duivenvoorden, Raphaël, Tang, Jun, Cormode, David P., Mieszawska, Aneta J., Izquierdo-Garcia, David, Ozcan, Canturk, Otten, Maarten J., Zaidi, Neeha, Lobatto, Mark E., van Rijs, Sarian M., Priem, Bram, Kuan, Emma L., Martel, Catherine, Hewing, Bernd, Sager, Hendrik, Nahrendorf, Matthias, Randolph, Gwendalyn J., Stroes, Erik S. G., Fuster, Valentin, Fisher, Edward A., Fayad, Zahi A., Mulder, Willem J. M.

“…Nature Communications 5: Article number: 3065 (2014); Published: 20 January 2014; Updated: 19 March 2014. The affiliation details for Edward A. Fisher are…”
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Publisher Correction: A tumor-myeloid cell axis, mediated via the cytokines IL-1[alpha] and TSLP, promotes the progression of breast cancer by Kuan, Emma L, Ziegler, Steven F

“…In the version of this article initially published, the far right label along the horizontal axis of the right plot of Fig. 1e (4T1-Tslp.sup.-/- 4-6), the…”
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A tumor-myeloid cell axis, mediated via the cytokines IL-1[alpha] and TSLP, promotes the progression of breast cancer by Kuan, Emma L, Ziegler, Steven F

“…Tumors actively manipulate the immune response through the production of factors that attract immune cells and subsequently alter their ability to recognize…”
Get full text

A tumor-myeloid cell axis, mediated via interleukin 1α and TSLP, promotes breast cancer progression by Kuan, Emma L., Ziegler, Steven F.

“…Tumors actively manipulate the immune response through the production of factors that attract immune cells and subsequently alter their ability to recognize…”
Get full text

Abstract 5331: Spatial resolution of immune cell lineages in the tumor microenvironment of plasma cell dyscrasias by Dillon, Medbh A., Arvidson, Lisa, Phalen, Cole G., Ishibashi, Julian R., Johanneson, John B., Thomson, Zachary J., Zhao, Peiyao A., Malone, Jocelin, Kopp, Mackenzie S., Norton, Matthew, Spang, Gabriella, Ludmann, Susan A., Savage, Adam K., Gustafson, Claire E., Glass, Marla, Kuan, Emma L., Peng, Tao, Graybuck, Lucas T., Li, Xiao-jun, Torgerson, Troy R., Skene, Peter J., Goldrath, Ananda W., Jensen, Samuel, Anover-Sombke, Stephanie, Angus-Hill, Melinda L.

“…Plasma cell dyscrasias (PCDs) are diseases of the hematologic system, with Multiple Myeloma as the most common disease. Less common PCDs include primary and…”
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Collecting lymphatic vessel permeability facilitates adipose tissue inflammation and distribution of antigen to lymph node-homing adipose tissue DCs by Kuan, Emma L., Ivanov, Stoyan, Bridenbaugh, Eric A., Victora, Gabriel, Wang, Wei, Childs, Ed W., Platt, Andrew M., Jakubzick, Claudia V., Mason, Robert J., Gashev, Anatoliy A., Nussenzweig, Michel, Swartz, Melody A., Dustin, Michael L., Zawieja, David C., Randolph, Gwendalyn J.

“…Collecting lymphatic vessels (CLVs), surrounded by fat and endowed with contractile muscle and valves, transport lymph from tissues after it is absorbed into…”
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CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability by Ivanov, Stoyan, Scallan, Joshua P, Kim, Ki-Wook, Werth, Kathrin, Johnson, Michael W, Saunders, Brian T, Wang, Peter L, Kuan, Emma L, Straub, Adam C, Ouhachi, Melissa, Weinstein, Erica G, Williams, Jesse W, Briseno, Carlos, Colonna, Marco, Isakson, Brant E, Gautier, Emmanuel L, Forster, Reinhold, Davis, Michael J, Zinselmeyer, Bernd H, Randolph, Gwendalyn J

“…Lymphatic collecting vessels direct lymph into and from lymph nodes (LNs) and can become hyperpermeable as the result of a previous infection. Enhanced…”
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Abstract 9601: A Statin-Loaded Nanotherapy Increases Anti-Inflammatory Effects of Statin on Atherosclerosis by Tang, Jun, Duivenvoorden, Raphael, Izquierdo-Garcia, David, Cormode, David P, Stroes, Erik S, Lobatto, Mark E, Kuan, Emma L, Randolph, Gwendalyn L, Fuster, Valentin, Fisher, Edward A, Mulder, Willem J

“…Abstract only Introduction: Statins have a potent cholesterol lowering capability and have shown anti-inflammatory effects, but these effects are limited. We…”
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Abstract 19487: Simvastatin Loaded High-Density Lipoprotein Nanoparticles Reduce Inflammation in Atherosclerotic Plaques by Directly Acting on Plaque Macrophages and Inflammatory Monocytes by Tang, Jun, Duivenvoorden, Raphael, Hewing, Bernd, Izquierdo-Garcia, David, Mieszawska, Aneta J, van Rijs, Sarian M, Cormode, David P, Ozcan, Canturk, Kuan, Emma L, Martel, Catherine, Lobatto, Mark E, Stroes, Erik S, Randolph, Gwendalyn J, Fuster, Valentin, Fisher, Edward A, Fayad, Zahi A, Mulder, Willem J

“…Abstract only Rationale: Although statins have been shown to have anti-inflammatory pleiotropic effects in experimental studies, the poor plaque targeting of…”
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Knockdown of CCR7 or Its Ligands Causes a Loss of Central Nervous System Involvement in Notch1 Induced T-ALL by Buonamici, Silvia, Trimarchi, Thomas, Klinakis, Apostolos, Reavie, Linsey, Mar, Brenton G., Gehrie, Eric, Kuan, Emma L., Randolph, Gwendalyn J., Bromberg, Jonathan, Aifantis, Iannis

“…Intensive chemotherapy helps achieve remission in the vast majority of acute lymphoblastic leukemia (ALL) patients. A subset of these cases, T-cell ALL…”
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