Search Results - "Kübler, Wolfgang"

The Theranostic PSMA Ligand PSMA-617 in the Diagnosis of Prostate Cancer by PET/CT: Biodistribution in Humans, Radiation Dosimetry, and First Evaluation of Tumor Lesions by Afshar-Oromieh, Ali, Hetzheim, Henrik, Kratochwil, Clemens, Benesova, Martina, Eder, Matthias, Neels, Oliver C, Eisenhut, Michael, Kübler, Wolfgang, Holland-Letz, Tim, Giesel, Frederik L, Mier, Walter, Kopka, Klaus, Haberkorn, Uwe

“…PET imaging with the prostate-specific membrane antigen (PSMA)-targeted radioligand (68)Ga-PSMA-11 is regarded as a significant step forward in the diagnosis…”
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Radiation dosimetry of 68Ga-PSMA-11 (HBED-CC) and preliminary evaluation of optimal imaging timing by Afshar-Oromieh, Ali, Hetzheim, Henrik, Kübler, Wolfgang, Kratochwil, Clemens, Giesel, Frederik L., Hope, Thomas A., Eder, Matthias, Eisenhut, Michael, Kopka, Klaus, Haberkorn, Uwe

“…Purpose The clinical introduction of 68 Ga-PSMA-11 (“HBED-CC”) ligand targeting the prostate-specific membrane antigen (PSMA) has been regarded as a…”
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Pulmonary hypertension associated with left heart disease: Updated Recommendations of the Cologne Consensus Conference 2018 by Rosenkranz, Stephan, Lang, Irene M., Blindt, Rüdiger, Bonderman, Diana, Bruch, Leonhard, Diller, Gerhard P., Felgendreher, Ralf, Gerges, Christian, Hohenforst-Schmidt, Wolfgang, Holt, Stephan, Jung, Christian, Kindermann, Ingrid, Kramer, Tilmann, Kübler, Wolfgang M., Mitrovic, Veselin, Riedel, Andreas, Rieth, Andreas, Schmeisser, Alexander, Wachter, Rolf, Weil, Joachim, Opitz, Christian F.

“…In the summer of 2016, delegates from the German Society of Cardiology (DGK), the German Respiratory Society (DGP), and the German Society of Pediatric…”
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Angiotensin Induces Inflammatory Activation of Human Vascular Smooth Muscle Cells by Kranzhöfer, Roger, Schmidt, Joachim, Pfeiffer, Carolein A.H, Hagl, Siegfried, Libby, Peter, Kübler, Wolfgang

“…Multiple data suggest that the renin-angiotensin system contributes to the pathogenesis of atherosclerosis. The atherogenic effect of the renin-angiotensin…”
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Re: Sun-Kui Ke et al. TRiPping over vasotonus regulation in the lung by Gollasch, Maik, Kübler, Wolfgang M

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Abnormal pulmonary artery pressure response in asymptomatic carriers of primary pulmonary hypertension gene by GRÜNIG, E, JANSSEN, B, MERELES, D, BARTH, U, BORST, M. M, VOGT, I. R, FISCHER, C, OLSCHEWSKI, H, KUECHERER, H. F, KÜBLER, W

“…Familial primary pulmonary hypertension (PPH) is an autosomal-dominant inherited disease with incomplete penetrance and poor prognosis. This study was…”
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Endothelial dysfunction of coronary resistance arteries is improved by tetrahydrobiopterin in atherosclerosis by TIEFENBACHER, Christiane P, BLEEKE, Tina, VAHL, Christian, AMANN, Kerstin, VOGT, Achim, KÜBLER, Wolfgang

“…Tetrahydrobiopterin (BH4), an essential cofactor for the synthesis of NO, improves endothelial dysfunction after ischemia/reperfusion. Therefore, we…”
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Monocyte Chemoattractant Protein-1 Induces Proliferation and Interleukin-6 Production in Human Smooth Muscle Cells by Differential Activation of Nuclear Factor-κB and Activator Protein-1 by Viedt, Christiane, Vogel, Judith, Athanasiou, Thomas, Shen, Weili, Orth, Stephan R, Kübler, Wolfgang, Kreuzer, Jörg

“…Inflammatory response and chemotaxis of vascular wall cells play an important pathogenic role in the development of atherosclerosis. Monocyte chemoattractant…”
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Low-dose radioactive endovascular stents prevent smooth muscle cell proliferation and neointimal hyperplasia in rabbits by HEHRLEIN, C, GOLLAN, C, DÖNGES, K, METZ, J, RIESSEN, R, FEHSENFELD, P, VON HODENBERG, E, KÜBLER, W

“…Restenosis induced by smooth muscle cell (SMC) migration and proliferation and neointimal thickening limits the clinical success of balloon angioplasty and…”
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Heparin inhibits ligand binding to the leukocyte integrin Mac-1 (CD11b/CD18) by PETER, K, SCHWARZ, M, CONRADT, C, NORDT, T, MOSER, M, KÜBLER, W, BODE, C

“…The clinical benefits of heparin reach beyond its anticoagulative properties. Recently, it has been described that leukocytes adhere on immobilized heparin…”
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Transfer of the Human NaI Symporter Gene Enhances Iodide Uptake in Hepatoma Cells by Haberkorn, Uwe, Henze, Markus, Altmann, Annette, Jiang, Shiming, Morr, Iris, Mahmut, Miriam, Peschke, Peter, Kubler, Wolfgang, Debus, Jurgen, Eisenhut, Michael

“…The characteristic feature of thyroid cells of taking up iodide enables benign thyroid diseases and differentiated thyroid carcinoma to be successfully treated…”
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Deletion of Protein Kinase A Phosphorylation Sites in the HERG Potassium Channel Inhibits Activation Shift by Protein Kinase A by Thomas, Dierk, Zhang, Wei, Karle, Christoph A., Kathöfer, Sven, Schöls, Wolfgang, Kübler, Wolfgang, Kiehn, Johann

“…We investigated the role of protein kinase A (PKA) in regulation of the human ether-a-go-go-related gene (HERG) potassium channel activation. HERG clones with…”
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Cardio-pulmonary interaction in HFpEF by Grune, Jana, Hegemann, Niklas, Kübler, Wolfgang M.

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Two Distinct Mechanisms Mediate a Differential Regulation of Protein Kinase C Isozymes in Acute and Prolonged Myocardial Ischemia by Strasser, Ruth H, Simonis, Gregor, Schön, Steffen P, Braun, Martin U, Ihl-Vahl, Renate, Weinbrenner, Christof, Marquetant, Rainer, Kübler, Wolfgang

“…An activation of protein kinase C (PKC) in acute myocardial ischemia has been shown previously using its translocation to the plasma membrane as an indirect…”
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The Neuronal Norepinephrine Transporter in Experimental Heart Failure: Evidence for a Posttranscriptional Downregulation by Backs, Johannes, Haunstetter, Armin, Gerber, Stefan H., Metz, Jürgen, Borst, Mathias M., Strasser, Ruth H., Kübler, Wolfgang, Haass, Markus

“…An impairment of norÍepinephrine (NE) re-uptake by the neuronal NE transporter (NET) has been shown to contribute to the increased cardiac net-release of NE in…”
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Mediastinal emphysema after long‐distance flight with ketoacidosis and underlying diabetes mellitus type 1 by Ardila Pardo, Gracia Lana, Kübler, Wolfgang Michael, Witzenrath, Martin, Oestmann, Jörg‐Wilhelm

“…A 21‐year old female with diabetes mellitus type 1 presented to our hospital's emergency department having suffered from shortness of breath, mild chest pain,…”
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Primary pulmonary hypertension in children may have a different genetic background than in adults by GRÜNIG, Ekkehard, KOEHLER, Rolf, VON HIPPEL, Albrecht, ULMER, Herbert E, KÜBLER, Wolfgang, KATUS, Hugo A, BARTRAM, Claus R, SCHRANZ, Dietmar, JANSSEN, Bart, MILTENBERGER-MILTENYI, Gabriel, ZIMMERMANN, Rainer, GORENFLO, Matthias, MERELES, Derliz, ARNOLD, Karlin, NAUST, Barbara, WILKENS, Heinrike, BENZ, Andreas

“…Mutations of the bone morphogenetic protein receptor II (BMPR2) gene on chromosome 2q33 can cause familial primary pulmonary hypertension (PPH) and may occur…”
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HERG Potassium Channel Activation Is Shifted by Phorbol Esters via Protein Kinase A-dependent Pathways by Kiehn, Johann, Karle, Christoph, Thomas, Dierk, Yao, Xiaozhou, Brachmann, Johannes, Kübler, Wolfgang

“…We investigated the effects of the phorbol ester phorbol 12-myristate 13-acetate (PMA) on the rapid component of the delayed rectifier potassium current, IKr,…”
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Plasminogen activator inhibitor type-1 (PAI-1) and its role in cardiovascular disease by Nordt, T K, Peter, K, Ruef, J, Kübler, W, Bode, C

“…Cardiovascular disease is responsible for approximately 50% of total mortality in Europe, the USA and Japan. Established risk factors including smoking,…”
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Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels by Kiehn, J, Thomas, D, Karle, C A, Schöls, W, Kübler, W

“…The human ether-a-go-go-related gene (HERG) encodes a K+ channel with biophysical properties nearly identical to the rapid component of the cardiac-delayed…”
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