Candida auris : Disinfectants and Implications for Infection Control

is a rapidly emerging pathogen and is able to cause severe infections with high mortality rates. It is frequently misidentified in most clinical laboratories, thus requiring more specialized identification techniques. Furthermore, several clinical isolates have been found to be multidrug resistant a...

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Published in:Frontiers in microbiology Vol. 9; p. 726
Main Authors: Ku, Tsun S N, Walraven, Carla J, Lee, Samuel A
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 12-04-2018
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Summary:is a rapidly emerging pathogen and is able to cause severe infections with high mortality rates. It is frequently misidentified in most clinical laboratories, thus requiring more specialized identification techniques. Furthermore, several clinical isolates have been found to be multidrug resistant and there is evidence of nosocomial transmission in outbreak fashion. Appropriate infection control measures will play a major role in controlling the management and spread of this pathogen. Unfortunately, there are very few data available on the effectiveness of disinfectants against . Chlorine-based products appear to be the most effective for environmental surface disinfection. Other disinfectants, although less effective than chlorine-based products, may have a role as adjunctive disinfectants. A cleaning protocol will also need to be established as the use of disinfectants alone may not be sufficient for maximal decontamination of patient care areas. Furthermore, there are fewer data on the effectiveness of antiseptics against for patient decolonization and hand hygiene for healthcare personnel. Chlorhexidine gluconate has shown some efficacy in studies but there are reports of patients with persistent colonization despite twice daily body washes with this disinfectant. Hand hygiene using soap and water, with or without chlorhexidine gluconate, may require the subsequent use of alcohol-based hand sanitizer for maximal disinfection. Further studies will be needed to validate the currently studied disinfectants for use in real-world settings.
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Edited by: Gordon Ramage, University of Glasgow, United Kingdom
Reviewed by: Marilene Henning Vainstein, Federal University of Rio Grande do Sul (UFRGS), Brazil; Priya Uppuluri, University of California, Los Angeles, United States
This article was submitted to Antimicrobials, Resistance and Chemotherapy, a section of the journal Frontiers in Microbiology
ISSN:1664-302X
1664-302X
DOI:10.3389/fmicb.2018.00726