Search Results - "Ku, Dennis T. L"
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Case report: Treatment response of NF-1-associated bladder ganglioneuroma to trametinib
Published in Frontiers in oncology (12-07-2024)“…We present the clinical course of a 4-year-old girl with neurofibromatosis type 1-associated, unresectable, symptomatic urinary bladder ganglioneuroma. She was…”
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Genome-Wide DNA Methylation Profiling as Frontline Diagnostics for Central Nervous System Embryonal Tumors in Hong Kong
Published in Cancers (01-10-2023)“…This paper examines the link between CNS tumor biology and heterogeneity and the use of genome-wide DNA methylation profiling as a clinical diagnostic…”
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Incidence and Outcomes of CNS Tumors in Chinese Children: Comparative Analysis With the Surveillance, Epidemiology, and End Results Program
Published in JCO global oncology (01-05-2020)“…Despite being the most common pediatric solid tumors, incidence and outcome of CNS tumors in Chinese children have not been systematically reported. We…”
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Durable disease control with apatinib, irinotecan and temozolomide in a case of metastatic primitive myxoid mesenchymal tumour of infancy
Published in Pediatric blood & cancer (01-03-2023)Get full text
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High detection rate of circulating-tumor DNA from cerebrospinal fluid of children with central nervous system germ cell tumors
Published in Acta neuropathologica communications (20-11-2024)“…Central nervous system germ cell tumors (CNS-GCT) are malignant neoplasms that arise predominantly during adolescence and young adulthood. These tumors are…”
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Case Report: Primary Thoracic Low-Grade Fibromyxoid Sarcoma in a Young Girl Presenting With Mediastinal Mass Syndrome
Published in Frontiers in pediatrics (17-06-2022)“…Low-grade fibromyxoid sarcomas (LGFMSs) are typically adult-onset tumors that arise from the extremities. Here, we report an exceptional case of primary…”
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IMG-19. CLINICAL UTILITY OF NON-FDG PET-MRI IN CHILDREN WITH CNS NEOPLASMS: A TERRITORY-WIDE STUDY FROM HONG KONG
Published in Neuro-oncology (Charlottesville, Va.) (18-06-2024)Get full text
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LGG-17. CLINICAL OUTCOME OF PEDIATRIC LOW GRADE GLIOMA WITH POSITIVE BRAF-FUSION TREATED WITH MEK INHIBITOR
Published in Neuro-oncology (Charlottesville, Va.) (01-06-2021)Get full text
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GERM-03. CLINICAL FEATURES AND OUTCOME OF CHILDREN WITH INTRACRANIAL NON-GERMINOMATOUS GERM CELL TUMORS: A POPULATION-BASED STUDY IN HONG KONG
Published in Neuro-oncology (Charlottesville, Va.) (01-06-2021)“…The incidence of central nervous system non-germinomatous germ cell tumor (NGGCT) is four times higher in Chinese children than in the Western population…”
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HGG-37. A case ofETV6-NTRK3 fusion driven infantile hemispheric glioma (IHG) with acquired drug resistance against first- and second-generation NTRK-inhibitors
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…A 3-month-old girl had left cerebral infantile hemispheric glioma (IHG), H3 wild type (wt), Grade IV (WHO2020) with diffuse leptomeningeal and spinal…”
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HGG-37. A case of ETV6-NTRK3 fusion driven infantile hemispheric glioma (IHG) with acquired drug resistance against first- and second-generation NTRK-inhibitors
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…A 3-month-old girl had left cerebral infantile hemispheric glioma (IHG), H3 wild type (wt), Grade IV (WHO2020) with diffuse leptomeningeal and spinal…”
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PATH-10. Nanopore sequencing reveals novel ALK fusion with interposed element in a neonate with hemispheric glioma
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…Here we describe the clinical course and unique molecular findings in a female neonate with infantile hemispheric glioma (IHG). The patient presented at the…”
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LINC-20. INFANT BRAIN TUMOURS IN HONG KONG
Published in Neuro-oncology (Charlottesville, Va.) (04-12-2020)Get full text
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OMIC-07. FEASIBILITY AND UTILITY OF EPIGENOMIC PROFILING FOR CHILDHOOD CNS TUMORS IN HONG KONG
Published in Neuro-oncology (Charlottesville, Va.) (01-06-2021)“…Genome-wide DNA methylation profiling has emerged as an important diagnostic tool that complements histopathology for CNS tumors in children and adults…”
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LGG-39. EPIDEMIOLOGY, MANAGEMENT AND OUTCOME OF PAEDIATRIC LOW GRADE GLIOMA IN HONG KONG
Published in Neuro-oncology (Charlottesville, Va.) (22-06-2018)“…Abstract METHOD Retrospective cohort for patients age 0 to 18 years old from January 1999 to Aug 2016 diagnosed to have low grade glioma. RESULT Fifty-five…”
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GERM-16. A MULTI-CENTRE CLINICAL TRIAL OF CNS GERM CELL TUMOURS IN HONG KONG
Published in Neuro-oncology (Charlottesville, Va.) (22-06-2018)“…Abstract METHOD This clinical trial started from January 2008 and ended in June 2014. Patients who were suspected to have germinoma received a biopsy, followed…”
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