Search Results - "Kshatri, Aravind Singh"
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Discovery of a novel and highly selective JAK3 inhibitor as a potent hair growth promoter
Published in Journal of translational medicine (18-04-2024)“…JAK-STAT signalling pathway inhibitors have emerged as promising therapeutic agents for the treatment of hair loss. Among different JAK isoforms, JAK3 has…”
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Molecular mechanisms underlying the effect of the novel BK channel opener GoSlo: Involvement of the S4/S5 linker and the S6 segment
Published in Proceedings of the National Academy of Sciences - PNAS (17-02-2015)“…Significance Large-conductance Ca ²⁺-activated K ⁺ (BK) calcium-activated potassium channels alter the excitability of a wide variety of cells including nerves…”
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Identification of a novel GSK3β inhibitor involved in abrogating KRas dependent pancreatic tumors in Wnt/beta-catenin and NF-kB dependent manner
Published in Life sciences (1973) (15-08-2024)“…Pancreatic cancer is an aggressive malignancy with a poor survival rate because it is difficult to diagnose the disease during its early stages. The currently…”
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